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Clinical Chemistry, ISSN 0009-9147, 08/2009, Volume 55, Issue 8, pp. 1555 - 1558
BACKGROUND: Influenza A viruses are medically important viral pathogens that cause significant mortality and morbidity throughout the world. The recent... 
SWINE INFLUENZA | MEDICAL LABORATORY TECHNOLOGY | Influenza A Virus, H2N2 Subtype - isolation & purification | Molecular Diagnostic Techniques - methods | Influenza A Virus, H1N1 Subtype - classification | Humans | DNA, Viral - analysis | Influenza A Virus, H5N1 Subtype - classification | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Molecular Diagnostic Techniques - economics | Influenza A Virus, H5N1 Subtype - isolation & purification | Reverse Transcriptase Polymerase Chain Reaction - economics | RNA, Viral - genetics | Influenza A Virus, H1N1 Subtype - isolation & purification | Influenza A Virus, H3N2 Subtype - isolation & purification | Time Factors | Base Sequence | Reverse Transcriptase Polymerase Chain Reaction - methods | Sensitivity and Specificity | Influenza, Human - diagnosis | Influenza, Human - virology | RNA, Viral - isolation & purification | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - classification | RNA, Viral - analysis | Influenza A Virus, H2N2 Subtype - classification | Orthomyxoviridae Infections - diagnosis | Animals | Influenza A Virus, H2N2 Subtype - genetics | DNA, Viral - genetics | Orthomyxoviridae Infections - virology | Swine - virology | Influenza viruses | Polymerase chain reaction | Usage | Swine influenza | Causes of | Genetic aspects | Research | Diagnosis | Health aspects | Viruses | Mathematical models | Microbiology | Swine flu | Laboratories | Influenza A Virus, H3N2 Subtype | Influenza A Virus, H2N2 Subtype | Influenza A Virus, H5N1 Subtype | Reverse Transcriptase Polymerase Chain Reaction | Virology | Life Sciences | Microbiology and Parasitology | Molecular Diagnostic Techniques | Swine | RNA, Viral | Influenza, Human | Influenza A Virus, H1N1 Subtype | Orthomyxoviridae Infections | DNA, Viral
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 22, pp. 8107 - 8112
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the... 
H1N1 subtype influenza A virus | Pandemics | Influenza A virus | Swine | Mortality | Childhood | Antibodies | Viruses | Immunity | Age groups | Pathogenicity | Cohort immunity | Phylogeny | Reassortment | Virulence | UNITED-STATES | MORTALITY | reassortment | ORIGINAL ANTIGENIC SIN | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | HUMAN SERA | PATTERNS | cohort immunity | pathogenicity | RESPONSES | DIFFERENT AGES | virulence | phylogeny | INFECTION | EPIDEMIOLOGY | Influenza A Virus, H1N1 Subtype - immunology | Reassortant Viruses - pathogenicity | Humans | Influenza A virus - genetics | Reassortant Viruses - genetics | Disease Resistance - immunology | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Influenza A Virus, H3N8 Subtype - genetics | Influenza A Virus, H3N8 Subtype - pathogenicity | Influenza A Virus, H7N9 Subtype - immunology | Genetic Variation | Reassortant Viruses - immunology | Influenza A Virus, H7N9 Subtype - pathogenicity | Influenza A virus - pathogenicity | Influenza, Human - mortality | Adult | Influenza A virus - immunology | Influenza, Human - virology | Child | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza Pandemic, 1918-1919 - mortality | Birds | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H3N2 Subtype - immunology | Biological Evolution | Animals | Influenza A Virus, H3N8 Subtype - immunology | Influenza A Virus, H5N1 Subtype - immunology | Influenza A Virus, H5N1 Subtype - pathogenicity | Aged | Influenza A Virus, H7N9 Subtype - genetics | Causes of | Epidemics | United States | Swine influenza | Biological Sciences
Journal Article
Trends in Immunology, ISSN 1471-4906, 2009, Volume 30, Issue 12, pp. 574 - 584
Avian influenza A H5N1 remains unusual in its virulence for humans. Although infection of humans remains inefficient, many of those with H5N1 disease have a... 
Allergy and Immunology | BRONCHIAL EPITHELIAL-CELLS | CYTOKINE RESPONSES | DENDRITIC CELLS | I INTERFERON RESPONSE | LOWER RESPIRATORY-TRACT | ACUTE LUNG INJURY | PROINFLAMMATORY CYTOKINES | IMMUNOLOGY | STRAND RNA VIRUSES | HONG-KONG | H1N1 VIRUS | Influenza A Virus, H1N1 Subtype - immunology | Tumor Necrosis Factor-alpha - metabolism | Influenza, Human - pathology | Orthomyxoviridae Infections - physiopathology | Humans | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Immunity, Innate | Influenza A Virus, H3N2 Subtype - immunology | Respiratory Distress Syndrome, Adult - immunology | Animals | Influenza A Virus, H5N1 Subtype - immunology | Interferons - metabolism | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Influenza, Human - physiopathology | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Avian influenza | Influenza viruses | Immune response | Health aspects | Analysis | Infections | Pandemics | Mutation | Respiratory distress syndrome | Genes | Influenza A Virus, H3N2 Subtype | Respiratory Distress Syndrome, Adult | Interferons | Influenza A Virus, H5N1 Subtype | Tumor Necrosis Factor-alpha | Virology | Life Sciences | Microbiology and Parasitology | Influenza, Human | Influenza A Virus, H1N1 Subtype | Orthomyxoviridae Infections | influenza | cytokine | H5N1 | macrophage | pandemic | innate immune response
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 12/2016, Volume 20, Issue 6, pp. 810 - 821
Constant surveillance of live poultry markets (LPMs) is currently the best way to predict and identify emerging avian influenza viruses (AIVs) that pose a... 
genesis | prevalence | live poultry markets | H5N6 avian influenza | resassortment | evolution | birds | human infection | HUMAN INFECTION | H7N9 VIRUS | MICROBIOLOGY | SHORT READ ALIGNMENT | HONG-KONG | ORIGIN | LIVE POULTRY MARKETS | VIROLOGY | H9N2 | A(H5N6) VIRUS | A VIRUSES | MIGRATORY BIRDS | PARASITOLOGY | Public Health | Prevalence | Humans | Chickens - virology | Geographic Mapping | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H9N2 Subtype - pathogenicity | Phylogeny | RNA, Viral - genetics | Genes, Viral - genetics | Poultry - virology | Base Sequence | Influenza A Virus, H7N9 Subtype - pathogenicity | Hemagglutinins | Influenza, Human - virology | Agriculture | Genome, Viral | Influenza A Virus, H5N8 Subtype - pathogenicity | Influenza A Virus, H9N2 Subtype - genetics | Influenza A Virus, H5N8 Subtype - classification | Ducks - virology | Columbidae - virology | Genotype | Influenza, Human - epidemiology | Geese - virology | Influenza in Birds - epidemiology | China - epidemiology | Animals | Epidemiological Monitoring | Influenza in Birds - virology | Neuraminidase | Reassortant Viruses | Influenza A Virus, H5N1 Subtype - pathogenicity | Influenza A Virus, H5N8 Subtype - genetics | Influenza A Virus, H7N9 Subtype - genetics | Cities | Influenza A Virus, H5N8 Subtype - isolation & purification | Evolution, Molecular | Virus diseases | Avian influenza | Cladistic analysis | Analysis | Lectins | Avian influenza viruses | Health aspects
Journal Article
Virology Journal, ISSN 1743-422X, 2013, Volume 10, Issue 1, pp. 10:23 - 23
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 2/2012, Volume 205, Issue 3, pp. 474 - 485
Host innate immunity is the first line of defense against invading pathogens, including influenza viruses.Ferrets are well recognized as the best model of... 
Inoculation | Disease transmission | Messenger RNA | Cytokines | Viruses | Orthomyxoviridae | Innate immunity | Infections | H5N1 subtype influenza A virus | Human influenza | UNITED-STATES | INFECTIOUS DISEASES | A H5N1 VIRUS | MICROBIOLOGY | CYTOKINE | SYMPTOMS | INDUCTION | IMMUNOLOGY | ALPHA-INTERFERON | SEASONAL INFLUENZA | DISEASE | INFECTION | EXPRESSION | Influenza A Virus, H1N1 Subtype - immunology | Influenza A Virus, H3N2 Subtype - pathogenicity | Orthomyxoviridae Infections - pathology | Virulence | Influenza A Virus, H1N1 Subtype - pathogenicity | Male | Gene Expression Profiling | Virus Shedding | Ferrets | Immunity, Innate | Influenza A Virus, H3N2 Subtype - immunology | Respiratory System - virology | Animals | Orthomyxoviridae Infections - transmission | Influenza A Virus, H5N1 Subtype - immunology | Influenza A Virus, H5N1 Subtype - pathogenicity | Orthomyxoviridae Infections - virology | Cytokines - biosynthesis | Orthomyxoviridae Infections - immunology | Respiratory System - immunology | Disease Models, Animal | Influenza viruses | Physiological aspects | Immune response | Research | Influenza A Virus, H3N2 Subtype | Respiratory System | Influenza A Virus, H5N1 Subtype | Life Sciences | Human health and pathology | Infectious diseases | Influenza A Virus, H1N1 Subtype | Orthomyxoviridae Infections
Journal Article
Journal of General Virology, ISSN 0022-1317, 08/2015, Volume 96, Issue 8, pp. 2036 - 2049
Journal Article
Virology, ISSN 0042-6822, 2011, Volume 422, Issue 1, pp. 151 - 160
Abstract Swine influenza viruses (SIV) have been recognized as important pathogens for pigs and occasional human infections with swine origin influenza viruses... 
Infectious Disease | Triple reassortants | Swine origin influenza viruses | PIGS | PATHOGENESIS | TRANSMISSION | PROTEIN | VIROLOGY | A VIRUSES | PB1-F2 | INFECTION | PREVALENCE | Influenza A Virus, H1N1 Subtype - immunology | Influenza A Virus, H1N1 Subtype - classification | United States | Humans | Neuraminidase - genetics | Reassortant Viruses - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Neuraminidase - immunology | Genetic Variation | Influenza A Virus, H1N2 Subtype - genetics | Antigens, Viral | Influenza A Virus, H1N1 Subtype - isolation & purification | Influenza A Virus, H3N2 Subtype - isolation & purification | Base Sequence | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Genome, Viral | Influenza A Virus, H3N2 Subtype - classification | Influenza, Human - epidemiology | Influenza A Virus, H1N2 Subtype - immunology | Influenza A Virus, H3N2 Subtype - immunology | Reassortant Viruses - isolation & purification | Sequence Analysis, DNA | Molecular Epidemiology | Influenza A Virus, H1N2 Subtype - isolation & purification | Influenza A Virus, H1N2 Subtype - classification | Influenza viruses | Genetic research | Genetic aspects | Swine | Influenza | Genes | Analysis | Infection | Pathogens | Genetic analysis | Swine influenza
Journal Article
Science, ISSN 0036-8075, 3/2006, Volume 311, Issue 5767, pp. 1576 - 1580
The spread of H5N1 avian influenza viruses (AIVs) from China to Europe has raised global concern about their potential to infect humans and cause a pandemic.... 
Proteins | Pandemics | Swine | Neurons | Horses | Viruses | Amino acids | Genomes | Signatures | Genotypes | Research Article | CELLS | RESPONSES | NS1 PROTEIN | GENE | RECOGNITION | PDZ DOMAINS | MULTIDISCIPLINARY SCIENCES | VIRUSES | Influenza A virus - chemistry | Virulence Factors - genetics | Humans | Influenza A virus - genetics | Molecular Sequence Data | Reassortant Viruses - genetics | Influenza A Virus, H5N2 Subtype - genetics | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Influenza A Virus, H3N8 Subtype - genetics | Viral Nonstructural Proteins - chemistry | RNA, Viral - genetics | Genes, Viral | Influenza A virus - pathogenicity | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Genome, Viral | Influenza A Virus, H9N2 Subtype - genetics | Viral Proteins - chemistry | Computational Biology | Birds - virology | Viral Nonstructural Proteins - genetics | Viral Proteins - genetics | Influenza A virus - isolation & purification | Virulence Factors - chemistry | Sequence Analysis, DNA | Animals | Influenza A Virus, H2N2 Subtype - genetics | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - chemistry | Influenza A Virus, H5N1 Subtype - pathogenicity | Influenza A Virus, H7N7 Subtype - genetics | Mutation | Avian influenza | Research | Analysis | Influenza research
Journal Article
Journal of Virology, ISSN 0022-538X, 02/2014, Volume 88, Issue 3, pp. 1684 - 1693
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2008, Volume 105, Issue 11, pp. 4381 - 4386
The virulence of influenza virus is a multigenic trait. One determinant of virulence is the multifunctional NS1 protein that functions in several ways to... 
Proteins | H1N1 subtype influenza A virus | Lungs | Influenza A virus | Virulence | Viruses | Orthomyxoviridae | Amino acids | H5N1 subtype influenza A virus | Genetic mutation | PDZ domains | Influenza reverse genetics | PDZ ligand | H5N1 influenza | Mouse model for influenza | 1918 PANDEMIC VIRUS | ACTIVATION | BETA INDUCTION | MULTIDISCIPLINARY SCIENCES | PRE-MESSENGER-RNAS | NUCLEAR EXPORT | A-VIRUS | INTERFERON | IN-VIVO | mouse model for influenza | INFECTED-CELLS | influenza reverse genetics | V-PROTEIN | Interferons - biosynthesis | Lung Diseases - metabolism | Virulence Factors - genetics | Humans | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Viral Nonstructural Proteins - chemistry | Recombination, Genetic - genetics | Female | Influenza A Virus, H5N1 Subtype - metabolism | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H1N1 Subtype - metabolism | Disease Models, Animal | Amino Acid Sequence | Cell Line | Viral Nonstructural Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Virulence Factors - chemistry | Mutation - genetics | Animals | Dogs | Influenza A Virus, H5N1 Subtype - chemistry | Influenza A Virus, H5N1 Subtype - pathogenicity | Viral Nonstructural Proteins - metabolism | Virulence Factors - metabolism | Influenza A Virus, H1N1 Subtype - chemistry | Mice | Mice, Inbred BALB C | Lung Diseases - pathology | Ligand binding (Biochemistry) | Viral proteins | Influenza | Influence | Models | Genetic aspects | Virulence (Microbiology) | Research | Properties | Biological Sciences
Journal Article