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Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 10, pp. e77166 - e77166
Smooth muscle alpha actin (Acta2) expression is largely restricted to smooth muscle cells, pericytes and specialized fibroblasts, known as myofibroblasts.... 
FAT-STORING CELLS | SKELETAL-MUSCLE | GRANULATION-TISSUE | LIVER-INJURY | GAMMA-ACTIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | STELLATE CELLS | EXTRACELLULAR-MATRIX | FOCAL ADHESION KINASE | AMINO-ACID SEQUENCE | RNA, Small Interfering - genetics | Phosphorylation | Cell Proliferation | Embryo, Mammalian | Carbon Tetrachloride | Actins - metabolism | Hepatic Stellate Cells - metabolism | Male | Actins - genetics | Myofibroblasts - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Cell Differentiation | Wound Healing - genetics | Chemical and Drug Induced Liver Injury - pathology | Hepatic Stellate Cells - pathology | Myofibroblasts - pathology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Gene Expression Regulation | Rats | Chemical and Drug Induced Liver Injury - genetics | Rats, Sprague-Dawley | Actins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Chemical and Drug Induced Liver Injury - metabolism | Mice | Primary Cell Culture | Cell Movement | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Transformation | Motility | Liver | Amino acids | Smooth muscle | Contraction | Cell adhesion & migration | Proteins | Actin | Rodents | Hepatology | Fibroblasts | Drug dosages | Injuries | Stellate cells | Wound healing | Internal medicine | Muscles | Extracellular signal-regulated kinase | Cell division | Carbon | Cirrhosis | Signaling | Hepatocytes | Pericytes | Cytoskeleton | Healing | Transformations | Bile | Index Medicus
Journal Article
Neuromuscular Disorders, ISSN 0960-8966, 04/2018, Volume 28, Issue 4, pp. 323 - 326
We present here a Finnish nemaline myopathy family with a dominant mutation in the skeletal muscle α-actin gene, p.(Glu85Lys), segregating in three... 
Dominant inheritance | Skeletal muscle alpha-actin | Three-generation family | Clinical variability | Nemaline myopathy | Muscles | Genetic aspects | Genetic disorders | Muscle proteins | Actin | Genes
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2018, Volume 8, Issue 1, pp. 11490 - 12
L-tyrosine supplementation may provide benefit to nemaline myopathy (NM) patients, however previous studies are inconclusive, with no elevation of L-tyrosine... 
EXCESS TYROSINE | ACID | PROTEIN | RAT | MULTIDISCIPLINARY SCIENCES | DIETARY TYROSINE | TOXICITY | AGED MICE | PATHOLOGY | STRESS | Tyrosine | Energy metabolism | Animal models | Fertilization | Dietary supplements | Mechanical properties | Zebrafish | Skeletal muscle | Atrophy | Musculoskeletal system | Actin | Nemaline myopathy | Quadriceps muscle | Supplementation | Myopathy | Life Sciences
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 10/2007, Volume 101, Issue 9, pp. 883 - 892
There has been considerable controversy regarding the lineage relationship between smooth muscle cells (SMCs) and myofibroblasts, because they express a number... 
Transgenic mouse | Smooth muscle α-actin | MCAT elements | Transcriptional enhancer factor-1 | MYOCARDIN | CARDIAC & CARDIOVASCULAR SYSTEMS | ENHANCER FACTOR-I | DNA-BINDING PROTEINS | CARG | smooth muscle alpha-actin | transgenic mouse | transcriptional enhancer factor-1 | SERUM RESPONSE FACTOR | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | COFACTOR | DIFFERENTIATION | PROMOTER | HEMATOLOGY | MARKER GENES | Basic-Leucine Zipper Transcription Factors - metabolism | Fibroblasts - physiology | Heart - embryology | Heart - physiology | Male | Muscle, Skeletal - cytology | Actins - genetics | Muscle, Smooth, Vascular - embryology | DNA-Binding Proteins - metabolism | Muscle Proteins - metabolism | Antineoplastic Agents - pharmacology | Muscle, Skeletal - embryology | Cell Differentiation - physiology | Muscle, Smooth, Vascular - physiology | Transforming Growth Factor beta1 - pharmacology | Gene Expression Regulation, Developmental - physiology | Tretinoin - pharmacology | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Mice, Transgenic | Muscle, Skeletal - physiology | Muscle, Smooth, Vascular - cytology | Transcription Factors - metabolism | Phenotype | Transcription, Genetic - physiology | Animals | Promoter Regions, Genetic - physiology | Fibroblasts - cytology | Mice | Aorta - cytology | Lac Operon | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 03/2012, Volume 112, Issue 5, pp. 898 - 903
Shardonofsky FR, Moore J, Schwartz RJ, Boriek AM. Airways in smooth muscle alpha-actin null mice experience a compensatory mechanism that modulates their... 
Airway resistance | Lung mechanical stress | SM22 | Lung elastance | Mechanical ventilation | CELLS | SPORT SCIENCES | RESPONSIVENESS | PHYSIOLOGY | mechanical ventilation | STRETCH | POLYMERIZATION | lung elastance | DEEP INSPIRATION | lung mechanical stress | FREQUENCY | MYOFIBROBLASTS | ASTHMA | DIFFERENTIATION | airway resistance | EXPRESSION | Contractile Proteins - genetics | Respiration, Artificial - methods | Airway Resistance - drug effects | Muscle Contraction - genetics | Actins - metabolism | Muscle, Skeletal - metabolism | Smooth Muscle Myosins - drug effects | Airway Resistance - genetics | Smooth Muscle Myosins - genetics | Actins - genetics | Methacholine Chloride - pharmacology | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Smooth Muscle Myosins - metabolism | Muscle, Smooth - physiology | Lung - metabolism | Microfilament Proteins - metabolism | Contractile Proteins - metabolism | Myocytes, Smooth Muscle - drug effects | Microfilament Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Smooth Muscle Myosins - physiology | Mice, Inbred C57BL | RNA, Messenger - genetics | Myocytes, Smooth Muscle - physiology | Muscle, Skeletal - physiology | Muscle, Smooth - metabolism | Lung - physiology | Mice, Knockout | Muscle Proteins - genetics | Animals | Muscle Contraction - drug effects | Lung - drug effects | Muscle Contraction - physiology | Airway Resistance - physiology | Mice | Index Medicus
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 04/1999, Volume 84, Issue 7, pp. 852 - 861
The aims of the present studies were to define sufficient promoter sequences required to drive endogenous expression of smooth muscle (SM) alpha-actin and to... 
Transfection | Gene expression | Muscle, smooth | Transgenic mice | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | muscle, smooth | transfection | HEAVY-CHAIN GENE | TRANSCRIPTION | DNA-BINDING PROTEINS | MYOBLASTS | CIS |