Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1813) 1813
humans (1790) 1790
src-family kinases - metabolism (1456) 1456
index medicus (1352) 1352
mice (1215) 1215
phosphorylation (1201) 1201
signal transduction (1057) 1057
immunology (1056) 1056
activation (671) 671
cell biology (618) 618
protein-tyrosine kinases - metabolism (554) 554
src-family kinases (529) 529
biochemistry & molecular biology (501) 501
kinases (477) 477
proteins (445) 445
cells, cultured (437) 437
src-family kinases - genetics (433) 433
cell line (430) 430
female (358) 358
research article (357) 357
mice, inbred c57bl (349) 349
multidisciplinary sciences (340) 340
male (333) 333
signal-transduction (333) 333
src-family kinases - antagonists & inhibitors (333) 333
expression (330) 330
oncology (323) 323
tyrosine (323) 323
article (318) 318
enzyme activation (312) 312
cell line, tumor (309) 309
signal transduction - immunology (302) 302
mice, knockout (299) 299
medicine (291) 291
src family kinases (281) 281
src-family kinases - physiology (281) 281
science (273) 273
research (272) 272
tyrosine - metabolism (272) 272
protein-tyrosine kinase (269) 269
cancer (267) 267
tyrosine kinase (264) 264
molecular sequence data (254) 254
apoptosis (250) 250
rats (250) 250
amino acid sequence (249) 249
signal transduction - drug effects (238) 238
syk kinase (238) 238
tyrosine phosphorylation (232) 232
hematology (222) 222
protein binding (220) 220
b-lymphocytes - immunology (217) 217
src (208) 208
gene expression (205) 205
signaling (203) 203
src-family kinases - immunology (203) 203
antigen receptor (201) 201
biology (200) 200
proto-oncogene proteins - metabolism (200) 200
protein-tyrosine kinases - genetics (195) 195
signal transduction - physiology (195) 195
c-src (194) 194
cells (191) 191
t-lymphocytes - immunology (191) 191
lymphocyte activation (184) 184
mutation (184) 184
tumor cells, cultured (184) 184
rodents (180) 180
transfection (180) 180
intracellular signaling peptides and proteins (179) 179
phosphorylation - drug effects (177) 177
receptor (172) 172
pyrimidines - pharmacology (171) 171
physiological aspects (169) 169
blotting, western (167) 167
src protein (167) 167
analysis (161) 161
enzyme inhibitors - pharmacology (159) 159
protein (156) 156
biochemistry (155) 155
focal adhesion kinase (155) 155
cell proliferation (153) 153
protein kinase inhibitors - pharmacology (152) 152
protein-tyrosine kinases - physiology (151) 151
medicine, research & experimental (150) 150
cell adhesion & migration (149) 149
inflammation (149) 149
phosphatidylinositol 3-kinases - metabolism (148) 148
cell adhesion (146) 146
nf-kappa-b (146) 146
t-cells (146) 146
lymphocyte specific protein tyrosine kinase p56 (145) 145
phosphotransferases (145) 145
in-vivo (143) 143
phosphoproteins - metabolism (137) 137
receptors, antigen, b-cell - metabolism (136) 136
calcium - metabolism (135) 135
inhibition (134) 134
abridged index medicus (133) 133
lymphocytes (133) 133
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text B cell-specific loss of lyn kinase leads to autoimmunity
by Lamagna, Chrystelle and Hu, Yongmei and DeFranco, Anthony L and Lowell, Clifford A
Journal of Immunology, ISSN 0022-1767, 02/2014, Volume 192, Issue 3, pp. 919 - 928
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells: loss of Lyn results in a lupus-like autoimmune disease with hyperactive B cells... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | PROTEIN | DENDRITIC CELLS | DISEASE | GERMINAL CENTER | DEFICIENT MICE | IMMUNOLOGY | MATURATION | AUTOANTIBODY PRODUCTION | T-CELLS | T-Lymphocyte Subsets - immunology | Antibody Specificity | Antibodies, Antinuclear - biosynthesis | Myeloproliferative Disorders - enzymology | Immune Complex Diseases - immunology | Spleen - immunology | Kidney - pathology | Antibodies, Antinuclear - immunology | Cell Count | Germinal Center - immunology | Kidney - immunology | Homeostasis | Myeloproliferative Disorders - immunology | Immunoglobulin M - immunology | Myeloproliferative Disorders - genetics | src-Family Kinases - deficiency | Lupus Nephritis - etiology | Immunoglobulin G - biosynthesis | Autoimmunity - immunology | Immunoglobulin G - immunology | Myeloid Differentiation Factor 88 - immunology | Calcium Signaling - immunology | Spleen - pathology | Immunoglobulin Class Switching | Disease Models, Animal | B-Lymphocytes - enzymology | Lymphocyte Activation | Mice, Inbred C57BL | Mice, Transgenic | Lupus Nephritis - immunology | Germinal Center - pathology | Organ Specificity | src-Family Kinases - immunology | Immune Complex Diseases - pathology | Antibodies, Antinuclear - genetics | Lupus Nephritis - enzymology | Animals | B-Lymphocytes - immunology | Myeloid Differentiation Factor 88 - deficiency | Lymphopoiesis - immunology | Mice | src-Family Kinases - genetics | Immunoglobulin M - biosynthesis | Plasma Cells - immunology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
by Liu, Haibo and Jin, Jing and Cao, Xuetao and Xu, Sheng and Han, Chaofeng and Li, Nan
Nature Immunology, ISSN 1529-2908, 08/2010, Volume 11, Issue 8, pp. 734 - 742
Integrins are critical for the migration and function of leukocytes in inflammation. However, the interaction between integrin alpha(M) (CD11b), which has high... 
CROSS-REGULATION | DENDRITIC CELLS | MEDIATOR | DISEASE | ADAPTERS | IMMUNOLOGY | DIFFERENTIATE | Proto-Oncogene Proteins c-cbl - metabolism | Protein-Tyrosine Kinases - metabolism | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Protein-Tyrosine Kinases - immunology | Myeloid Differentiation Factor 88 - immunology | Adaptor Proteins, Signal Transducing - immunology | Syk Kinase | Macrophages - immunology | CD11b Antigen - immunology | Signal Transduction | Toll-Like Receptors - immunology | Escherichia coli - immunology | Inflammation - immunology | Adaptor Proteins, Vesicular Transport - immunology | src-Family Kinases - immunology | Mice, Knockout | Gene Expression Regulation, Enzymologic | Immunity, Innate - immunology | Animals | Escherichia coli Infections - immunology | Mice | Enzyme Activation | Adaptor Proteins, Signal Transducing - metabolism | Inflammation - enzymology | Myeloid Differentiation Factor 88 - metabolism | Proto-Oncogene Proteins c-cbl - immunology | Cell receptors | Immune response | Cell adhesion | Physiological aspects | Research | Health aspects | Integrins
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via FcγRIIIB and Mac-1
by Behnen, Martina and Leschczyk, Christoph and Möller, Sonja and Batel, Tobit and Klinger, Matthias and Solbach, Werner and Laskay, Tamás
Journal of Immunology, ISSN 0022-1767, 08/2014, Volume 193, Issue 4, pp. 1954 - 1965
Canonical neutrophil antimicrobial effector mechanisms, such as degranulation, production of reactive oxygen species, and release of neutrophil extracellular... 
MAMMALIAN TARGET | NADPH OXIDASE | NETTING NEUTROPHILS | SIGNALING PATHWAYS | RESPIRATORY BURST | SYNOVIAL-FLUID | SUPEROXIDE-PRODUCTION | IN-VIVO | IMMUNOLOGY | RECEPTOR-III | CELL-DEATH | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - immunology | Macrophage-1 Antigen - immunology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Receptors, IgG - antagonists & inhibitors | Protein-Tyrosine Kinases - immunology | Lymphocyte Function-Associated Antigen-1 - immunology | Macrophage-1 Antigen - metabolism | Syk Kinase | CD11a Antigen - metabolism | Butadienes - pharmacology | Neutrophil Activation - immunology | GPI-Linked Proteins - immunology | Cell Degranulation | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | src-Family Kinases - antagonists & inhibitors | Autoimmune Diseases - immunology | Cells, Cultured | Neutrophils - immunology | Imidazoles - pharmacology | Inflammation - immunology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Pyrimidines - pharmacology | Receptors, IgG - immunology | src-Family Kinases - immunology | CD18 Antigens - metabolism | Mesalamine - pharmacology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Aminopyrine - pharmacology | Ascorbic Acid - pharmacology | Pyridines - pharmacology | Antigen-Antibody Complex - immunology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The ins and outs of leukocyte integrin signaling
by Abram, Clare L and Lowell, Clifford A
Annual Review of Immunology, ISSN 0732-0582, 2009, Volume 27, Issue 1, pp. 339 - 362
Integrins are the principal cell adhesion receptors that mediate leukocyte migration and activation in the immune system. These receptors signal... 
Rap GTPase | Kinases | Inside-out | ITAM | Outside-in | HUMAN NEUTROPHILS | BETA-3-INTEGRIN-DEFICIENT MICE | TYROSINE PHOSPHORYLATION | WISKOTT-ALDRICH-SYNDROME | PLATELET-FUNCTION | BETA-1-INTEGRIN FUNCTION | BETA CYTOPLASMIC DOMAIN | IMMUNOLOGY | SRC-FAMILY KINASES | kinases | T-CELL-ACTIVATION | inside-out | BINDING-LIKE DOMAIN | outside-in | Protein Kinases - metabolism | rap GTP-Binding Proteins - immunology | Amino Acid Sequence | Signal Transduction | Cytoskeleton - immunology | Endothelial Cells - metabolism | Humans | Integrins - immunology | Extracellular Matrix - immunology | Integrins - chemistry | Extracellular Matrix - metabolism | Integrins - genetics | Molecular Sequence Data | Integrins - metabolism | Endothelial Cells - immunology | Leukocytes - immunology | Animals | Protein Kinases - immunology | Cytoskeleton - metabolism | Mice | rap GTP-Binding Proteins - metabolism | Leukocytes - metabolism | Cell Movement | Physiological aspects | Properties | Integrins | Immune system | Immunological research
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation
by Jabara, Haifa H and McDonald, Douglas R and Janssen, Erin and Massaad, Michel J and Ramesh, Narayanaswamy and Borzutzky, Arturo and Rauter, Ingrid and Benson, Halli and Schneider, Lynda and Baxi, Sachin and Recher, Mike and Notarangelo, Luigi D and Wakim, Rima and Dbaibo, Ghassan and Dasouki, Majed and Al-Herz, Waleed and Barlan, Isil and Baris, Safa and Kutukculer, Necil and Ochs, Hans D and Plebani, Alessandro and Kanariou, Maria and Lefranc, Gerard and Reisli, Ismail and Fitzgerald, Katherine A and Golenbock, Douglas and Manis, John and Keles, Sevgi and Ceja, Reuben and Chatila, Talal A and Geha, Raif S
Nature Immunology, ISSN 1529-2908, 06/2012, Volume 13, Issue 6, pp. 612 - 620
The adaptors DOCK8 and MyD88 have been linked to serological memory. Here we report that DOCK8-deficient patients had impaired antibody responses and... 
STAT3 ACTIVATION | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | HUMORAL IMMUNITY | INDUCTION | IMMUNOLOGY | ANTIBODY-RESPONSES | NF-KAPPA-B | SYK TYROSINE KINASE | CPG ODN | MYD88 | Phosphorylation | Lymphocyte Activation | Humans | Mice, Inbred C57BL | Neutrophils - immunology | Child, Preschool | src-Family Kinases - immunology | Mice, Knockout | Toll-Like Receptor 9 - immunology | Cell Differentiation - immunology | Animals | B-Lymphocytes - immunology | Flow Cytometry | Adolescent | Myeloid Differentiation Factor 88 - immunology | Guanine Nucleotide Exchange Factors - immunology | Mice | Mice, Inbred BALB C | STAT3 Transcription Factor - immunology | Child | Immunologic Memory - immunology | Focal Adhesion Kinase 2 - immunology | Physiological aspects | Toll-like receptors | Cellular signal transduction | B cells | Research
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text The Strength of T Cell Receptor Signal Controls the Polarization of Cytotoxic Machinery to the Immunological Synapse
by Jenkins, Misty R and Tsun, Andy and Stinchcombe, Jane C and Griffiths, Gillian M
Immunity, ISSN 1074-7613, 10/2009, Volume 31, Issue 4, pp. 621 - 631
Killing by cytotoxic T lymphocytes (CTLs) is mediated by the secretion of lytic granules. The centrosome plays a key role in granule delivery, polarizing to... 
MOLIMMUNO | CELLIMMUNO | ACTIVATION | TCR | POSITIVE SELECTION | CYTOSKELETON | PHOSPHORYLATION | MICROTUBULE-ORGANIZING CENTER | CTL | IMMUNOLOGY | ANTIGEN RECEPTOR | ALTERED PEPTIDE LIGANDS | SECRETORY LYSOSOMES | Ovalbumin - immunology | Extracellular Signal-Regulated MAP Kinases - metabolism | Immunological Synapses - metabolism | Extracellular Signal-Regulated MAP Kinases - immunology | Centrosome - ultrastructure | Signal Transduction - immunology | Cytoplasmic Granules - metabolism | Peptide Fragments - immunology | src-Family Kinases - metabolism | Female | Receptors, Antigen, T-Cell - immunology | Phosphorylation - immunology | T-Lymphocytes, Cytotoxic - immunology | Cell Polarity - immunology | Microscopy, Electron, Transmission | Immunological Synapses - ultrastructure | Centrosome - immunology | Receptors, Antigen, T-Cell - metabolism | Mice, Inbred C57BL | Cell Degranulation - immunology | src-Family Kinases - immunology | Centrosome - metabolism | Animals | Cytoplasmic Granules - ultrastructure | T-Lymphocytes, Cytotoxic - metabolism | Immunological Synapses - immunology | Mice | Cytotoxicity, Immunologic - immunology | Cytoplasmic Granules - immunology | T-Lymphocytes, Cytotoxic - ultrastructure | T cells | Machinery | Magneto-electric machines | Scholarships & fellowships | Statistical analysis | Peptides | Cytokines | Microscopy | Cytotoxicity | Ligands | T cell receptors | Kinases | Variance analysis | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Tyrosine kinases and inflammatory signalling
by Page, Theresa H and Smolinska, Maria and Gillespie, Justin and Urbaniak, Anna M and Foxwell, Brian M.J
Current Molecular Medicine, ISSN 1566-5240, 2009, Volume 9, Issue 1, pp. 69 - 85
The activity of tyrosine kinases is central to many cellular processes, and accumulating evidence suggests that their role in inflammation is no less profound.... 
Tyrosine kinases | Inflammation | Cytokines | Rheumatoid Arthritis | Macrophages | MEDICINE, RESEARCH & EXPERIMENTAL | COLLAGEN-INDUCED ARTHRITIS | X-LINKED AGAMMAGLOBULINEMIA | INNATE IMMUNE-RESPONSE | SRC-FAMILY KINASES | TNF-ALPHA PRODUCTION | RECEPTOR-MEDIATED PHAGOCYTOSIS | macrophages | TUMOR-NECROSIS-FACTOR | AFFINITY IGE RECEPTOR | cytokines | NF-KAPPA-B | PATTERN-RECOGNITION RECEPTORS | Protein-Tyrosine Kinases - metabolism | Humans | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Janus Kinases - metabolism | Proto-Oncogene Proteins c-hck - immunology | Protein-Tyrosine Kinases - immunology | Cell Movement - immunology | Signal Transduction - immunology | Focal Adhesion Kinase 2 - metabolism | Adjuvants, Immunologic - metabolism | Gene Expression - immunology | Protein-Tyrosine Kinases - chemistry | src-Family Kinases - metabolism | Janus Kinases - immunology | Antigen-Antibody Complex - metabolism | Toll-Like Receptors - metabolism | Syk Kinase | Cytokines - immunology | Janus Kinases - chemistry | Cytokines - metabolism | Toll-Like Receptors - immunology | Proto-Oncogene Proteins c-hck - metabolism | Inflammation - immunology | src-Family Kinases - immunology | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Focal Adhesion Kinase 2 - chemistry | Mice | Antigen-Antibody Complex - immunology | src-Family Kinases - chemistry | Chronic Disease | Cytokines - biosynthesis | Focal Adhesion Kinase 2 - immunology
Journal Article
Details down arrow
8. Full Text Basophils and the T helper 2 environment can promote the development of lupus nephritis
by Charles, Nicolas and Hardwick, Donna and Daugas, Eric and Illei, Gabor G and Rivera, Juan
Nature Medicine, ISSN 1078-8956, 06/2010, Volume 16, Issue 6, pp. 701 - 707
In systemic lupus erythematosus (SLE), self-reactive antibodies can target the kidney (lupus nephritis), leading to functional failure and possible mortality.... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAST-CELLS | RENAL-DISEASE | CELL BIOLOGY | MRL-LPR MICE | REVISED CRITERIA | INTERFERON-GAMMA | MURINE LUPUS | AUTOIMMUNE-DISEASE | T-CELLS | LYN-DEFICIENT MICE | IMMUNOGLOBULIN-E | Spleen - immunology | Humans | Lupus Nephritis - immunology | Th2 Cells - immunology | Lymph Nodes - immunology | src-Family Kinases - immunology | Lupus Nephritis - etiology | Interleukin-4 - immunology | Autoantibodies - immunology | L-Selectin - immunology | Animals | Histocompatibility Antigens Class II - immunology | Immunoglobulin E - immunology | Basophils - immunology | Lupus Erythematosus, Systemic - immunology | HLA-DR Antigens - immunology | Mice | Complications and side effects | Nephritis | Systemic lupus erythematosus | Autoantibodies | Physiological aspects | Research | T cells | Health aspects | Risk factors | Lupus | Immunology | Kidney diseases | Kinases | Rodents
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Distinct Roles for Neutrophils and Dendritic Cells in Inflammation and Autoimmunity in motheaten Mice
by Abram, Clare L and Roberge, Gray L and Pao, Lily I and Neel, Benjamin G and Lowell, Clifford A
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 489 - 501
The mouse has long served as a paradigm for complex autoimmune and inflammatory disease. Null mutations in which encodes the nonreceptor protein-tyrosine... 
SIGNAL-TRANSDUCTION | VIABLE MOTHEATEN | MACROPHAGES | KINASE | DISEASE | IMMUNOLOGY | SHP-1 | PROTEIN-TYROSINE-PHOSPHATASE | SYSTEMIC AUTOIMMUNITY | T-CELLS | DEFICIENCY | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - immunology | Calgranulin A - metabolism | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Humans | Autoimmunity - genetics | Immunoblotting | Intracellular Signaling Peptides and Proteins - immunology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Calgranulin A - genetics | Mice, 129 Strain | CD11c Antigen - immunology | Protein-Tyrosine Kinases - immunology | CD11c Antigen - metabolism | Inflammation - metabolism | CD11c Antigen - genetics | Flow Cytometry | Autoimmunity - immunology | Myeloid Differentiation Factor 88 - immunology | src-Family Kinases - metabolism | Female | Calgranulin A - immunology | Neutrophils - metabolism | Syk Kinase | Dendritic Cells - metabolism | Dermis - metabolism | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Neutrophils - immunology | Mice, Transgenic | Inflammation - immunology | src-Family Kinases - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Dermis - immunology | Mice, Knockout | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Cell Line, Tumor | Inflammation - genetics | Dermis - pathology | Mice | Mutation | Myeloid Differentiation Factor 88 - metabolism | Autoimmunity | Dendritic cells | Analysis | Skin diseases | Inflammation | Phosphotransferases | Integrins
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation
by Volmering, Stephanie and Block, Helena and Boras, Mark and Lowell, Clifford A and Zarbock, Alexander
Immunity, ISSN 1074-7613, 01/2016, Volume 44, Issue 1, pp. 73 - 87
Neutrophils are recruited from the blood to sites of sterile inflammation, where they are involved in wound healing but can also cause tissue damage. During... 
phospholipase C | signaling | Btk | Src family kinases | integrin | fMLF | WASp | FMLF | Signaling | Integrin | Phospholipase C | MIGRATION | PATHWAYS | RECRUITMENT | RESPONSES | HCK | BRUTONS TYROSINE KINASE | DEFICIENT | TRANSDUCTION | IMMUNOLOGY | SRC-FAMILY KINASES | SH3 DOMAIN | Liver Diseases - immunology | Protein-Tyrosine Kinases - metabolism | Integrins - immunology | Inflammation | Integrins - metabolism | Protein-Tyrosine Kinases - immunology | Necrosis - immunology | Microscopy, Confocal | Signal Transduction - immunology | Animals | Flow Cytometry | Mice | Liver Diseases - metabolism | N-Formylmethionine Leucyl-Phenylalanine - immunology | Neutrophil Infiltration - immunology | Peptides | Integrins | Tyrosine | Analgesics | Phospholipases | Wasps | Flow cytometry | Phosphorylation | Cloning | Neutrophils | Kinases | Experiments | Recruitment | Proteins | Rodents | Gangrene | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases
by Nishi, Hiroshi and Furuhashi, Kazuhiro and Cullere, Xavier and Saggu, Gurpanna and Miller, Mark J and Chen, Yunfeng and Rosetti, Florencia and Hamilton, Samantha L and Yang, Lihua and Pittman, Spencer P and Liao, Jiexi and Herter, Jan M and Berry, Jeffrey C and DeAngelo, Daniel J and Zhu, Cheng and Tsokos, George C and Mayadas, Tanya N
Journal of Clinical Investigation, ISSN 0021-9738, 10/2017, Volume 127, Issue 10, pp. 3810 - 3826
The kidney glomerular capillaries are frequent sites of immune complex deposition and subsequent neutrophil accumulation in post-infectious and rapidly... 
IMMUNE-COMPLEXES | MEDICINE, RESEARCH & EXPERIMENTAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | RESPIRATORY BURST | ABL FAMILY KINASES | IN-VIVO | ANTIENDOTHELIAL CELL ANTIBODIES | LEUKOCYTE ADHESION | SALT-INDUCIBLE KINASES | APPROVED DRUGS | IMAGING REVEALS | Capillaries - pathology | Nitriles - pharmacology | Proto-Oncogene Proteins c-abl - antagonists & inhibitors | Humans | Quinolines - pharmacology | Receptors, IgG - genetics | Immunoglobulin G - immunology | Proto-Oncogene Proteins c-abl - immunology | Neutrophils - pathology | Proto-Oncogene Proteins c-abl - genetics | Aniline Compounds - pharmacology | src-Family Kinases - antagonists & inhibitors | Glomerulonephritis - genetics | Neutrophils - immunology | Glomerulonephritis - immunology | Kidney Glomerulus - pathology | Receptors, IgG - immunology | src-Family Kinases - immunology | Mice, Knockout | Animals | Glomerulonephritis - pathology | HL-60 Cells | Capillaries - immunology | Mice | Kidney Glomerulus - immunology | Tyrosine | Lupus | Glomerulonephritis | Nephritis | Immunoglobulins | Kidneys | Syngeneic grafts | Leukemia | Immunoglobulin G | Neutrophils | Polymerization | Arthritis | Leukocytes (neutrophilic) | Inflammation | Fc receptors | Microscopy | Actin | Rodents | Ligands | Physiology | Capillaries | Protein-tyrosine kinase | Kidney transplantation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
by Abram, Clare L and Jakus, Zoltán and Hu, Yongmei and Lowell, Clifford A and Mócsai, Attila and Lanier, Lewis L
Nature Immunology, ISSN 1529-2908, 12/2006, Volume 7, Issue 12, pp. 1326 - 1333
At sites of inflammation, ligation of leukocyte integrins is critical for the activation of cellular effector functions required for host defense. However, the... 
ADHESION | ALPHA(IIB)BETA | RESPIRATORY BURST | SYK | RECEPTOR | DEGRANULATION | MICE | BETA-CYTOPLASMIC DOMAINS | IMMUNOLOGY | PROTEINS | SRC-FAMILY KINASES | Phosphorylation | Protein-Tyrosine Kinases - metabolism | Integrins - immunology | Neutrophils - immunology | Immunoblotting | Integrins - metabolism | Protein-Tyrosine Kinases - immunology | Mice, Knockout | Signal Transduction - immunology | Macrophages - metabolism | Tyrosine - metabolism | Animals | Flow Cytometry | Amino Acid Motifs - immunology | Adaptor Proteins, Signal Transducing - immunology | Mice | Receptors, Immunologic - immunology | Adaptor Proteins, Signal Transducing - metabolism | Neutrophils - metabolism | Macrophages - immunology | Receptors, Immunologic - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights