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Retrovirology, ISSN 1742-4690, 04/2010, Volume 7, Issue 1, pp. 34 - 34
The human immunodeficiency virus-1 (HIV-1) is a member of the lentivirus genus. The virus does not rely exclusively on the host cell machinery, but also on... 
OXIDE SYNTHASE EXPRESSION | TUMOR-NECROSIS-FACTOR | T-CELL APOPTOSIS | VIROLOGY | AIDS-DEMENTIA-COMPLEX | ENVELOPE GLYCOPROTEIN GP120 | CHEMOKINE RECEPTOR CXCR4 | PERIPHERAL-BLOOD MONOCYTES | HUMAN-IMMUNODEFICIENCY-VIRUS | NF-KAPPA-B | TYPE-1 TAT PROTEIN | HIV-1 - pathogenicity | Signal Transduction | Virulence Factors - physiology | HIV Infections - virology | Humans | nef Gene Products, Human Immunodeficiency Virus - physiology | vpr Gene Products, Human Immunodeficiency Virus - physiology | vpr Gene Products, Human Immunodeficiency Virus - immunology | Virulence Factors - immunology | Macrophage Activation | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | tat Gene Products, Human Immunodeficiency Virus - physiology | nef Gene Products, Human Immunodeficiency Virus - immunology | HIV Envelope Protein gp120 - physiology | tat Gene Products, Human Immunodeficiency Virus - immunology | Macrophages - immunology | Viral proteins | Cellular signal transduction | Genetic aspects | Research | Genetic transcription | Health aspects | HIV infection | Risk factors | HIV Infections | HIV-1 | tat Gene Products, Human Immunodeficiency Virus | vpr Gene Products, Human Immunodeficiency Virus | HIV Envelope Protein gp120 | Macrophages | Virulence Factors | Life Sciences | Human health and pathology | Infectious diseases | nef Gene Products, Human Immunodeficiency Virus
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2007, Volume 13, Issue 1, pp. 100 - 106
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23293
HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of... 
REPLICATION | PHOSPHORYLATION | TAT | MULTIDISCIPLINARY SCIENCES | KINASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | SH3 DOMAINS | SHORT LINEAR MOTIFS | BINDING | VIRAL-INFECTION | NEF | rev Gene Products, Human Immunodeficiency Virus - chemistry | Humans | env Gene Products, Human Immunodeficiency Virus - metabolism | rev Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - chemistry | tat Gene Products, Human Immunodeficiency Virus - chemistry | CREB-Binding Protein - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - chemistry | Databases, Protein | nef Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Calmodulin - metabolism | Protein Structure, Secondary | tat Gene Products, Human Immunodeficiency Virus - genetics | Models, Molecular | gag Gene Products, Human Immunodeficiency Virus - chemistry | Binding Sites - genetics | Human Immunodeficiency Virus Proteins - metabolism | Proteins - genetics | Protein Interaction Mapping - methods | Proteins - metabolism | nef Gene Products, Human Immunodeficiency Virus - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Human Immunodeficiency Virus Proteins - genetics | rev Gene Products, Human Immunodeficiency Virus - genetics | Amino Acid Motifs - genetics | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Casein Kinase II - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | tat Gene Products, Human Immunodeficiency Virus - metabolism | Physiological aspects | Viral proteins | HIV (Viruses) | Genomics | Protein binding | Phenotypes | Phosphorylation | Hot spots | Crosstalk | Amino acid sequence | Viruses | Genomes | Kinases | Proteins | Conserved sequence | Human immunodeficiency virus--HIV | Computer applications | Mutation | Localization | Bioinformatics | Binding sites | HIV | Human immunodeficiency virus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 201 - 206
The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly,... 
PATHOGENESIS | LOCALIZES | COMPLEX | PROTEIN | BECLIN-1 | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | BINDING | Apoptosis Regulatory Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Humans | Cell Membrane Permeability | Molecular Sequence Data | Peptide Fragments - pharmacology | Membrane Proteins - pharmacology | Membrane Proteins - therapeutic use | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Beclin-1 | Amino Acid Sequence | HIV-1 - metabolism | Virus Replication - drug effects | Peptide Fragments - metabolism | HIV-1 - drug effects | tat Gene Products, Human Immunodeficiency Virus - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | West Nile virus - drug effects | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Chikungunya virus - drug effects | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Mice | HeLa Cells | Apoptosis Regulatory Proteins - therapeutic use | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Peptides | Microscopy | Rodents | Mortality | Amino acids | Infections | Autophagy
Journal Article
Journal of Virology, ISSN 0022-538X, 11/2003, Volume 77, Issue 21, pp. 11531 - 11535
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2017, Volume 13, Issue 7, p. e1006529
The ability to control lentivirus replication may be determined, in part, by the extent to which individual viral proteins are targeted by the immune system.... 
PROTECTION | CORRELATES ANALYSIS | MICROBIOLOGY | T-CELL RESPONSES | HIGHLY PATHOGENIC SIV | VIROLOGY | HIV | ENVELOPE | INFECTED-CELLS | VESICULAR STOMATITIS-VIRUS | DISCORDANT ASSOCIATIONS | NEUTRALIZATION | PARASITOLOGY | env Gene Products, Human Immunodeficiency Virus - immunology | SAIDS Vaccines - administration & dosage | HIV Infections - virology | Humans | Macaca mulatta | Rectum - immunology | HIV-1 - genetics | Rectum - virology | HIV Infections - immunology | SAIDS Vaccines - genetics | HIV-1 - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - genetics | Animals | HIV-1 - physiology | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Virus Replication | Antibodies, Viral - immunology | gag Gene Products, Human Immunodeficiency Virus - genetics | gag Gene Products, Human Immunodeficiency Virus - immunology | Disease Models, Animal | Simian Immunodeficiency Virus - immunology | Rhesus monkey | Control | AIDS vaccines | Usage | Immune response | Genetic aspects | Research | Simian immunodeficiency virus | Laboratories | Viremia | Funding | Chronic infection | Viruses | Infections | Vaccines | Loads (forces) | Proteins | Immunology | Gag protein | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Primates | Inserts | Localization | Research centers | Supervision | Immune system | Antigens | Medical research | Statistical analysis | Stability | Monkeys & apes | Pathology | Tat protein | Nef protein | Replication | Neutralization | Acquired immune deficiency syndrome | AIDS | Human immunodeficiency virus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2009, Volume 182, Issue 6, pp. 3718 - 3727
Previously, chronic-phase protection against SHIV89.6P challenge was significantly greater in macaques primed with replicating adenovirus type 5 host range... 
DEPENDENT CELLULAR CYTOTOXICITY | MEDIATED CYTOTOXICITY | CYTO-TOXICITY | NEF PROTEIN | HIV-1 TAT PROTEIN | DIFFERENT CLINICAL STAGES | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | T-CELLS | PASSIVE-IMMUNIZATION | DISEASE PROGRESSION | Vaccines, DNA - genetics | env Gene Products, Human Immunodeficiency Virus - immunology | Antiviral Agents - immunology | Humans | Vaccines, DNA - immunology | Antibody-Dependent Cell Cytotoxicity - immunology | Male | Neutralization Tests | Macaca mulatta | Vaccines, DNA - administration & dosage | Vaccinia virus - genetics | Vaccinia virus - immunology | Simian Acquired Immunodeficiency Syndrome - virology | env Gene Products, Human Immunodeficiency Virus - genetics | Adenoviridae - genetics | Female | tat Gene Products, Human Immunodeficiency Virus - immunology | Adenoviridae - immunology | Antibodies, Viral - biosynthesis | tat Gene Products, Human Immunodeficiency Virus - administration & dosage | Antibody-Dependent Cell Cytotoxicity - genetics | Binding Sites, Antibody - genetics | SAIDS Vaccines - administration & dosage | tat Gene Products, Human Immunodeficiency Virus - genetics | Cells, Cultured | Antiviral Agents - administration & dosage | Simian Acquired Immunodeficiency Syndrome - prevention & control | Antibodies, Viral - physiology | SAIDS Vaccines - genetics | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | env Gene Products, Human Immunodeficiency Virus - administration & dosage | Cell Line, Transformed
Journal Article
Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7299, pp. 747 - 751
Journal Article