X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6469) 6469
Newsletter (1215) 1215
Publication (1082) 1082
Book Review (98) 98
Book Chapter (83) 83
Newspaper Article (37) 37
Conference Proceeding (24) 24
Dissertation (17) 17
Government Document (6) 6
Magazine Article (2) 2
Book / eBook (1) 1
Data Set (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
sphingosine 1-phosphate (3679) 3679
index medicus (3074) 3074
animals (3069) 3069
sphingosine (3031) 3031
humans (2949) 2949
sphingosine - analogs & derivatives (2851) 2851
sphingosine-1-phosphate (1949) 1949
phosphates (1663) 1663
mice (1576) 1576
biochemistry & molecular biology (1547) 1547
sphingosine - metabolism (1315) 1315
research (1287) 1287
cell biology (1205) 1205
sphingosine - pharmacology (1188) 1188
lysophospholipids - metabolism (1100) 1100
lipids (1030) 1030
signal transduction (942) 942
male (916) 916
apoptosis (865) 865
activation (811) 811
female (804) 804
cells, cultured (783) 783
sphingolipids (748) 748
receptors, lysosphingolipid - metabolism (724) 724
fty720 (709) 709
rats (655) 655
inflammation (645) 645
article (640) 640
physiological aspects (635) 635
sphingosine kinase (633) 633
ceramide (630) 630
lysophosphatidic acid (629) 629
lysophospholipids - pharmacology (619) 619
cells (607) 607
expression (583) 583
phosphotransferases - metabolism (582) 582
pharmacology & pharmacy (581) 581
cancer (576) 576
analysis (547) 547
phosphorylation (546) 546
immunology (542) 542
fingolimod hydrochloride (530) 530
protein-coupled receptor (528) 528
mice, inbred c57bl (500) 500
1-phosphate (487) 487
reports (480) 480
lysophospholipids (469) 469
kinases (459) 459
proteins (454) 454
multiple sclerosis (437) 437
receptors (434) 434
endothelial-cells (425) 425
cell line (415) 415
in-vivo (409) 409
universities and colleges (406) 406
s1p (397) 397
signal transduction - drug effects (387) 387
receptor (373) 373
oncology (371) 371
angiogenesis (367) 367
multidisciplinary sciences (362) 362
biophysics (361) 361
metabolism (359) 359
neurosciences (355) 355
migration (352) 352
lymphocyte egress (351) 351
propylene glycols - pharmacology (350) 350
gene expression (348) 348
physiology (340) 340
health aspects (335) 335
research article (335) 335
enzymes (334) 334
cell line, tumor (330) 330
mice, knockout (329) 329
receptors, lysosphingolipid - genetics (327) 327
endothelium (323) 323
molecular-cloning (316) 316
sphingosine 1-phosphate receptor (313) 313
sphingosine 1-phosphate receptors (310) 310
inhibition (307) 307
rodents (306) 306
biochemistry (305) 305
sphingosine - physiology (304) 304
proliferation (303) 303
sphingolipids - metabolism (302) 302
kinase (300) 300
protein-coupled receptors (300) 300
biology (295) 295
signal transduction - physiology (295) 295
disease models, animal (292) 292
phosphotransferases - genetics (291) 291
medicine, research & experimental (280) 280
dose-response relationship, drug (278) 278
medicine (276) 276
enzyme inhibitors - pharmacology (274) 274
hematology (272) 272
immunosuppressive agents - pharmacology (271) 271
calcium - metabolism (268) 268
fingolimod (266) 266
lysophospholipids - physiology (263) 263
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (7685) 7685
Japanese (43) 43
Chinese (18) 18
Korean (11) 11
French (8) 8
German (8) 8
Hungarian (6) 6
Russian (6) 6
Spanish (3) 3
Polish (2) 2
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 2, pp. 751 - 756
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2018, Volume 25, Issue 1, pp. 16 - 26
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2013, Volume 33, Issue 7, pp. 1505 - 1512
OBJECTIVE—Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins. We previously demonstrated that FTY720, a... 
Inflammation | High-density lipoproteins | T cells | Macrophage | Murine models of disease | Sphingosine 1-phosphate | CELLS | ACTIVATION | APOLIPOPROTEIN M | SPHINGOSINE-1-PHOSPHATE ANALOG | macrophage | high-density lipoproteins | DEFICIENT MICE | HYPERLIPIDEMIC MICE | murine models of disease | HIGH-DENSITY-LIPOPROTEIN | REDUCES ATHEROSCLEROSIS | inflammation | IMMUNE-RESPONSES | FTY720 | PERIPHERAL VASCULAR DISEASE | sphingosine 1-phosphate | HEMATOLOGY | Inflammation - pathology | Sulfhydryl Compounds - pharmacology | Atherosclerosis - genetics | Dendritic Cells - immunology | Humans | Aorta - metabolism | Aortic Diseases - metabolism | CD4-Positive T-Lymphocytes - immunology | Inflammation - metabolism | U937 Cells | Lipids - blood | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Dendritic Cells - drug effects | Receptors, Lysosphingolipid - metabolism | Macrophages - immunology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Aortic Diseases - immunology | Aorta - drug effects | Aorta - immunology | Inflammation - immunology | Biomarkers - blood | Atherosclerosis - metabolism | Cardiovascular Agents - pharmacology | Mice, Knockout | Aorta - pathology | Endothelial Cells - immunology | Aortic Diseases - genetics | Animals | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Inflammation - genetics | Receptors, Lysosphingolipid - agonists | Macrophages - drug effects | Inflammation - prevention & control | Lymphopenia - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Macrophage Activation - drug effects | Atherosclerosis - prevention & control | CD4-Positive T-Lymphocytes - drug effects | Endothelial Cells - drug effects
Journal Article
Advances in Biological Regulation, ISSN 2212-4926, 05/2018, Volume 68, pp. 97 - 106
The bioactive lipid, sphingosine 1-phosphate (S1P) is produced by phosphorylation of sphingosine and this is catalysed by two sphingosine kinase isoforms (SK1... 
Sphingosine kinase | Cancer cell-fibroblast interactions | Metastasis | Sphingosine 1-phosphate receptors | Sphingosine 1-phosphate | Phosphates | Enzymes | Protein-protein interactions | Sphingosine | Cancer
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 2015, Volume 21, Issue 6, pp. 354 - 363
Highlights • S1P is a pleiotropic signaling molecule that regulates BBB permeability. • Fingolimod targets S1P receptors and may have therapeutic potential in... 
Pathology | blood–brain barrier | sphingosine 1-phosphate | neuroinflammation | astrocyte | fingolimod | multiple sclerosis | Neuroinflammation | Multiple sclerosis | Astrocyte | Blood-brain barrier | Fingolimod | Sphingosine 1-phosphate | blood-brain barrier | MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | RELAPSING MULTIPLE-SCLEROSIS | ORAL FINGOLIMOD | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASTROCYTE-ENDOTHELIAL INTERACTIONS | PROTEIN-COUPLED RECEPTORS | FINGOLIMOD FTY720 | CELL BIOLOGY | VE-CADHERIN | CENTRAL-NERVOUS-SYSTEM | PLACEBO-CONTROLLED TRIAL | SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 | Fingolimod Hydrochloride - pharmacology | Lysophospholipids - metabolism | Humans | Astrocytes - pathology | Capillary Permeability - drug effects | Lysophospholipids - immunology | Astrocytes - immunology | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Astrocytes - drug effects | Blood-Brain Barrier - immunology | Endothelial Cells - metabolism | Sphingosine - immunology | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Endothelial Cells - immunology | Blood-Brain Barrier - pathology | Receptors, Lysosphingolipid - immunology | Sphingosine - analogs & derivatives | Animals | Signal Transduction - drug effects | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Endothelial Cells - pathology | Immunologic Factors - pharmacology | Astrocytes - metabolism | Endothelial Cells - drug effects | Multiple Sclerosis - drug therapy | Phosphates | Sphingosine | Permeability
Journal Article