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1. Full Text Anatomy and Histology of Rodent and Human Major Salivary Glands-Overview of the Japan Salivary Gland Society-Sponsored Workshop
by Amano, Osamu and Mizobe, Kenichi and Bando, Yasuhiko and Sakiyama, Koji
ACTA HISTOCHEMICA ET CYTOCHEMICA, ISSN 0044-5991, 2012, Volume 45, Issue 5, pp. 241 - 250
Major salivary glands of both humans and rodents consist of three pairs of macroscopic glands: parotid, submandibular, and sublingual. These glands secrete... 
mouse | salivary glands | immunohistochemistry | rat | human | Human | Immunohistochemistry | Mouse | Rat | Salivary glands | CELLS | LOCALIZATION | BDNF | IMMOBILIZATION STRESS | RECEPTOR | MAIN EXCRETORY DUCT | CELL BIOLOGY | RAT SUBMANDIBULAR-GLAND | GRANULAR CONVOLUTED TUBULE | EPIDERMAL-GROWTH-FACTOR | EXPRESSION | Special Issue | Histochemistry of Salivary Glands
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2. Full Text Desmoplastic small round cell tumor of the submandibular gland—a rare but distinctive primary salivary gland neoplasm
by Yin, Wei-Hua, MD and Guo, Shuang-Ping, MD and Yang, Hong-Yu, MD and Chan, John K.C., MBBS
Human Pathology, ISSN 0046-8177, 2010, Volume 41, Issue 3, pp. 438 - 442
Summary Desmoplastic small round cell tumor is a highly aggressive neoplasm that generally involves the peritoneum and pelvis of young patients. Only rare... 
Pathology | Salivary gland tumor | Desmoplastic small round cell tumor | Molecular analysis | EWS/WT1 gene fusion | SPECTRUM | PATHOLOGY | Immunohistochemistry | Submandibular Gland Neoplasms - therapy | Submandibular Gland Neoplasms - pathology | Cell Proliferation | Humans | Tumor Suppressor Protein p53 - metabolism | Sarcoma, Small Cell - therapy | In Situ Hybridization, Fluorescence | Male | Treatment Outcome | Combined Modality Therapy | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Sarcoma, Small Cell - metabolism | Submandibular Gland Neoplasms - metabolism | Young Adult | Disease-Free Survival | Keratins - metabolism | Desmin - metabolism | Sarcoma, Small Cell - pathology | Keratin | Analysis | Cancer | Index Medicus
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3. Full Text Head and Neck Salivary Gland Carcinomas—Elective Neck Dissection, Yes or No?
by Nobis, Christopher-Philipp, Cand.Med and Rohleder, Nils H., MD, DDS and Wolff, Klaus-Dietrich, MD, DDS, PhD and Wagenpfeil, Stefan, MSc, PhD and Scherer, Elias Q., MD, PhD and Kesting, Marco R., MD, DDS, PhD
Journal of Oral and Maxillofacial Surgery, ISSN 0278-2391, 2014, Volume 72, Issue 1, pp. 205 - 210
Purpose Surgical resection and subsequent neck dissection (ND) in cases of clinically positive lymph nodes is an accepted primary treatment strategy for... 
Surgery | MANAGEMENT | DENTISTRY, ORAL SURGERY & MEDICINE | DENMARK 1990-2005 | DANISH HEAD | PRIMARY PAROTID CARCINOMA | MUCOEPIDERMOID CARCINOMA | TUMORS | CANCER GROUP DAHANCA | CHEMOTHERAPY | Lymphatic Metastasis - diagnosis | Lymph Nodes - pathology | Follow-Up Studies | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Male | Young Adult | Submandibular Gland Neoplasms - surgery | Neoplasm Grading | Salivary Glands, Minor - surgery | Aged, 80 and over | Adult | Carcinoma, Adenoid Cystic - secondary | Female | Parotid Neoplasms - surgery | Elective Surgical Procedures - methods | Retrospective Studies | Carcinoma - pathology | Radiotherapy, Adjuvant | Child | Carcinoma - secondary | Carcinoma, Adenoid Cystic - surgery | Carcinoma, Mucoepidermoid - secondary | Carcinoma - surgery | Carcinoma, Mucoepidermoid - surgery | Neck Dissection - methods | Adenocarcinoma - secondary | Adolescent | Aged | Neoplasm Staging | Adenocarcinoma - surgery | Cohort Studies | Salivary Gland Neoplasms - surgery | Sects | College teachers | Cancer | Medical informatics | Index Medicus | Abridged Index Medicus | Dentistry
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4. Full Text Salivary Gland Function 5 Years After Radioactive Iodine Ablation in Patients with Differentiated Thyroid Cancer: Direct Comparison of Pre- and Postablation Scintigraphies and Their Relation to Xerostomia Symptoms
by Jeong, Shin Young and Kim, Hae Won and Lee, Sang-Woo and Ahn, Byeong-Cheol and Lee, Jaetae
Thyroid, ISSN 1050-7256, 05/2013, Volume 23, Issue 5, pp. 69 - 616
Background: Chronic sialadenitis is one of the most frequent chronic complications after radioactive iodine (RAI) therapy for thyroid cancer. To evaluate the... 
Thyroid Radiology and Nuclear Medicine | QUANTITATIVE-EVALUATION | RADIOIODINE THERAPY | ENDOCRINOLOGY & METABOLISM | SJOGRENS-SYNDROME | FLOW-RATES | DYSFUNCTION | CARCINOMA | Sialadenitis - diagnostic imaging | Prevalence | Follow-Up Studies | Xerostomia - physiopathology | Submandibular Gland Diseases - epidemiology | Humans | Middle Aged | Submandibular Gland Diseases - diagnostic imaging | Submandibular Gland - secretion | Male | Iodine Radioisotopes - adverse effects | Salivary Glands - diagnostic imaging | Young Adult | Iodine Radioisotopes - therapeutic use | Submandibular Gland - diagnostic imaging | Salivary Glands - radiation effects | Adult | Female | Sialadenitis - etiology | Republic of Korea - epidemiology | Xerostomia - epidemiology | Sialadenitis - physiopathology | Severity of Illness Index | Thyroid Neoplasms - surgery | Sialadenitis - epidemiology | Salivary Glands - secretion | Thyroid Neoplasms - radiotherapy | Combined Modality Therapy - adverse effects | Thyroidectomy | Radiopharmaceuticals - administration & dosage | Submandibular Gland - radiation effects | Thyroid Neoplasms - physiopathology | Iodine Radioisotopes - administration & dosage | Radionuclide Imaging | Salivary Glands - physiopathology | Submandibular Gland - physiopathology | Submandibular Gland Diseases - physiopathology | Aged | Radiopharmaceuticals - adverse effects | Submandibular Gland Diseases - etiology | Xerostomia - etiology | Dose-Response Relationship, Radiation | Xerostomia - diagnostic imaging | Radiopharmaceuticals - therapeutic use | Index Medicus
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5. Full Text Predictors of outcomes in large cell undifferentiated carcinoma of the major salivary glands
by Schrank, Travis P and Zhan, Kevin Y and Lentsch, Eric J
The Laryngoscope, ISSN 0023-852X, 02/2017, Volume 127, Issue 2, pp. 372 - 376
Objective: Major salivary gland large-cell undifferentiated carcinoma (LCUC) is rare and has a poor prognosis. Characterization of patient demographics, tumor... 
undifferentiated carcinoma | salivary gland cancer | Large cell undifferentiated carcinoma | parotid cancer | SURGERY | MEDICINE, RESEARCH & EXPERIMENTAL | OTORHINOLARYNGOLOGY | MALIGNANT PAROTID TUMORS | RADIOTHERAPY | CANCER | Salivary Gland Neoplasms - mortality | Sublingual Gland Neoplasms - mortality | Prognosis | Follow-Up Studies | Carcinoma, Large Cell - pathology | Humans | Middle Aged | Male | Carcinoma, Large Cell - mortality | Sublingual Gland Neoplasms - therapy | Submandibular Gland Neoplasms - diagnosis | Aged, 80 and over | Parotid Neoplasms - therapy | Adult | Female | Sublingual Gland Neoplasms - pathology | Sublingual Gland Neoplasms - diagnosis | Submandibular Gland Neoplasms - therapy | Submandibular Gland Neoplasms - pathology | Carcinoma, Large Cell - diagnosis | Kaplan-Meier Estimate | Combined Modality Therapy | Submandibular Gland Neoplasms - mortality | Salivary Gland Neoplasms - diagnosis | Parotid Neoplasms - mortality | Parotid Neoplasms - diagnosis | Salivary Gland Neoplasms - therapy | Parotid Neoplasms - pathology | Aged | Neoplasm Staging | Salivary Gland Neoplasms - pathology | Carcinoma, Large Cell - therapy | Carcinoma | Metastasis | Comorbidity | Patient outcomes | Analysis | Cancer | Survival analysis | Medical prognosis | Index Medicus
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6. Full Text Initial stages of development of the submandibular gland (human embryos at 5.5–8 weeks of development)
by Quirós‐Terrón, Luis and Arráez‐Aybar, Luis‐Alfonso and Murillo‐González, Jorge and De‐la‐Cuadra‐Blanco, Crótida and Martínez‐Álvarez, María‐Concepción and Sanz‐Casado, José‐Vicente and Mérida‐Velasco, José‐Ramón
Journal of Anatomy, ISSN 0021-8782, 05/2019, Volume 234, Issue 5, pp. 700 - 708
The aim of this study was to determine the main stages of submandibular salivary gland development during the embryonic period in humans. In addition, we... 
development | embryology | submandibular salivary gland | embryonic stage | MORPHOGENESIS | ANATOMY & MORPHOLOGY | MICE | SALIVARY-GLANDS | CELL | Monoclonal antibodies | Embryonic development | Mesenchyme | Innervation | Blood vessels | Submandibular gland | Parenchyma | Salivary gland | Epithelium | Condensation | Embryogenesis | Lingual nerve | Developmental stages | Parasympathetic nervous system
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7. Full Text Multimodal ultrasonographic characterisation of parotid gland lesions—A pilot study
by Knopf, Andreas and Mansour, Naglaa and Chaker, Adam and Bas, Murat and Stock, Konrad
European Journal of Radiology, ISSN 0720-048X, 2012, Volume 81, Issue 11, pp. 3300 - 3305
Abstract Objectives Lesions of the major salivary glands represent a heterogeneous group comprising infectious, autoimmune, and neoplastic disorders. The... 
Radiology | Head and neck | B-mode | Parotid gland | Colour duplex | Ultrasonography | CEUS | DIAGNOSIS | HEAD | SUBMANDIBULAR-GLANDS | MICROCIRCULATION | TUMORS | ULTRASOUND | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Reproducibility of Results | Parotid Diseases - diagnosis | Humans | Image Interpretation, Computer-Assisted - methods | Middle Aged | Ultrasonography, Doppler, Color - methods | Male | Subtraction Technique | Elasticity Imaging Techniques - methods | Pilot Projects | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Aged | Index Medicus
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8. Full Text Ae4 (Slc4a9) anion exchanger drives Cl - uptake-dependent fluid secretion by mouse submandibular gland acinar cells
by Peña-Münzenmayer, Gaspar and Catalán, Marcelo A and Kondo, Yusuke and Jaramillo, Yasna and Liu, Frances and Shull, Gary E and Melvin, James E
Journal of Biological Chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 17, pp. 10677 - 10688
Transcellular Cl- movement across acinar cells is the rate-limiting step for salivary gland fluid secretion. Basolateral Nkcc1 Na+-K+-2Cl(-) cotransporters... 
CL-/HCO3-EXCHANGER | TARGETED DISRUPTION | ION-TRANSPORT | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRACELLULAR PH | COTRANSPORTER | INTERCALATED CELLS | SALIVARY-GLAND | UP-REGULATION | MICE LACKING | HCO3 | Acinar Cells - metabolism | Chloride-Bicarbonate Antiporters - genetics | Mice, Inbred C57BL | Submandibular Gland - metabolism | Saliva - secretion | Submandibular Gland - secretion | Male | Mice, 129 Strain | Chloride-Bicarbonate Antiporters - deficiency | Mice, Knockout | Chloride-Bicarbonate Antiporters - metabolism | Animals | Chlorides - metabolism | Submandibular Gland - cytology | Bicarbonates - metabolism | Female | Ion Transport | Mice | Acinar Cells - secretion | Cyclic AMP - metabolism | Index Medicus | Bicarbonate | Exchanger | Secretion | Membrane Biology | Chloride Transport | Epithelium | Salivary Gland
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9. Full Text Evaluation of Sialendoscopy-Assisted Treatment of Submandibular Gland Stones
by Xiao, Jin-Qing, MS and Sun, Hai-Jiang, MS and Qiao, Qi-Hui, MS and Bao, Xin, MS and Wu, Chuan-Bin, MS and Zhou, Qing, DDS, PhD
Journal of Oral and Maxillofacial Surgery, ISSN 0278-2391, 2016, Volume 75, Issue 2, pp. 309 - 316
Purpose The aim of the present study was to evaluate the therapeutic efficiency of sialendoscopy-assisted operations in the treatment of submandibular gland... 
Surgery | MANAGEMENT | LINGUAL NERVE | MORBIDITY | DENTISTRY, ORAL SURGERY & MEDICINE | INTRAORAL REMOVAL | EXPERIENCE | TRANSORAL REMOVAL | EXCISION | SALIVARY CALCULI | SIALODOCHOPLASTY | FLOW | Salivary Gland Calculi - diagnostic imaging | Submandibular Gland Diseases - pathology | Humans | Middle Aged | Salivary Gland Calculi - diagnosis | Submandibular Gland Diseases - diagnosis | Submandibular Gland Diseases - diagnostic imaging | Endoscopy - methods | Salivary Gland Calculi - pathology | Male | Tomography, X-Ray Computed | Salivary Gland Calculi - surgery | Young Adult | Submandibular Gland - pathology | Submandibular Gland - diagnostic imaging | Adult | Female | Submandibular Gland - surgery | Submandibular Gland Diseases - surgery | Medical colleges | Research institutes | Health aspects | Analysis | Index Medicus | Abridged Index Medicus | Dentistry
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10. Full Text Trans-Oral Robotic Surgery of Submandibular Gland Removal With Preservation of Sublingual Gland and Wharton's Duct
by Lin, Xiaozhen and Liang, Limin and Shao, Xiaojun and Han, Xiaodong
The Journal of craniofacial surgery, ISSN 1049-2275, 01/2019, Volume 30, Issue 1, pp. 237 - 238
In surgical removal of a submandibular gland, transcervical approach has esthetic problem and existing trans-oral approaches are extensively invasive. The... 
SURGERY | Intra-oral | SERIES | RESECTION | INTRAORAL REMOVAL | EXCISION | submandibular gland | robotic surgery | Robotic surgery | Physiological aspects | Salivary glands | Patient outcomes | Methods | Oral surgery | Dentistry
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11. Full Text Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells
by Romanenko, Victor G and Catalán, Marcelo A and Brown, David A and Putzier, Ilva and Hartzell, H. Criss and Marmorstein, Alan D and Gonzalez-Begne, Mireya and Rock, Jason R and Harfe, Brian D and Melvin, James E
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 17, pp. 12990 - 13001
Activation of an apical Ca2+-dependent Cl- channel (CaCC) is the rate-limiting step for fluid secretion in many exocrine tissues. Here, we compared the... 
CONDUCTANCE | FLUID SECRETION | DUCT CELLS | BESTROPHIN | ACTIVATED CHLORIDE CHANNEL | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGULATED ANION CHANNELS | VOLUME | EXPRESSION | FAMILY | Anoctamin-1 | Calcium - metabolism | Submandibular Gland - metabolism | Gene Expression Regulation - physiology | Chloride Channels - genetics | Mice, Knockout | Chloride Channels - metabolism | Animals | Chlorides - metabolism | Submandibular Gland - cytology | Mice | Ion Transport - physiology | Organ Specificity - physiology | Index Medicus | NaCl Absorption | Chloride Channels | Knock-out Mice | Secretion | Membrane Biology | Calcium Dependence | Chloride Transport | Epithelium | Salivary Gland
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12. Full Text Preoperative evaluation and surgical planning of submandibular gland tumors
by Atula, Timo and Panigrahi, Juha and Tarkkanen, Jussi and Mäkitie, Antti and Aro, Katri
Head & Neck, ISSN 1043-3074, 06/2017, Volume 39, Issue 6, pp. 1071 - 1077
Background Roughly half of submandibular gland neoplasms are malignant. Because preoperative information on the nature of these tumors remains limited, both... 
salivary gland | cytology | treatment | frozen section biopsy | fine‐needle aspiration | fine-needle aspiration | SURGERY | HEAD | METAANALYSIS | PROGNOSTIC-FACTORS | LESIONS | DIAGNOSTIC-ACCURACY | FINE-NEEDLE-ASPIRATION | LYMPH-NODE METASTASIS | PLEOMORPHIC ADENOMA | OTORHINOLARYNGOLOGY | ADENOID CYSTIC CARCINOMA | ELECTIVE NECK DISSECTION | Immunohistochemistry | Biopsy, Fine-Needle - methods | Prognosis | Carcinoma, Squamous Cell - pathology | Humans | Image-Guided Biopsy - methods | Middle Aged | Carcinoma, Squamous Cell - surgery | Male | Patient Care Planning | Submandibular Gland Neoplasms - surgery | Carcinoma, Squamous Cell - mortality | Neoplasm Invasiveness - pathology | Adenoma, Pleomorphic - surgery | Adult | Female | Retrospective Studies | Submandibular Gland - surgery | Submandibular Gland Neoplasms - pathology | Risk Assessment | Ultrasonography, Doppler | Treatment Outcome | Submandibular Gland Neoplasms - mortality | Adenoma, Pleomorphic - mortality | Disease-Free Survival | Submandibular Gland - pathology | Adenoma, Pleomorphic - pathology | Finland | Survival Analysis | Aged | Cohort Studies | Preoperative Care - methods | Tumors | Cellular biology | Surgery | Benign | Cytology | Submandibular gland | Malignancy | Neck | Ultrasound | Index Medicus
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13. Full Text Acinar cell response to liquid diet during rats’ growth period differs in submandibular and sublingual glands from that in parotid glands
by Takahashi, Shigeru and Uekita, Hiroki and Taniwaki, Hiroto and Domon, Takanori
Tissue and Cell, ISSN 0040-8166, 2017, Volume 49, Issue 2, pp. 275 - 284
Highlights • We studied effects of a liquid diet on submandibular and sublingual glands of growing rats. • In our study, acinar cells were unaffected in... 
Advanced Basic Science | Submandibular gland | Acinar cell | Growth | Sublingual gland | Liquid diet | GROWING RATS | APOPTOSIS | ATROPHY | ANATOMY & MORPHOLOGY | SENSITIVITY | MAJOR SALIVARY-GLANDS | CELL BIOLOGY | CONSISTENCY | TEMPOROMANDIBULAR-JOINT | PARASYMPATHECTOMY | SECRETION | MASTICATION | Sublingual Gland - ultrastructure | Acinar Cells - metabolism | Acinar Cells - ultrastructure | Caspase 3 - metabolism | Submandibular Gland - metabolism | Rats | Submandibular Gland - growth & development | Parotid Gland - ultrastructure | Parotid Gland - growth & development | Sublingual Gland - metabolism | Animals | Diet | Sublingual Gland - growth & development | Bromodeoxyuridine - chemistry | Submandibular Gland - ultrastructure | Parotid Gland - metabolism | Acinar cells | Tissue | Parotid gland | Rodents | Antibodies | Caspase | Effects | Experiments | Caspase-3 | Index Medicus
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14. Full Text The Human Submandibular Gland
: Immunohistochemical Analysis of SNAREs and Cytoskeletal Proteins
by Stoeckelhuber, Mechthild and Scherer, Elias Q and Janssen, Klaus-Peter and Slotta-Huspenina, Julia and Loeffelbein, Denys J and Rohleder, Nils H and Nieberler, Markus and Hasler, Rafael and Kesting, Marco R
Journal of Histochemistry & Cytochemistry, ISSN 0022-1554, 2/2012, Volume 60, Issue 2, pp. 110 - 120
Submandibular acinar glands secrete numerous proteins such as digestive enzymes and defense proteins on the basis of the exocrine secretion mode. Exocytosis is... 
salivary glands | secretory pathway | exocytosis | immunohistochemistry | cytoskeleton | PAROTID ACINAR-CELLS | RBL-2H3 MAST-CELLS | ADRENAL CHROMAFFIN CELLS | MEMBRANE-PROTEIN | ELECTRON-MICROSCOPY | ACTIN-FILAMENTS | SALIVARY-GLANDS | PLASMA-MEMBRANE | CELL BIOLOGY | EPITHELIAL-CELLS | VESICLE EXOCYTOSIS | Cytoskeletal Proteins - analysis | Immunohistochemistry | SNARE Proteins - analysis | Humans | Middle Aged | Child, Preschool | Male | Submandibular Gland - chemistry | Young Adult | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Microscopy, Fluorescence | Index Medicus
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