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Biochemical Pharmacology, ISSN 0006-2952, 2008, Volume 75, Issue 2, pp. 484 - 493
Aldo-keto reductase (AKR) 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase) regulates ligand access to steroid hormone and prostaglandin... 
Prostaglandin metabolism | Inhibitor design | Steroid hormone metabolism | Cancer treatment | NSAIDs | Chemoprevention | cancer treatment | ANDROGEN RECEPTOR | SIGNALING PATHWAYS | INCREASED EXPRESSION | CRYSTAL-STRUCTURE | prostaglandin metabolism | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PROLIFERATOR-ACTIVATED RECEPTOR | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | chemoprevention | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ACID-BINDING PROTEIN | CYCLOOXYGENASE-2 INHIBITORS | inhibitor design | PHARMACOLOGY & PHARMACY | steroid hormone metabolism | Indomethacin - analogs & derivatives | Oxidation-Reduction | Humans | Enzyme Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Melatonin - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | 3-Hydroxysteroid Dehydrogenases - metabolism | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Catalysis | Neoplasms, Hormone-Dependent - drug therapy | Melatonin - pharmacology | Phenanthrenes - metabolism | Dihydrotestosterone - metabolism | Enzymes | Care and treatment | Synthetic prostaglandins F | Crystals | Hormones | Organic acids | Heterocyclic compounds | Physiological aspects | Glycols | Hormones, Sex | Indomethacin | Structure | Cancer
Journal Article
Journal Article
Science of the Total Environment, ISSN 0048-9697, 04/2018, Volume 619-620, pp. 1482 - 1492
Ill-defined, multi-component mixtures of steroidal pharmaceuticals are present in the aquatic environment. Fish are extremely sensitive to some of these... 
Steroidal pharmaceuticals | Environmental risk assessment | Reproduction | Independent action | Mixture toxicity | Concentration addition | Corticosteroids | Egg industry | Analysis | Estrogen
Journal Article
Journal Article
Journal Article
Journal Article
Prostaglandins and Other Lipid Mediators, ISSN 1098-8823, 01/2016, Volume 122, pp. 18 - 27
Prostacyclin (PGI ) is a key mediator involved in cardiovascular homeostasis, acting predominantly on two receptor types; cell surface IP receptor and... 
pulmonary artery hypertension | PGI2 | prostacyclin | thyroid hormone α receptor | NSAID | triiodothyronine | peroxisome proliferator activated receptor | MLS000389544 | non-steroidal anti-inflammatory drug | thyroid hormone β receptor | TRα | Mesenteric artery | PPAR | MLS | TRβ | PAH | Thyroid hormone | PPARβ/δ | Beraprost | Prostacyclin | Triiodothyronine | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | RATS | IDENTIFICATION | VASCULAR SMOOTH-MUSCLE | CELL BIOLOGY | PROSTANOID RECEPTORS | VESSELS | MICE | NONGENOMIC ACTIONS | AGONIST | Thiazoles - metabolism | Epoprostenol - metabolism | Mesenteric Arteries - physiology | Myography - methods | Rats, Wistar | Thyroid Hormone Receptors beta - chemistry | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Male | Mesenteric Arteries - drug effects | Receptors, Thyroid Hormone - antagonists & inhibitors | Dose-Response Relationship, Drug | Thyroid Hormone Receptors alpha - chemistry | Triiodothyronine - metabolism | Computer Simulation | Protein Domains | Epoprostenol - pharmacology | Triiodothyronine - pharmacology | Thyroid Hormone Receptors beta - metabolism | Models, Molecular | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Binding, Competitive - drug effects | Receptors, Thyroid Hormone - metabolism | Epoprostenol - analogs & derivatives | Animals | Receptors, Thyroid Hormone - chemistry | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Epoprostenol - chemistry | Ligands | Thiazoles - chemistry | Thyroid Hormone Receptors alpha - metabolism | Thiazoles - pharmacology | Vasodilation - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Antiandrogens | Models | Thyroid hormones | Analysis
Journal Article
Journal Article