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Photochemistry and Photobiology, ISSN 0031-8655, 07/2017, Volume 93, Issue 4, pp. 1016 - 1024
Naproxen possesses anti‐proliferative and pro‐apoptotic effects besides its known anti‐inflammatory functions. Here, we demonstrate the anticancer effects of... 
APOPTOSIS | BIOPHYSICS | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | INDUCED SKIN CARCINOGENESIS | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTANT P53 | ENDOPLASMIC-RETICULUM STRESS | NF-KAPPA-B | CANCER | PHOTOCARCINOGENESIS | PROSTAGLANDIN E-2 | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Neoplasms, Radiation-Induced - etiology | Naproxen - pharmacology | Patched-1 Receptor - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Skin Neoplasms - prevention & control | Ultraviolet Rays | Carcinoma, Basal Cell - etiology | Epithelial-Mesenchymal Transition | Biomarkers, Tumor - metabolism | Carcinoma, Basal Cell - prevention & control | Female | Neoplasms, Radiation-Induced - prevention & control | Antineoplastic Agents - pharmacology | Neoplasms, Radiation-Induced - pathology | Skin Neoplasms - pathology | Mice, Hairless | Mice, Transgenic | Carcinoma, Basal Cell - pathology | Carcinoma, Squamous Cell - prevention & control | Unfolded Protein Response | Neoplasms, Radiation-Induced - metabolism | Carcinoma, Basal Cell - metabolism | Skin Neoplasms - metabolism | Carcinoma, Squamous Cell - etiology | Animals | Cell Line, Tumor | Skin Neoplasms - etiology | Squamous cell carcinoma | Naproxen | Analysis | Skin cancer | Vimentin | Animal models | Mesenchyme | Cyclin D1 | Carcinogenesis | E-cadherin | Anticancer properties | Carcinogens | N-Cadherin | Protein folding | Proliferating cell nuclear antigen | Inhibition | Invasiveness | Inflammation | Hairless | Ablation | Nitric-oxide synthase | Ultraviolet radiation | Skin | Cyclooxygenase-2 | Tumors | Cancer | Apoptosis | Index Medicus | UVB | skin | photocarcinogenesis | inflammation | UPR signaling
Journal Article
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 06/2018, Volume 192, Issue 3, pp. 271 - 283
Head and neck squamous cell carcinoma (HNSCC) is a highly immunosuppressive malignancy. Exosomes in HNSCC patients' plasma are enriched in inhibitory cargo and... 
tumour‐derived exosomes (TEX) | disease progression | T cell‐derived exosomes | HNSCC | immune regulation | tumour-derived exosomes (TEX) | T cell-derived exosomes | HEAD | MELANOMA | REGULATORY T-CELLS | CANCER EXOSOMES | IMMUNOLOGY | EXPRESSION | Exosomes - metabolism | CD8-Positive T-Lymphocytes - cytology | OX40 Ligand - metabolism | CD4-Positive T-Lymphocytes - cytology | Humans | Middle Aged | Squamous Cell Carcinoma of Head and Neck - pathology | Cells, Cultured | CTLA-4 Antigen - metabolism | Male | Lewis X Antigen - metabolism | CD3 Complex - metabolism | B7-H1 Antigen - metabolism | Apoptosis - immunology | Flow Cytometry | Cyclooxygenase 2 - metabolism | Biomarkers, Tumor - metabolism | Adult | Female | Aged | COX-2 inhibitors | Squamous cell carcinoma | Analysis | Immunotherapy | Development and progression | T cells | Tumor proteins | Tumors | Enrichment | Plasma | Flow cytometry | CD8 antigen | Antibodies | Cytotoxicity | Lymphocytes T | Malignancy | Exosomes | Prostaglandin endoperoxide synthase | Proteins | Lymphocytes | Bioindicators | Neck | Head | Immunostimulation | Immunoregulation | CD3 antigen | T cell receptors | Disease control | Patients | Molecular chains | CD4 antigen | Immunosuppression | Ox40L protein | Tumor necrosis factor | Biomarkers | Head and neck cancer | Cancer | Apoptosis | Index Medicus | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0136023 - e0136023
Background Immunotherapy can become a crucial therapeutic option to improve prognosis for lung cancer patients. First clinical trials with therapies targeting... 
CELL LUNG-CANCER | TUMOR-INFILTRATING LYMPHOCYTES | INTERLEUKIN-2 | GEFITINIB | IMPACT | MULTIDISCIPLINARY SCIENCES | ANTIBODY | B7-H1 | T-CELLS | CHEMOTHERAPY | LIGAND 1 EXPRESSION | Adenocarcinoma - pathology | Prognosis | Follow-Up Studies | Lung Neoplasms - mortality | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Carcinoma, Large Cell - mortality | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Carcinoma, Squamous Cell - mortality | Neoplasm Grading | Biomarkers, Tumor - metabolism | Female | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Large Cell - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Carcinoma, Squamous Cell - therapy | Programmed Cell Death 1 Receptor - metabolism | Survival Rate | Combined Modality Therapy | Lung Neoplasms - therapy | Carcinoma, Non-Small-Cell Lung - mortality | B7-H1 Antigen - metabolism | Carcinoma, Non-Small-Cell Lung - therapy | Adenocarcinoma - therapy | Aged | Neoplasm Staging | Carcinoma, Large Cell - therapy | Adenocarcinoma - mortality | Care and treatment | Physiological aspects | Genetic aspects | Research | Lung cancer, Non-small cell | Apoptosis | Immunohistochemistry | Thoracic surgery | PD-1 protein | Lung cancer | Clinical trials | Oncology | Cancer therapies | Lymph nodes | Subgroups | Proteins | Rank tests | Regression models | Bcl-x protein | Lymphocytes | Immunotherapy | Medical research | Immunoglobulins | Squamous cell carcinoma | Cell survival | Cytokines | Hematology | Tumor cells | Breast cancer | Regression analysis | Patients | Medicine | Pathology | Chemotherapy | Hospitals | Cell death | Medical prognosis | PD-L1 protein | Ligands | Diagnostic systems | Solid tumors | Lymph | Cancer | Tumors | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 01/2012, Volume 31, Issue 2, pp. 149 - 160
MicroRNAs are often associated with the pathogenesis of many cancers, including head and neck squamous cell carcinoma (HNSCC). In particular, microRNA-21... 
nanog | Stat-3 | miR-21 | hyaluronan | CD44 | head & neck cancer | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | RHO-KINASE | TUMOR-CELLS | BREAST | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | CANCER STATISTICS | NF-KAPPA-B | PROGRESSION | Promoter Regions, Genetic | Nanog Homeobox Protein | Signal Transduction | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Homeodomain Proteins - metabolism | Humans | Drug Resistance, Neoplasm | MicroRNAs - metabolism | Head and Neck Neoplasms - metabolism | Head and Neck Neoplasms - pathology | Cell Nucleus - metabolism | Hyaluronic Acid - metabolism | Hyaluronan Receptors - metabolism | Cell Line, Tumor | Head and Neck Neoplasms - genetics | MicroRNAs - genetics | STAT3 Transcription Factor - metabolism | Physiological aspects | Head and neck cancer | Genetic aspects | MicroRNA | Research | Stem cells | Signal transduction | Chemotherapy | Head & neck cancer | Gene expression | Drug resistance | Tyrosine | Chromatin | IAP protein | Cell survival | Immunoprecipitation | Tumor cells | Chemoresistance | Stat3 protein | siRNA | Nuclear transport | Promoters | CD44 antigen | Transcription activation | Tumor suppressor genes | miRNA | Apoptosis | Tumors | squamous cell carcinoma | Index Medicus | Nanog
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e103698 - e103698
Journal Article
International Journal of Cancer, ISSN 0020-7136, 11/2018, Volume 143, Issue 10, pp. 2561 - 2574
PD‐1 is highly expressed on tumor‐infiltrated antigen‐specific T cells and limit the antitumor function. Blocking of PD‐1/PD‐L1 signaling has shown... 
esophageal squamous cell carcinoma | TGF‐β | MAGE‐A3 | programmed death receptor 1 |