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06/2011
Aberrant DNA synthesis and maintenance have been implicated in numerous human diseases. I describe here a novel strategy for systematically identifying budding... 
High-content screening | 0369 | Budding yeast | Rad52 | 0379 | DNA damage foci | Genomics | Synthetic genetic array analysis | DNA repair
Dissertation
Journal of Bacteriology, ISSN 0021-9193, 10/2017, Volume 199, Issue 20
Genetic redundancy can obscure phenotypic effects of single-gene mutations. Two individual mutations may be viable separately but are lethal when combined,... 
Conjugation | Iron utilization pathways | Mycobacteria | RecA | Synthetic genetic array | SURVIVAL | TUBERCULOSIS | MICROBIOLOGY | iron utilization pathways | IRON | synthetic genetic array | IDENTIFICATION | conjugation | CHROMOSOMAL DNA | Mycobacterium | Genome-wide association studies | Usage | Gene mutations | Reports | Research
Journal Article
Genetics, ISSN 0016-6731, 07/2018, Volume 209, Issue 3, pp. 637 - 650
Journal Article
Science, ISSN 0036-8075, 12/2001, Volume 294, Issue 5550, pp. 2364 - 2368
In Saccharomyces cerevisiae, more than 80% of the ∼6200 predicted genes are nonessential, implying that the genome is buffered from the phenotypic consequences... 
Yeasts | Microbial genetics | Cell growth | Diploidy | Molecular genetics | Cell walls | DNA | Actins | Reports | Genetic mutation | Genetic screening | MORPHOGENESIS | SCREEN | BUDDING YEAST | SYNTHETIC LETHAL | MULTIDISCIPLINARY SCIENCES | ACTIN CYTOSKELETON | MUTATIONS | SACCHAROMYCES-CEREVISIAE | Cytoskeletal Proteins | Cell Polarity | Mitosis | Saccharomyces cerevisiae - genetics | Microtubule Proteins - physiology | Databases, Genetic | Endodeoxyribonucleases - physiology | Robotics | DNA, Fungal - biosynthesis | Genome, Fungal | RecQ Helicases | Recombination, Genetic | Gene Deletion | Cell Cycle Proteins - genetics | Microtubule Proteins - genetics | DNA Helicases - genetics | Genes, Fungal - physiology | Carrier Proteins - physiology | Saccharomyces cerevisiae - physiology | Computational Biology | Fungal Proteins - genetics | Genetic Markers | Saccharomyces cerevisiae Proteins - genetics | Genetic Techniques | Genes, Essential | Carrier Proteins - genetics | Endodeoxyribonucleases - genetics | Fungal Proteins - physiology | Microfilament Proteins | DNA Repair | Flap Endonucleases | Cytoskeleton - physiology | Saccharomyces cerevisiae Proteins - physiology | Cell Cycle Proteins - physiology | Saccharomyces cerevisiae - growth & development | Crosses, Genetic | DNA Helicases - physiology | Yeast | Gene mutations | Analysis | Genetic research | Genetic aspects | Research | Genetics | Mutation
Journal Article
Journal Article
G3-GENES GENOMES GENETICS, ISSN 2160-1836, 05/2017, Volume 7, Issue 5, pp. 1539 - 1549
Providing access to quantitative genomic data is key to ensure large-scale data validation and promote new discoveries. TheCellMap. org serves as a central... 
ANNOTATION ERRORS | LOCALIZATION | INTERACTION MAP | SYSTEMATIC IDENTIFICATION | genetic network | DELETION | SACCHAROMYCES-CEREVISIAE GENOME | MUTANTS | yeast genetics | synthetic genetic array SGA | GENETICS & HEREDITY | MISSING HERITABILITY | ONTOLOGY | genetic interactions | CELL
Journal Article
Journal Article