American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2016, Volume 214, Issue 3, pp. 356.e1 - 356.e15
Background Preeclampsia is associated with placental ischemia/hypoxia and secretion of soluble fms-like tyrosine kinase 1 and soluble endoglin into the...
Obstetrics and Gynecology | soluble fms-like tyrosine kinase 1 | metformin | electron transport chain | preeclampsia | soluble endoglin | NORMAL-PREGNANCY | ADHESION MOLECULES | HYPOXIA | ANGIOGENIC FACTORS | GUANYLATE-CYCLASE | OBSTETRICS & GYNECOLOGY | WOMEN | HYPERTENSION | EXPRESSION | PLACENTAL MITOCHONDRIAL CONTENT | SFLT-1 | Metformin - therapeutic use | Humans | Endothelium, Vascular - drug effects | Pre-Eclampsia - physiopathology | Antigens, CD - metabolism | Endoglin | Pre-Eclampsia - prevention & control | Female | Pre-Eclampsia - metabolism | Biomarkers - metabolism | Metformin - pharmacology | Endothelium, Vascular - physiopathology | Receptors, Cell Surface - metabolism | Treatment Outcome | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Cardiovascular Agents - pharmacology | Placenta - drug effects | Placenta - metabolism | Pregnancy | Cardiovascular Agents - therapeutic use | Pre-Eclampsia - drug therapy | Endothelium, Vascular - metabolism | Electron Transport Chain Complex Proteins - metabolism | Vasodilation - drug effects | In Vitro Techniques | Hypertension | Prevention | Tyrosine | Care and treatment | Preeclampsia | Phenols | Metformin | Diabetes therapy | Endothelium | Analysis
Obstetrics and Gynecology | soluble fms-like tyrosine kinase 1 | metformin | electron transport chain | preeclampsia | soluble endoglin | NORMAL-PREGNANCY | ADHESION MOLECULES | HYPOXIA | ANGIOGENIC FACTORS | GUANYLATE-CYCLASE | OBSTETRICS & GYNECOLOGY | WOMEN | HYPERTENSION | EXPRESSION | PLACENTAL MITOCHONDRIAL CONTENT | SFLT-1 | Metformin - therapeutic use | Humans | Endothelium, Vascular - drug effects | Pre-Eclampsia - physiopathology | Antigens, CD - metabolism | Endoglin | Pre-Eclampsia - prevention & control | Female | Pre-Eclampsia - metabolism | Biomarkers - metabolism | Metformin - pharmacology | Endothelium, Vascular - physiopathology | Receptors, Cell Surface - metabolism | Treatment Outcome | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Cardiovascular Agents - pharmacology | Placenta - drug effects | Placenta - metabolism | Pregnancy | Cardiovascular Agents - therapeutic use | Pre-Eclampsia - drug therapy | Endothelium, Vascular - metabolism | Electron Transport Chain Complex Proteins - metabolism | Vasodilation - drug effects | In Vitro Techniques | Hypertension | Prevention | Tyrosine | Care and treatment | Preeclampsia | Phenols | Metformin | Diabetes therapy | Endothelium | Analysis
Journal Article
BJOG: An International Journal of Obstetrics & Gynaecology, ISSN 1470-0328, 06/2012, Volume 119, Issue 7, pp. 778 - 787
Please cite this paper as: Kleinrouweler C, Wiegerinck M, Ris‐Stalpers C, Bossuyt P, van der Post J, von Dadelszen P, Mol B, Pajkrt E, for the EBM CONNECT...
placental growth factor | Biomarkers | pre‐eclampsia | vascular endothelial growth factor | soluble endoglin | soluble fms‐like tyrosine kinase‐1 | pre-eclampsia | soluble fms-like tyrosine kinase-1 | HYPERTENSIVE DISORDERS | PROSPECTIVE COHORT | OBSTETRICS & GYNECOLOGY | UTERINE ARTERY DOPPLER | ANTIANGIOGENIC FACTORS | ACTIVIN-A | EARLY-ONSET PREECLAMPSIA | EARLY-PREGNANCY | MATERNAL PLASMA | SERUM-LEVELS | ANGIOGENESIS-RELATED FACTORS | Humans | Receptors, Cell Surface - blood | Biomarkers - blood | Pregnancy | Endoglin | Pregnancy Proteins - blood | Antigens, CD - blood | Pre-Eclampsia - blood | Sensitivity and Specificity | Vascular Endothelial Growth Factors - blood | Placenta Growth Factor | Female | Odds Ratio | Vascular Endothelial Growth Factor Receptor-1 - blood | Pre-Eclampsia - diagnosis
placental growth factor | Biomarkers | pre‐eclampsia | vascular endothelial growth factor | soluble endoglin | soluble fms‐like tyrosine kinase‐1 | pre-eclampsia | soluble fms-like tyrosine kinase-1 | HYPERTENSIVE DISORDERS | PROSPECTIVE COHORT | OBSTETRICS & GYNECOLOGY | UTERINE ARTERY DOPPLER | ANTIANGIOGENIC FACTORS | ACTIVIN-A | EARLY-ONSET PREECLAMPSIA | EARLY-PREGNANCY | MATERNAL PLASMA | SERUM-LEVELS | ANGIOGENESIS-RELATED FACTORS | Humans | Receptors, Cell Surface - blood | Biomarkers - blood | Pregnancy | Endoglin | Pregnancy Proteins - blood | Antigens, CD - blood | Pre-Eclampsia - blood | Sensitivity and Specificity | Vascular Endothelial Growth Factors - blood | Placenta Growth Factor | Female | Odds Ratio | Vascular Endothelial Growth Factor Receptor-1 - blood | Pre-Eclampsia - diagnosis
Journal Article
Kidney International, ISSN 0085-2538, 05/2019, Volume 95, Issue 5, pp. 1091 - 1102
Renal ischemia reperfusion injury (IRI) adversely affects clinical outcomes following kidney transplantation. Understanding the cellular mechanisms and the...
soluble fms-like tyrosine kinase 1 | microvascular dysfunction | clinical outcomes | ischemia-reperfusion
soluble fms-like tyrosine kinase 1 | microvascular dysfunction | clinical outcomes | ischemia-reperfusion
Journal Article
Hypertension, ISSN 0194-911X, 02/2012, Volume 59, Issue 2, pp. 256 - 264
The cardinal manifestations of the pregnancy-specific disorder preeclampsia, new-onset hypertension, and proteinuria that resolve with placental delivery have...
Syncytial aggregates | SFlt1 | Preeclampsia | Microparticles | Syncytial knots | Soluble VEGFR1 | sFlt1 | NORMAL-PREGNANCY | HEPARIN-BINDING | soluble VEGFR1 | microparticles | SYNCYTIOTROPHOBLAST MICROPARTICLES | preeclampsia | FLT-1 | syncytial knots | PLASMA | REDUCTION | PLACENTAL EXPRESSION | PERIPHERAL VASCULAR DISEASE | syncytial aggregates | TROPHOBLAST DEPORTATION | PROTEINS | GROWTH-FACTOR RECEPTOR-1 | Humans | Pregnancy Complications, Hematologic - blood | Cells, Cultured | Pregnancy | Pregnancy Proteins - blood | RNA, Messenger - blood | Placenta - cytology | Pre-Eclampsia - blood | Cell-Derived Microparticles - pathology | Female | Pregnancy Trimester, Third - blood | Trophoblasts - cytology | Vascular Endothelial Growth Factor Receptor-1 - blood | Organ Culture Techniques
Syncytial aggregates | SFlt1 | Preeclampsia | Microparticles | Syncytial knots | Soluble VEGFR1 | sFlt1 | NORMAL-PREGNANCY | HEPARIN-BINDING | soluble VEGFR1 | microparticles | SYNCYTIOTROPHOBLAST MICROPARTICLES | preeclampsia | FLT-1 | syncytial knots | PLASMA | REDUCTION | PLACENTAL EXPRESSION | PERIPHERAL VASCULAR DISEASE | syncytial aggregates | TROPHOBLAST DEPORTATION | PROTEINS | GROWTH-FACTOR RECEPTOR-1 | Humans | Pregnancy Complications, Hematologic - blood | Cells, Cultured | Pregnancy | Pregnancy Proteins - blood | RNA, Messenger - blood | Placenta - cytology | Pre-Eclampsia - blood | Cell-Derived Microparticles - pathology | Female | Pregnancy Trimester, Third - blood | Trophoblasts - cytology | Vascular Endothelial Growth Factor Receptor-1 - blood | Organ Culture Techniques
Journal Article
KIDNEY INTERNATIONAL, ISSN 0085-2538, 05/2019, Volume 95, Issue 5, pp. 1091 - 1102
Renal ischemia reperfusion injury (IRI) adversely affects clinical outcomes following kidney transplantation. Understanding the cellular mechanisms and the...
soluble fms-like tyrosine kinase 1 | FACTOR VEGF | ACTIVATION | DELAYED GRAFT FUNCTION | INJURY | RECEPTOR | ischemia-reperfusion | FLT-1 | microvascular dysfunction | clinical outcomes | PERITUBULAR CAPILLARIES | UROLOGY & NEPHROLOGY | DYSFUNCTION | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR
soluble fms-like tyrosine kinase 1 | FACTOR VEGF | ACTIVATION | DELAYED GRAFT FUNCTION | INJURY | RECEPTOR | ischemia-reperfusion | FLT-1 | microvascular dysfunction | clinical outcomes | PERITUBULAR CAPILLARIES | UROLOGY & NEPHROLOGY | DYSFUNCTION | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Hypertension, ISSN 0194-911X, 11/2011, Volume 58, Issue 5, pp. 859 - 866
It has not been clarified whether thresholds of soluble fms-like tyrosine kinase 1 (sFlt-1), placental growth factor (PlGF), soluble endoglin, and the...
Soluble fms-like tyrosine kinase 1 | Soluble endoglin | Placental growth factor | Preeclampsia | Prospective cohort study | Prediction | soluble fms-like tyrosine kinase 1 | RISK-FACTORS | prospective cohort study | ENDOGLIN | preeclampsia | RESTRICTION | CIRCULATING ANTIANGIOGENIC FACTORS | PREGNANCY | placental growth factor | UTERINE ARTERY DOPPLER | WOMEN | GESTATIONAL HYPERTENSION | CLINICAL-MANIFESTATIONS | prediction | PERIPHERAL VASCULAR DISEASE | ANGIOGENESIS-RELATED FACTORS | soluble endoglin | Risk Assessment | Humans | Japan | Reference Values | Biomarkers - blood | Gestational Age | Pre-Eclampsia - physiopathology | Case-Control Studies | Pregnancy | Pregnancy Proteins - blood | Time Factors | Pre-Eclampsia - blood | Sensitivity and Specificity | Placenta Growth Factor | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Pregnancy Outcome
Soluble fms-like tyrosine kinase 1 | Soluble endoglin | Placental growth factor | Preeclampsia | Prospective cohort study | Prediction | soluble fms-like tyrosine kinase 1 | RISK-FACTORS | prospective cohort study | ENDOGLIN | preeclampsia | RESTRICTION | CIRCULATING ANTIANGIOGENIC FACTORS | PREGNANCY | placental growth factor | UTERINE ARTERY DOPPLER | WOMEN | GESTATIONAL HYPERTENSION | CLINICAL-MANIFESTATIONS | prediction | PERIPHERAL VASCULAR DISEASE | ANGIOGENESIS-RELATED FACTORS | soluble endoglin | Risk Assessment | Humans | Japan | Reference Values | Biomarkers - blood | Gestational Age | Pre-Eclampsia - physiopathology | Case-Control Studies | Pregnancy | Pregnancy Proteins - blood | Time Factors | Pre-Eclampsia - blood | Sensitivity and Specificity | Placenta Growth Factor | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Pregnancy Outcome
Journal Article
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 05/2015, Volume 45, Issue 5, pp. 584 - 590
ABSTRACT Objective To define the contribution of maternal variables which influence the measured level of maternal serum soluble fms‐like tyrosine kinase‐1...
pyramid of pregnancy care | sFlt‐1 | second‐trimester screening | trisomy 21 | third‐trimester screening | pre‐eclampsia | soluble fms‐like tyrosine kinase‐1 | first‐trimester screening | third-trimester screening | sFlt-1 | second-trimester screening | first-trimester screening | pre-eclampsia | soluble fms-like tyrosine kinase-1 | RISK | ANGIOGENIC FACTORS | OBSTETRICS & GYNECOLOGY | ACOUSTICS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Body Mass Index | Medical History Taking | Predictive Value of Tests | Prospective Studies | Humans | United Kingdom | Biomarkers - blood | Gestational Age | Pregnancy | Pregnancy Proteins - blood | Sensitivity and Specificity | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Pregnancy Trimesters | Pregnancy Outcome | Tyrosine | Phenols | Pregnant women | Analysis | Smoking | Medical research | Birth weight
pyramid of pregnancy care | sFlt‐1 | second‐trimester screening | trisomy 21 | third‐trimester screening | pre‐eclampsia | soluble fms‐like tyrosine kinase‐1 | first‐trimester screening | third-trimester screening | sFlt-1 | second-trimester screening | first-trimester screening | pre-eclampsia | soluble fms-like tyrosine kinase-1 | RISK | ANGIOGENIC FACTORS | OBSTETRICS & GYNECOLOGY | ACOUSTICS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Body Mass Index | Medical History Taking | Predictive Value of Tests | Prospective Studies | Humans | United Kingdom | Biomarkers - blood | Gestational Age | Pregnancy | Pregnancy Proteins - blood | Sensitivity and Specificity | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Pregnancy Trimesters | Pregnancy Outcome | Tyrosine | Phenols | Pregnant women | Analysis | Smoking | Medical research | Birth weight
Journal Article
Placenta, ISSN 0143-4004, 2014, Volume 35, Issue 7, pp. 476 - 482
Abstract Objective To investigate the effects of edaravone, a potent free radical scavenger used clinically, on hypoxia-induced trophoblast-soluble Fms-like...
Internal Medicine | Obstetrics and Gynecology | Hypoxia | Trophoblasts | Edaravone | Preeclampsia | Soluble Fms-like tyrosine kinase 1 (sFlt-1) | OXIDATIVE STRESS | INDUCIBLE FACTOR | ACUTE LIVER-INJURY | FREE-RADICAL SCAVENGER | DEVELOPMENTAL BIOLOGY | SPIRAL ARTERIES | CELL-DEATH | OBSTETRICS & GYNECOLOGY | OXYGEN | IN-VITRO | REPRODUCTIVE BIOLOGY | ERYTHROPOIETIN GENE | GROWTH-FACTOR RECEPTOR-1 | Free Radical Scavengers - pharmacology | Human Umbilical Vein Endothelial Cells | Pre-Eclampsia - genetics | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Gene Expression - drug effects | Antipyrine - pharmacology | Humans | Pregnancy Proteins - genetics | Pregnancy Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Trophoblasts - drug effects | Antipyrine - analogs & derivatives | Female | Pre-Eclampsia - metabolism | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Line | Cell Hypoxia - drug effects | Trophoblasts - metabolism | RNA, Messenger - genetics | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Pregnancy | Cobalt - toxicity | Pre-Eclampsia - drug therapy | Placenta Growth Factor | Tyrosine | Phenols | Health aspects
Internal Medicine | Obstetrics and Gynecology | Hypoxia | Trophoblasts | Edaravone | Preeclampsia | Soluble Fms-like tyrosine kinase 1 (sFlt-1) | OXIDATIVE STRESS | INDUCIBLE FACTOR | ACUTE LIVER-INJURY | FREE-RADICAL SCAVENGER | DEVELOPMENTAL BIOLOGY | SPIRAL ARTERIES | CELL-DEATH | OBSTETRICS & GYNECOLOGY | OXYGEN | IN-VITRO | REPRODUCTIVE BIOLOGY | ERYTHROPOIETIN GENE | GROWTH-FACTOR RECEPTOR-1 | Free Radical Scavengers - pharmacology | Human Umbilical Vein Endothelial Cells | Pre-Eclampsia - genetics | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Gene Expression - drug effects | Antipyrine - pharmacology | Humans | Pregnancy Proteins - genetics | Pregnancy Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Trophoblasts - drug effects | Antipyrine - analogs & derivatives | Female | Pre-Eclampsia - metabolism | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Line | Cell Hypoxia - drug effects | Trophoblasts - metabolism | RNA, Messenger - genetics | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Pregnancy | Cobalt - toxicity | Pre-Eclampsia - drug therapy | Placenta Growth Factor | Tyrosine | Phenols | Health aspects
Journal Article
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2006, Volume 195, Issue 1, pp. 255 - 259
The purpose of this study was to determine if maternal serum concentrations of placenta growth factor (PlGF) and soluble Fms-like tyrosine kinase 1 receptor...
Pregnancy | Soluble Fms-like tyrosine kinase 1 receptor (s-Flt1) | Placenta growth factor (PlGF) | Preeclampsia | placenta growth factor (PIGF) | soluble Fms-like tyrosine kinase 1 receptor (s-Flt1) | RECEPTOR-BINDING PROPERTIES | ENDOTHELIAL DYSFUNCTION | pregnancy | SERUM-LEVELS | MECHANISMS | preeclampsia | EXPRESSION | OBSTETRICS & GYNECOLOGY | Pregnancy Proteins - blood | Enzyme-Linked Immunosorbent Assay | Humans | Pre-Eclampsia - blood | Placenta Growth Factor | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Gestational Age | Pre-Eclampsia - physiopathology | Tyrosine | Phenols | Growth factors | Analysis
Pregnancy | Soluble Fms-like tyrosine kinase 1 receptor (s-Flt1) | Placenta growth factor (PlGF) | Preeclampsia | placenta growth factor (PIGF) | soluble Fms-like tyrosine kinase 1 receptor (s-Flt1) | RECEPTOR-BINDING PROPERTIES | ENDOTHELIAL DYSFUNCTION | pregnancy | SERUM-LEVELS | MECHANISMS | preeclampsia | EXPRESSION | OBSTETRICS & GYNECOLOGY | Pregnancy Proteins - blood | Enzyme-Linked Immunosorbent Assay | Humans | Pre-Eclampsia - blood | Placenta Growth Factor | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Gestational Age | Pre-Eclampsia - physiopathology | Tyrosine | Phenols | Growth factors | Analysis
Journal Article
Hypertension, ISSN 0194-911X, 12/2018, Volume 72, Issue 6, pp. 1381 - 1390
Preeclampsia is a unique multiple system disorder that affects 5% to 8% of pregnancies. Exosomes, membrane-encapsulated vesicles that are released into the...
Endoglin | Soluble | Flt1, soluble | Flt1 | Soluble preeclampsia | exosomes | pregnancy | endoglin, soluble | preeclampsia | CONTRIBUTE | METASTASIS | ANGIOGENESIS | MECHANISM | soluble | RECEPTOR | endoglin | PLACENTAL EXOSOMES | CANCER | DEBRIS | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | Tyrosine | Women | Complications and side effects | Blood circulation disorders | Preeclampsia | Research | Health aspects | Risk factors | Endothelium
Endoglin | Soluble | Flt1, soluble | Flt1 | Soluble preeclampsia | exosomes | pregnancy | endoglin, soluble | preeclampsia | CONTRIBUTE | METASTASIS | ANGIOGENESIS | MECHANISM | soluble | RECEPTOR | endoglin | PLACENTAL EXOSOMES | CANCER | DEBRIS | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | Tyrosine | Women | Complications and side effects | Blood circulation disorders | Preeclampsia | Research | Health aspects | Risk factors | Endothelium
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2017, Volume 18, Issue 4, pp. 753 - 753
In severe acute pancreatitis (SAP), systemic inflammation leads to endothelial dysfunction and activation of coagulation. Thrombotic disorders in acute...
D-dimer | Angiopoietin-2 | Disseminated intravascular coagulation | Soluble fms-like tyrosine kinase 1 | Acute pancreatitis | angiopoietin-2 | soluble fms-like tyrosine kinase 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, MULTIDISCIPLINARY | SPLANCHNIC VEIN-THROMBOSIS | ORGAN-FAILURE | SINGLE-CENTER-EXPERIENCE | EARLY SEPSIS | PRETREATMENT | INFLAMMATION | acute pancreatitis | CLINICAL-IMPLICATIONS | disseminated intravascular coagulation | ACENOCOUMAROL | Severity of Illness Index | Acute Disease | Prognosis | Prospective Studies | Fibrin Fibrinogen Degradation Products - metabolism | Humans | Middle Aged | Solubility | Logistic Models | Male | Biomarkers - blood | Pancreatitis - complications | C-Reactive Protein - metabolism | Aged, 80 and over | Blood Coagulation Disorders - blood | Female | Aged | Blood Coagulation Disorders - diagnosis | Vascular Endothelial Growth Factor Receptor-1 - blood | Angiopoietin-2 - blood | Blood Coagulation Disorders - complications | Tyrosine | C-reactive protein | Angiopoietin | Abnormalities | Coagulation | Markers | Pancreatitis | Disorders | Inflammation | Kinases | SAP protein | Patients | Thrombosis | Clotting | Hemostasis | Fibrinogen | Dimers | Hemostatics | Pancreas | Protein-tyrosine kinase
D-dimer | Angiopoietin-2 | Disseminated intravascular coagulation | Soluble fms-like tyrosine kinase 1 | Acute pancreatitis | angiopoietin-2 | soluble fms-like tyrosine kinase 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, MULTIDISCIPLINARY | SPLANCHNIC VEIN-THROMBOSIS | ORGAN-FAILURE | SINGLE-CENTER-EXPERIENCE | EARLY SEPSIS | PRETREATMENT | INFLAMMATION | acute pancreatitis | CLINICAL-IMPLICATIONS | disseminated intravascular coagulation | ACENOCOUMAROL | Severity of Illness Index | Acute Disease | Prognosis | Prospective Studies | Fibrin Fibrinogen Degradation Products - metabolism | Humans | Middle Aged | Solubility | Logistic Models | Male | Biomarkers - blood | Pancreatitis - complications | C-Reactive Protein - metabolism | Aged, 80 and over | Blood Coagulation Disorders - blood | Female | Aged | Blood Coagulation Disorders - diagnosis | Vascular Endothelial Growth Factor Receptor-1 - blood | Angiopoietin-2 - blood | Blood Coagulation Disorders - complications | Tyrosine | C-reactive protein | Angiopoietin | Abnormalities | Coagulation | Markers | Pancreatitis | Disorders | Inflammation | Kinases | SAP protein | Patients | Thrombosis | Clotting | Hemostasis | Fibrinogen | Dimers | Hemostatics | Pancreas | Protein-tyrosine kinase
Journal Article
American Journal of Reproductive Immunology, ISSN 1046-7408, 11/2018, Volume 80, Issue 5, pp. e13034 - n/a
Problem A handful of studies report sexual dimorphism in the maternal angiogenic profile possibly influencing placental development and preeclampsia risk. This...
fetal sex | soluble fms‐like tyrosine kinase 1 | preeclampsia | pregnancy | soluble fms-like tyrosine kinase 1 | PLACENTA | RISK | MODEL | IMMUNOLOGY | ANGIOGENIC FACTORS | BIOMARKERS | REPRODUCTIVE BIOLOGY | ADAM12 | COHORT | MATERNAL ASTHMA | GROWTH-FACTOR | Tyrosine | Statistical analysis | Fetuses | Sex | Dimorphism | Pre-eclampsia | Generalized linear models | Gestational age | Pregnancy | Angiogenesis | Endoglin | Body mass index | Placenta | Preeclampsia | Biomarkers | Blood pressure | Sexual dimorphism | Protein-tyrosine kinase | Smoking | Proteinuria
fetal sex | soluble fms‐like tyrosine kinase 1 | preeclampsia | pregnancy | soluble fms-like tyrosine kinase 1 | PLACENTA | RISK | MODEL | IMMUNOLOGY | ANGIOGENIC FACTORS | BIOMARKERS | REPRODUCTIVE BIOLOGY | ADAM12 | COHORT | MATERNAL ASTHMA | GROWTH-FACTOR | Tyrosine | Statistical analysis | Fetuses | Sex | Dimorphism | Pre-eclampsia | Generalized linear models | Gestational age | Pregnancy | Angiogenesis | Endoglin | Body mass index | Placenta | Preeclampsia | Biomarkers | Blood pressure | Sexual dimorphism | Protein-tyrosine kinase | Smoking | Proteinuria
Journal Article
Hypertension, ISSN 0194-911X, 11/2009, Volume 54, Issue 5, pp. 1129 - 1135
The first aim of our study was to develop a pregnant mouse model for preeclampsia using adenoviral vector containing mouse full-length soluble fms-like...
Therapy | Animal models | Preeclampsia | Adenoviral vector | Soluble fms-like tyrosine kinase 1 | Placental growth factor | Vascular endothelial growth factor | soluble fms-like tyrosine kinase 1 | FACTOR VEGF | FLT-1 GENE | animal models | RAT | BEVACIZUMAB | therapy | SEVERE PREECLAMPSIA | EXTRACELLULAR DOMAIN | RANDOMIZED-TRIAL | RECEPTOR | adenoviral vector | preeclampsia | METASTATIC COLORECTAL-CANCER | placental growth factor | ANTIANGIOGENIC FACTORS | vascular endothelial growth factor | PERIPHERAL VASCULAR DISEASE | Pregnancy, Animal | Pre-Eclampsia - chemically induced | Humans | Probability | Hypertension - drug therapy | Reference Values | Membrane Proteins - pharmacology | Random Allocation | Mice, Inbred Strains | Pregnancy Proteins - pharmacology | Pregnancy | Animals | Pre-Eclampsia - drug therapy | Hypertension - chemically induced | Adenoviridae - genetics | Placenta Growth Factor | Female | Mice | Genetic Vectors | Vascular Endothelial Growth Factor A - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - pharmacology | Disease Models, Animal | Proteinuria | Index Medicus
Therapy | Animal models | Preeclampsia | Adenoviral vector | Soluble fms-like tyrosine kinase 1 | Placental growth factor | Vascular endothelial growth factor | soluble fms-like tyrosine kinase 1 | FACTOR VEGF | FLT-1 GENE | animal models | RAT | BEVACIZUMAB | therapy | SEVERE PREECLAMPSIA | EXTRACELLULAR DOMAIN | RANDOMIZED-TRIAL | RECEPTOR | adenoviral vector | preeclampsia | METASTATIC COLORECTAL-CANCER | placental growth factor | ANTIANGIOGENIC FACTORS | vascular endothelial growth factor | PERIPHERAL VASCULAR DISEASE | Pregnancy, Animal | Pre-Eclampsia - chemically induced | Humans | Probability | Hypertension - drug therapy | Reference Values | Membrane Proteins - pharmacology | Random Allocation | Mice, Inbred Strains | Pregnancy Proteins - pharmacology | Pregnancy | Animals | Pre-Eclampsia - drug therapy | Hypertension - chemically induced | Adenoviridae - genetics | Placenta Growth Factor | Female | Mice | Genetic Vectors | Vascular Endothelial Growth Factor A - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - pharmacology | Disease Models, Animal | Proteinuria | Index Medicus
Journal Article
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2007, Volume 197, Issue 1, pp. 28.e1 - 28.e6
The objective of this pilot study was to evaluate the clinical utility of soluble fms-like tyrosine kinase 1 (sFlt 1) and soluble endoglin (sEng) in the...
soluble fms-like tyrosine kinase 1 | preeclampsia | hypertension in pregnancy | soluble endoglin | WOMEN | PLACENTAL GROWTH-FACTOR | OBSTETRICS & GYNECOLOGY | Diagnosis, Differential | Hypertension, Pregnancy-Induced - blood | Humans | Receptors, Cell Surface - blood | Hypertension, Pregnancy-Induced - diagnosis | Pre-Eclampsia - physiopathology | Pregnancy Trimester, Third | Case-Control Studies | Placenta - metabolism | Pregnancy | Endoglin | Antigens, CD - blood | Pilot Projects | Pre-Eclampsia - blood | Sensitivity and Specificity | Adult | Female | Pregnancy Complications, Cardiovascular - diagnosis | Vascular Endothelial Growth Factor Receptor-1 - blood | Pre-Eclampsia - diagnosis | Pregnancy Complications, Cardiovascular - blood | Hypertension | Pregnant women | Diagnosis
soluble fms-like tyrosine kinase 1 | preeclampsia | hypertension in pregnancy | soluble endoglin | WOMEN | PLACENTAL GROWTH-FACTOR | OBSTETRICS & GYNECOLOGY | Diagnosis, Differential | Hypertension, Pregnancy-Induced - blood | Humans | Receptors, Cell Surface - blood | Hypertension, Pregnancy-Induced - diagnosis | Pre-Eclampsia - physiopathology | Pregnancy Trimester, Third | Case-Control Studies | Placenta - metabolism | Pregnancy | Endoglin | Antigens, CD - blood | Pilot Projects | Pre-Eclampsia - blood | Sensitivity and Specificity | Adult | Female | Pregnancy Complications, Cardiovascular - diagnosis | Vascular Endothelial Growth Factor Receptor-1 - blood | Pre-Eclampsia - diagnosis | Pregnancy Complications, Cardiovascular - blood | Hypertension | Pregnant women | Diagnosis
Journal Article
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 03/2016, Volume 47, Issue 3, pp. 324 - 331
ABSTRACT Objectives To investigate longitudinal changes in maternal serum levels of placental growth factor (PlGF) and soluble fms‐like tyrosine kinase‐1...
gestational hypertension | placental growth factor | blood pressure | pregnancy screening | pre‐eclampsia | soluble fms‐like tyrosine kinase‐1 | pre-eclampsia | soluble fms-like tyrosine kinase-1 | ENDOGLIN | ANGIOGENIC FACTORS | PREGNANCY | PREDICTION | OBSTETRICS & GYNECOLOGY | ACOUSTICS | PLASMA | ABNORMAL PLACENTATION | MOUSE MODEL | SUSPECTED PREECLAMPSIA | HYPERTENSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | FOR-GESTATIONAL-AGE | Prospective Studies | Hypertension, Pregnancy-Induced - blood | Humans | Placenta Growth Factor - blood | Biomarkers - blood | Gestational Age | Pregnancy | Pre-Eclampsia - blood | Sensitivity and Specificity | Adult | Female | Pregnancy Trimester, Second - blood | Vascular Endothelial Growth Factor Receptor-1 - blood | Early Diagnosis | Longitudinal Studies | Hypertension | Tyrosine | Phenols | Pregnant women | Preeclampsia
gestational hypertension | placental growth factor | blood pressure | pregnancy screening | pre‐eclampsia | soluble fms‐like tyrosine kinase‐1 | pre-eclampsia | soluble fms-like tyrosine kinase-1 | ENDOGLIN | ANGIOGENIC FACTORS | PREGNANCY | PREDICTION | OBSTETRICS & GYNECOLOGY | ACOUSTICS | PLASMA | ABNORMAL PLACENTATION | MOUSE MODEL | SUSPECTED PREECLAMPSIA | HYPERTENSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | FOR-GESTATIONAL-AGE | Prospective Studies | Hypertension, Pregnancy-Induced - blood | Humans | Placenta Growth Factor - blood | Biomarkers - blood | Gestational Age | Pregnancy | Pre-Eclampsia - blood | Sensitivity and Specificity | Adult | Female | Pregnancy Trimester, Second - blood | Vascular Endothelial Growth Factor Receptor-1 - blood | Early Diagnosis | Longitudinal Studies | Hypertension | Tyrosine | Phenols | Pregnant women | Preeclampsia
Journal Article