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Cancer gene therapy, ISSN 0929-1903, 02/2019, Volume 26, Issue 7-8, pp. 257 - 257
All animal experiments were approved by the Animal Care and Use Committee (ACUC), Louisiana State University Health Science Center and not The People's... 
Temozolomide
Journal Article
Reference
Brain metastasis-evidence based management, 12/2006
Advances in cancer management have resulted in a significant increase in median survival of number of diseases. Consequently we are seeing more patients living... 
Brain Metastasis, Management, Temozolomide
Journal
The Journal of clinical endocrinology and metabolism, ISSN 0021-972X, 08/2018, Volume 103, Issue 8, pp. 3115 - 3118
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, pp. e0199076 - e0199076
We determine an optimal protocol for temozolomide using population variability and dynamic optimization techniques inspired by artificial intelligence. We use... 
BREAST-CANCER | TRIAL | PHARMACOKINETICS | ONCOLOGY | MULTIDISCIPLINARY SCIENCES | PRECISION MEDICINE | MODEL | METRONOMIC CHEMOTHERAPY | CHILDREN | Temozolomide - pharmacokinetics | Artificial Intelligence | Humans | Antineoplastic Agents, Alkylating - pharmacology | Treatment Outcome | Antineoplastic Agents, Alkylating - pharmacokinetics | Antineoplastic Agents, Alkylating - administration & dosage | Temozolomide - pharmacology | Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Dose-Response Relationship, Drug | Temozolomide - therapeutic use | Algorithms | Models, Biological | Temozolomide - administration & dosage | Neoplasms - pathology | Monte Carlo Method | Technology application | Usage | Temozolomide | Pharmacokinetics | Artificial intelligence | Testing | Physiological effects | Operations research | Toxicity | Brain cancer | Variability | Clinical trials | Oncology | Metastasis | Cancer therapies | Optimization | Confidence intervals | Population | Myelosuppression | Drug dosages | Monte Carlo method | Pharmacodynamics | Computer simulation | Search algorithms | Neutrophils | Periodicity | Pharmacology | Breast cancer | FDA approval | Periodic variations | Patients | Chemotherapy | Neural networks | Tumors | Index Medicus | Economies and finances | Humanities and Social Sciences
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 9, pp. 916 - 926
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 04/2019, Volume 9, Issue 4, pp. 469 - 471
In this issue, Maertens and colleagues demonstrate that HDAC3 inhibition potentiates the effects of MAPK pathway inhibitors in melanoma, including... 
ONCOLOGY | TEMOZOLOMIDE | Index Medicus
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 03/2013, Volume 31, Issue 7, pp. 977 - 978
Journal Article
JAMA, ISSN 0098-7484, 12/2017, Volume 318, Issue 23, pp. 2306 - 2316
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018
Temozolomide (TMZ) is currently the first-line drug used for clinical postoperative or non-surgical chemotherapy for glioma, but acquired and intrinsic... 
temozolomide | synergy | formononetin | glioma
Journal Article
Experimental Cell Research, ISSN 0014-4827, 02/2019, Volume 375, Issue 1, pp. 73 - 81
Glioblastoma multiforme (GBM) is the most malignant tumor of the central nervous system, and chemoresistance blunts the effect of temozolomide (TMZ) in the... 
YY1 | Stemness | Temozolomide | miR-7-5p | Glioblastoma
Journal Article
Annals of Oncology, ISSN 0923-7534, 08/2018, Volume 29, Issue 8, pp. 1628 - 1630
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2019, Volume 144, Issue 7, pp. 1735 - 1745
Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14–15 months after surgery, radiation and chemotherapy using temozolomide (TMZ).... 
temozolomide | glioblastoma | autophagy | drug resistance | thioridazine | SURVIVAL | ANGIOGENESIS | NEWLY-DIAGNOSED GLIOBLASTOMA | CONNECTIVITY MAP | CELLULAR-DISTRIBUTION | RADIATION | ADJUVANT TEMOZOLOMIDE | TRIAL | ONCOLOGY | RESISTANCE | TUMOR-GROWTH | Lysosomes - drug effects | Cell Survival - drug effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Brain Neoplasms - genetics | Thioridazine - administration & dosage | Synthetic Lethal Mutations | Brain Neoplasms - drug therapy | Autophagy - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Drug Synergism | Temozolomide - therapeutic use | Xenograft Model Antitumor Assays | Autophagosomes - drug effects | Animals | Glioblastoma - genetics | Temozolomide - administration & dosage | Thioridazine - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Glioblastoma - drug therapy | Drug Resistance, Neoplasm - drug effects | RNA | Genes | Brain tumors | Genomics | Drug resistance | Antineoplastic agents | Gene expression | Glioblastoma multiforme | Antimitotic agents | Chemotherapy | Analysis | Health aspects | Phenothiazine | Cancer | Brain | Neuroleptics | Toxicity | Brain cancer | Glioblastoma | Radiation | Phagosomes | Lysosomes | Genomes | Lethality | Drug development | Autophagy | Psychotropic drugs | Surgery | Biocompatibility | RNA-mediated interference | Feasibility studies | Pharmacology | Sensitivity | Thioridazine | Ribonucleic acids | Neural networks | Medical prognosis | Glioblastoma cells | Temozolomide | Phagocytosis | Tumors | Index Medicus
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 07/2017, Volume 118, Issue 7, pp. 1889 - 1899
In the present study, we have demonstrated that CASC2 plays an important role in the chemo‐resistance of glioma by functioning as a ceRNA to regulate the... 
PTEN | CASC2 | TEMOZOLOMIDE (TMZ) | miR‐181a | GLIOMA | CHEMO‐RESISTANCE | miR-181a | CHEMO-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | CERVICAL-CANCER | GASTRIC-CANCER CELLS | MESENCHYMAL TRANSITION | CELL BIOLOGY | LONG NONCODING RNA | SIGNALING PATHWAY | COLORECTAL-CANCER | TEMOZOLOMIDE TMZ | TARGETING PTEN | KIDNEY CANCER | Multivariate Analysis | Dacarbazine - therapeutic use | Humans | Middle Aged | Male | MicroRNAs - metabolism | Glioma - metabolism | Dacarbazine - pharmacology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Adult | Female | Real-Time Polymerase Chain Reaction | PTEN Phosphohydrolase - genetics | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Proportional Hazards Models | PTEN Phosphohydrolase - metabolism | RNA, Long Noncoding - genetics | Blotting, Western | Cell Line, Tumor | Protein Binding | Cell Proliferation - drug effects | MicroRNAs - genetics | In Vitro Techniques | RNA, Long Noncoding - metabolism | Glioma - drug therapy | Cell proliferation | Biotechnology | Cell survival | Brain tumors | Chemoresistance | AKT protein | Biochemistry | Biology | Tissues | Survival | Amplification | Sensitivity | Chemotherapy | Coding | Glioma cells | Cell lines | Regulatory mechanisms (biology) | Strategy | Tumorigenesis | Diagnosis | Inhibition | Temozolomide | PTEN protein | Cancer | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 06/2018, Volume 423, pp. 16 - 26
Chemotherapy is an important treatment for malignant tumors; however, its efficacy and clinical application are limited by its side effects and drug resistance... 
Photothermal therapy | Indocyanine green | Photodynamic therapy | Temozolomide | Melanoma | INDOCYANINE-GREEN | GENE DELIVERY | PHOTODYNAMIC TUMOR-THERAPY | DRUG-DELIVERY | CANCER-THERAPY | CHEMOTHERAPY | BREAST-CANCER | LUNG-CANCER | NANOPARTICLES | ONCOLOGY | IN-VIVO | Melanoma - metabolism | Cell Survival - drug effects | Polyamines - chemistry | Humans | Indocyanine Green | Temozolomide - chemistry | Temozolomide - pharmacology | Drug Delivery Systems | Nanoparticles | Xenograft Model Antitumor Assays | Animals | Temozolomide - administration & dosage | Hyaluronan Receptors - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Hyperthermia, Induced - methods | Melanoma - therapy | Medical colleges | Amines | Active oxygen | Drug resistance | Antineoplastic agents | Photochemotherapy | Antimitotic agents | Chemotherapy | Drug therapy | Hyaluronic acid | Tumors | Cancer | Drugs | Drug delivery systems | Nuclear magnetic resonance--NMR | Toxicity | Fluorescent dyes | Fluorescence | Cytotoxicity | Fluorescent indicators | Anticancer properties | Oxygen production | Temperature effects | CD44 antigen | Conflicts of interest | Infrared radiation | Biocompatibility | Physiology | Oxygen | Light irradiation | I.R. radiation | Light therapy | Phototherapy | Side effects | Singlet oxygen | Irradiation | Index Medicus
Journal Article
The Oncologist, ISSN 1083-7159, 06/2019, Volume 24, Issue 6, pp. 798 - 802
Thymic neuroendocrine tumors are rare malignant tumors of the anterior mediastinum and lack standard treatment options. This report analyzes the efficacy and... 
Thymic atypical carcinoid | Temozolomide | Neuroendocrine tumor | Capecitabine | SURVIVAL | NEUROENDOCRINE TUMORS | CAPECITABINE/TEMOZOLOMIDE | ONCOLOGY | CLASSIFICATION | SINGLE-CENTER
Journal Article
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