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Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 4578 - 13
.... Here the authors use an inducible system to ablate microglia in adulthood, showing that such depletion leads to ataxia-like behavior and neuronal loss... 
FRACTALKINE RECEPTOR | MULTIPLE-SCLEROSIS | ADULT BRAIN | RNA-SEQ | AICARDI-GOUTIERES SYNDROME | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SYNAPSE FORMATION | CENTRAL-NERVOUS-SYSTEM | INTERFERON-BETA | MYELOID CELLS | Immunohistochemistry | Neurons - pathology | Minocycline - pharmacology | Cell Death - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Homeostasis | Gene Expression Profiling | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Receptor, Interferon alpha-beta - antagonists & inhibitors | Somatosensory Cortex - pathology | Flow Cytometry | Microglia - immunology | Somatosensory Cortex - immunology | Ataxia - pathology | Ataxia - immunology | Encephalomyelitis, Autoimmune, Experimental - pathology | Gray Matter - immunology | Neurons - immunology | Interferon Regulatory Factor-7 - immunology | Microscopy, Confocal | Rotarod Performance Test | Animals | Gray Matter - pathology | Anti-Bacterial Agents - pharmacology | Mice | Repopulation | Synaptogenesis | Central nervous system | Cortex (somatosensory) | Lymphocytes T | Inflammation | Substantia grisea | Ablation | Somatosensory system | Experimental allergic encephalomyelitis | Microglia | Interferon regulatory factor 7 | Cytometry | Depletion | Neurodegeneration | Minocycline | Neural stem cells | Ataxia | Interferon | Interferon regulatory factor
Journal Article