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Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9678, pp. 1905 - 1917
Summary Glucocorticoid resistance or insensitivity is a major barrier to the treatment of several common inflammatory diseases—including chronic obstructive... 
Internal Medicine | RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | OBSTRUCTIVE PULMONARY-DISEASE | HISTONE DEACETYLASE ACTIVITY | MIGRATION INHIBITORY FACTOR | ULCERATIVE-COLITIS | REGULATORY T-CELLS | RECEPTOR-BETA | RELATIVE CORTICOSTEROID INSENSITIVITY | BLOOD MONONUCLEAR-CELLS | RESPIRATORY-DISTRESS-SYNDROME | Transcription Factor AP-1 - drug effects | Glucocorticoids - therapeutic use | Transcriptional Activation - genetics | Transcription Factor AP-1 - genetics | Humans | Macrophage Migration-Inhibitory Factors - immunology | Transcriptional Activation - drug effects | Transcription Factor AP-1 - immunology | Histone Deacetylases - immunology | Transcriptional Activation - immunology | ATP-Binding Cassette, Sub-Family B, Member 1 - drug effects | Calcineurin Inhibitors | Macrophage Migration-Inhibitory Factors - genetics | Inflammation - drug therapy | Phosphodiesterase 4 Inhibitors | Anti-Inflammatory Agents - therapeutic use | Mitogen-Activated Protein Kinases - immunology | Genetic Predisposition to Disease - genetics | NF-kappa B - antagonists & inhibitors | Histone Deacetylases - genetics | Macrophage Migration-Inhibitory Factors - drug effects | Repressor Proteins - genetics | Histone Deacetylase 2 | Drug Resistance - drug effects | Inflammation - immunology | Asthma - drug therapy | ATP-Binding Cassette, Sub-Family B, Member 1 - immunology | Drug Resistance - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Drug Resistance - immunology | Repressor Proteins - immunology | Histone Deacetylases - drug effects | Mitogen-Activated Protein Kinases - genetics | Repressor Proteins - drug effects | Mitogen-Activated Protein Kinases - drug effects | Pulmonary Disease, Chronic Obstructive - drug therapy | Corticosteroids | Dosage and administration | Inflammation | Research | Drug resistance | Drug therapy | Health aspects | Complications and side effects | Risk factors | Inflammatory bowel disease | Proteins | Respiratory distress syndrome | Asthma | Steroids
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 2, pp. 324 - 333.e5
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2006, Volume 580, Issue 12, pp. 2903 - 2909
One of the major problems in chemotherapy is multidrug resistance (MDR) against anticancer drugs. ATP-binding cassette (ABC) transporters are a family of... 
Multidrug resistance inhibitors | ATP-binding cassette transporters | Cancer chemotherapy | Multidrug resistance | multidrug resistance | ABC | ABC transporter in placenta | steroid and xenobiotic receptor | MVP | glucosylceramide | glutathione | MDR related protein | MRP | LRP | CMOAT | CYP3A4 | SXR | N-acetylcysteine | Cytochrome p450 3A4 | canalicular multi-organic anion transporter | human embryonic kidney | reactive oxygen species | MDR | GSH | BSO | BCRP | MRP1 | P-gp | transmembrane domains | breast cancer resistance protein | major vault protein | adenosinetriphosphate | TMD | glucosylceramide synthase | HEK | P-glycoprotein | lung resistance-related protein | NAC | dl-buthionine (S,R)-sulfoximine | multidrug resistance protein | GCS | ABC-P | ROS | ATP-binding cassette | ATP | multidrug resistance inhibitors | TRANSPORTER | MEDIATED MULTIDRUG-RESISTANCE | GLUCOSYLCERAMIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | ADRIAMYCIN RESISTANCE | P-GLYCOPROTEIN | CELL BIOLOGY | BIOPHYSICS | METABOLISM | cancer chemotherapy | CERAMIDE GLYCOSYLATION | MODULATOR | CELL-LINE | ATP-Binding Cassette Transporters - chemistry | Drug Resistance, Multiple | Humans | Drug Resistance, Neoplasm | Structure-Activity Relationship | Neoplasms - pathology | ATP-Binding Cassette Transporters - physiology | Neoplasms - drug therapy | Proteins | Drug resistance in microorganisms | Chemotherapy | Analysis | Cytochrome P-450 | Acetylcysteine | Drug therapy | Cancer | Glutathione
Journal Article