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Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 04/2019, Volume 29, Issue 8, pp. 986 - 990
Pretargeted nuclear imaging based on the ligation between tetrazines and nano-sized targeting agents functionalized with trans-cyclooctene (TCO) has recently... 
Carbon-11 | PET imaging | Trans-cyclooctene | Pretargeting | Tetrazine
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2019, Volume 29, Issue 8, pp. 986 - 990
Pretargeted nuclear imaging based on the ligation between tetrazines and nano-sized targeting agents functionalized with -cyclooctene (TCO) has recently been... 
Carbon-11 | PET imaging | Trans-cyclooctene | Pretargeting | Tetrazine
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 01/2020, Volume 1200, p. 127084
A series of functionalized pyridazine derivatives ( – ) 4-yl , 4-yl 4-yl , 3-yl 4-yl , 4-yl 2-yl , 4-yl 5 , 3-yl , 4-yl 3-yl , 3-yl , 3-yl 2-yl , 3-yl were... 
Anti-biotic | Diels-alder | Tetrazine | Pyridazine | Crystal | TETRAZINES | CHEMISTRY | CHEMISTRY, PHYSICAL
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 17, pp. 2461 - 2464
Polycyclic N-oxides were developed based on the heterocycles 1,2,4,5-tetrazine and 4H, 8H-difurazano[3,4-b:3',4'-e]pyrazine. The new compounds are energetic... 
CHEMISTRY | REDOX | CRYSTAL PACKING | TETRAZINE | CHEMISTRY, MULTIDISCIPLINARY | FUSED HETEROCYCLE
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 02/2019, Volume 55, Issue 17, pp. 2461 - 2464
Polycyclic N-oxides were developed based on the heterocycles 1,2,4,5-tetrazine and 4H,8H-difurazano[3,4-b:3',4'-e]pyrazine. The new compounds are energetic and... 
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 04/2019, Volume 55, Issue 31, pp. 4582 - 4585
We report the synthesis and use of sydnone-based profluorophores as tools for imaging applications. These new probes display exquisite reactivity towards... 
CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | TETRAZINE PROBES
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2019, Volume 58, Issue 37, pp. 12719 - 12719
Tetrazine can act as an effective singlet oxygen quencher of halogenated BODIPY photosensitizers. In their Communication on page 12868 ff., O. Vázquez and... 
bioorthogonal reactions | singlet oxygen | tetrazine | photodynamic therapy | BODIPY dyes
Journal Article
Dyes and Pigments, ISSN 0143-7208, 01/2020, Volume 172, p. 107865
Two series of new -tetrazine derivatives containing 1,3,4-oxadiazole and 1,3,4-thiadiazole rings were synthesized from -tetrazine-3,6-dicarbohydrazide,... 
Microwave | Cyclocondensation | 1,3,4-Thiadiazole | 1,3,4-Oxadiazole | Luminescence properties | s-Tetrazine | 1,2,4,5-TETRAZINE | TETRAZINE | MATERIALS SCIENCE, TEXTILES | SULFONE DERIVATIVES | 3D-QSAR | ENGINEERING, CHEMICAL | FLUORESCENCE | CHEMISTRY, APPLIED
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2012, Volume 51, Issue 21, pp. 5222 - 5225
Paving the way: The lack of convenient synthetic methods is a significant roadblock to the broader use of 1,2,4,5‐tetrazines in bioorthogonal chemistry and... 
bioorthogonal synthesis | cycloaddition | heterocycles | metal catalysis | tetrazines | ONE-STEP SYNTHESIS | COMPLEXES | LIGATION | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES | PROBES | AMINES | CHEMISTRY | Lewis acid | Hydrazines | Synthesis | Nitriles | Nickel | Paving | Zinc | Aliphatic compounds | catalysis | bioorthogonal | heterocycle | tetrazine
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 01/2017, Volume 53, Issue 8, pp. 1378 - 1380
Hydrogen sulfide (H2S) is an important biomolecule with high therapeutic potential. Here we leverage the inverse-electron demand Diels-Alder (IEDDA) click... 
DRUG | GASOTRANSMITTER | VIVO BIOORTHOGONAL CHEMISTRY | FLUORESCENT-PROBES | DONORS | MICE | TETRAZINE LIGATION | CHEMISTRY, MULTIDISCIPLINARY | LIVING CELLS
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 05/2018, Volume 51, Issue 5, pp. 1073 - 1081
Conspectus Chemical tools are transforming our understanding of biomolecules and living systems. Included in this group are bioorthogonal reagents–functional... 
DRUG | CELLS | 1,2,4-TRIAZINES | GENETIC-CODE | CYCLOPROPENE FATTY-ACIDS | CYCLOADDITIONS | CHEMISTRY | TETRAZINE LIGATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY
Journal Article
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 12/2017, Volume 23, Issue 72, pp. 18216 - 18224
Bioorthogonal reactions have emerged as a versatile tool in life sciences. The inverse electron demand Diels-Alder reaction (DA(inv)) stands out due to the... 
ACID-TEMPLATED REACTIONS | STAUDINGER REACTION | TRANS-CYCLOOCTENE | TETRAZINE LIGATION | CHEMISTRY, MULTIDISCIPLINARY | LIVE-CELL | proteins | IMPROVED STABILITY | DIELS-ALDER REACTION | dienophiles | LIVING SYSTEMS | FLUORESCENCE DETECTION | kinetics | tetrazine | DIRECTED TOSYL CHEMISTRY | rhodamine
Journal Article
BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, 02/2016, Volume 27, Issue 2, pp. 298 - 301
A first-of-its-kind F-18 pretargeted PET imaging approach based on the bioorthogonal inverse electron demand Diels-Alder (IEDDA) reaction between tetrazine... 
PEPTIDES | TETRAZINE | STRATEGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | CHEMISTRY, MULTIDISCIPLINARY | CA19.9
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 47, pp. 19119 - 19124
Journal Article
Journal of Photochemistry & Photobiology, A: Chemistry, ISSN 1010-6030, 04/2012, Volume 234, pp. 156 - 163
► New photochemistry by symmetric sulfur substitution of s-tetrazines. ► Stepwise photocleavage of cysteine S,S-tetrazine tracked by femtosecond IR. ► Peptide... 
Phototrigger | Phototolysis | Peptides | Infrared | Tetrazine | DIMETHYL-S-TETRAZINE | NONDENATURING ENVIRONMENT | HELIX NUCLEATION | CONFIGURATION-INTERACTION | CHEMISTRY, PHYSICAL | N-HETEROAROMATIC SYSTEMS | PHOTO-DISSOCIATION | UNIMOLECULAR TRIPLE DISSOCIATION | PICOSECOND CONFORMATIONAL TRANSITION | SYM-TETRAZINE | ELECTRONIC-STRUCTURE | Chemical properties
Journal Article
Chemical science, ISSN 2041-6520, 01/2016, Volume 7, Issue 1, pp. 799 - 802
Herein we present a significant step towards next-generation disulfide stapling reagents. A novel class of reagent has been designed to effect both disulfide... 
Journal Article
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