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short-chain dehydrogenases/reductases (237) 237
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Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 07/2017, Volume 171, pp. 157 - 177
Several members of the short-chain dehydrogenase/reductase (SDR) enzyme family play fundamental roles in adrenal and gonadal steroidogenesis as well as in the... 
Virtual screening | Hydroxysteroid dehydrogenase | Drug development | Short-chain dehydrogenase/reductase | Endocrine disrupting chemicals | CARBONYL REDUCTASE SNIFFER | SELECTIVE NONSTEROIDAL INHIBITORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYSTAL-STRUCTURES | BETA-HYDROXYSTEROID DEHYDROGENASE | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-1 17-BETA-HSD1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE | ENDOCRINOLOGY & METABOLISM | BICYCLIC SUBSTITUTED HYDROXYPHENYLMETHANONES | 11-BETA-HSD1 INHIBITORS | (-)-GOSSYPOLS POTENTLY INHIBIT | STRUCTURE-BASED DESIGN | Chemistry, Pharmaceutical - methods | Hydroxysteroid Dehydrogenases - chemistry | Expert Systems | Humans | Substrate Specificity | Isoenzymes - chemistry | Machine Learning | Endocrine Disruptors - pharmacology | Isoenzymes - metabolism | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Drug Design | Hydroxysteroid Dehydrogenases - metabolism | Toxicology - methods | Computer-Aided Design - trends | Binding Sites | Chemistry, Pharmaceutical - trends | Endocrine Disruptors - metabolism | Enzyme Inhibitors - metabolism | Endocrine Disruptors - chemistry | Computational Biology | Enzyme Inhibitors - pharmacology | Toxicology - trends | Molecular Docking Simulation - trends | High-Throughput Screening Assays - trends | Endocrine Disruptors - toxicity | Animals | Validation Studies as Topic | Databases, Chemical | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Protein Conformation | Isoenzymes - antagonists & inhibitors | Enzymes | Dehydroepiandrosterone | Corticosteroids | Bile acids | Estrogen | Cytochrome P-450 | Physiological aspects | Alcoholic beverages | Drug discovery | Retinoids | Progesterone | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Molecular Catalysis. B, Enzymatic, ISSN 1381-1177, 12/2015, Volume 122, pp. 179 - 187
ZJUY-1401 is capable of producing anti-Prelog alcohols with excellent stereoselectivity. The gene encoding a short-chain dehydrogenase/reductase from ZJUY-1401... 
Empedobacter brevis | Asymmetric reduction | Anti-Prelog | Cofactor regeneration | Short-chain dehydrogenase/reductase | CHEMISTRY, PHYSICAL | CARBONYL REDUCTASE | PROCHIRAL KETONES | ALCOHOL-DEHYDROGENASE | LACTOBACILLUS-BREVIS | PURIFICATION | CHIRAL ALCOHOLS | WHOLE CELLS | EXPRESSION | GENE CLONING
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2016, Volume 472, Issue 1, pp. 231 - 236
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 01/2014, Volume 207, Issue 1, pp. 52 - 57
Dehydrogenase/reductase (SDR family) member 7 (DHRS7, retSDR4, SDR34C1) is a previously uncharacterized member of the short-chain dehydrogenase/reductase (SDR)... 
Short-chain dehydrogenases/reductases | DHRS7 | SDR34C1 | Membrane topology | Oxidoreductase activity | Amino Acid Sequence | Nitrosamines - metabolism | Oxidoreductases - metabolism | Humans | Nitrosamines - chemistry |