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The New England Journal of Medicine, ISSN 0028-4793, 10/2016, Volume 375, Issue 16, pp. 1532 - 1543
Journal Article
Journal of Clinical Periodontology, ISSN 0303-6979, 06/2018, Volume 45, Issue S19, pp. 11 - 12
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 02/2018, Volume 33, Issue 2, pp. 307 - 315
Journal Article
Biomaterials, ISSN 0142-9612, 06/2012, Volume 33, Issue 17, pp. 4251 - 4263
Wear particles are the major cause of osteolysis associated with failure of implant following total joint replacement. During this pathologic process,... 
Particle | SOST | BMP | Osteolysis | TNFandalpha | WNT
Journal Article
JOURNAL OF BONE AND MINERAL RESEARCH, ISSN 0884-0431, 01/2007, Volume 22, Issue 1, pp. 19 - 28
Sclerostin is an osteocyte-derived negative regulator of bone formation. It inhibits BMP-stimulated bone formation both in vitro and in vivo but has no direct... 
ANTAGONIST | BMP | INCREASED EXPRESSION | signal transduction | IDENTIFICATION | sclerostin | DENSITY | microarray | SOST GENE | MASS | ENDOCRINOLOGY & METABOLISM | RECEPTOR-RELATED PROTEIN-5 | KS483 CELLS | bone formation | SOST | DIFFERENTIATION | Wnt | VAN-BUCHEM-DISEASE
Journal Article
Bone, ISSN 8756-3282, 2013, Volume 54, Issue 2, pp. 244 - 249
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2009, Volume 24, Issue 4, pp. 578 - 588
The development of bone-rebuilding anabolic agents for potential use in the treatment of bone loss conditions, such as osteoporosis, has been a long-standing... 
Journal Article
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 02/2012, Volume 27, Issue 2, pp. 374 - 389
Journal Article
JOURNAL OF BONE AND MINERAL RESEARCH, ISSN 0884-0431, 06/2008, Volume 23, Issue 6, pp. 860 - 869
Introduction: Sclerosteosis is a rare high bone mass genetic disorder in humans caused by inactivating mutations in SOST, the gene encoding sclerostin. Based... 
PROTEIN | 17Q12-Q21 | sclerosteosis | sclerostin | DENSITY | LRP5 GENE | HISTOMORPHOMETRY | BMP ANTAGONIST | MASS | ENDOCRINOLOGY & METABOLISM | bone formation | SOST | MUTATIONS | bone strength | VAN-BUCHEM-DISEASE
Journal Article
by Zhang, DD and Park, BM and Kang, M and Nam, H and Kim, EJ and Bae, C and Lim, SK
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 04/2016, Volume 472, Issue 3, pp. 471 - 476
Sclerostin, encoded by the Sost gene, is mainly produced by osteocytes in bone and antagonizes the Wnt/beta-catenin signaling pathway, which is a requisite for... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOMIC INTEGRATION | LRP4 | Serum sclerostin | DELETION | FRACTURE | BIOPHYSICS | BONE-FORMATION | SOST GENE | ROMOSOZUMAB | Phi C31 integrase | Sost | Bone | MUTATIONS | POSTMENOPAUSAL WOMEN
Journal Article
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2003, Volume 22, Issue 23, pp. 6267 - 6276
Journal Article