ACS APPLIED MATERIALS & INTERFACES, ISSN 1944-8244, 02/2019, Volume 11, Issue 7, pp. 7320 - 7329
The growing number of patient morbidity related to nosocomial infections has placed an importance on the development of new antibacterial coatings for medical...
URINARY-TRACT-INFECTION | nitric oxide | FILM | surface modification | MATERIALS SCIENCE, MULTIDISCIPLINARY | multidrug-resistant bacteria | ANTIMICROBIAL POLYMERS | NANOSCIENCE & NANOTECHNOLOGY | NO-DONOR PRODRUGS | DELIVERY | NANOPARTICLES | antimicrobial coating | polydopamine | THROMBORESISTANT | BIOFILM DISPERSAL | PSEUDOMONAS-AERUGINOSA | biofilm | SURFACE-CHEMISTRY | Biofilms - drug effects | Nitric Oxide - chemistry | Nitric Oxide - pharmacology | Staphylococcus aureus - physiology | Biofilms - growth & development | Coated Materials, Biocompatible - pharmacology | Coated Materials, Biocompatible - chemistry | Pseudomonas aeruginosa - physiology | Anti-Bacterial Agents - chemistry | Polymers - pharmacology | Indoles - pharmacology | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Indoles - chemistry
URINARY-TRACT-INFECTION | nitric oxide | FILM | surface modification | MATERIALS SCIENCE, MULTIDISCIPLINARY | multidrug-resistant bacteria | ANTIMICROBIAL POLYMERS | NANOSCIENCE & NANOTECHNOLOGY | NO-DONOR PRODRUGS | DELIVERY | NANOPARTICLES | antimicrobial coating | polydopamine | THROMBORESISTANT | BIOFILM DISPERSAL | PSEUDOMONAS-AERUGINOSA | biofilm | SURFACE-CHEMISTRY | Biofilms - drug effects | Nitric Oxide - chemistry | Nitric Oxide - pharmacology | Staphylococcus aureus - physiology | Biofilms - growth & development | Coated Materials, Biocompatible - pharmacology | Coated Materials, Biocompatible - chemistry | Pseudomonas aeruginosa - physiology | Anti-Bacterial Agents - chemistry | Polymers - pharmacology | Indoles - pharmacology | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Indoles - chemistry
Journal Article
Biomacromolecules, ISSN 1525-7797, 03/2005, Volume 6, Issue 2, pp. 780 - 789
A series of new nitric oxide (NO) releasing copolymers have been prepared by covalently anchoring alkyldiamine side chains onto a polymethacrylate-based...
BLOOD COMPATIBILITY | DESIGN | POLYMER SCIENCE | CHEMICAL SENSORS | THROMBORESISTANT | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY | CHEMISTRY, ORGANIC | PLATELET-ADHESION | Azo Compounds - chemistry | Nitric Oxide Donors - chemistry | Polymers - chemical synthesis | Coated Materials, Biocompatible - chemical synthesis | Diamines - chemistry | Polymers - chemistry | Kinetics | Nitric Oxide Donors - chemical synthesis | Polymethacrylic Acids - chemistry | Spectrum Analysis
BLOOD COMPATIBILITY | DESIGN | POLYMER SCIENCE | CHEMICAL SENSORS | THROMBORESISTANT | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY | CHEMISTRY, ORGANIC | PLATELET-ADHESION | Azo Compounds - chemistry | Nitric Oxide Donors - chemistry | Polymers - chemical synthesis | Coated Materials, Biocompatible - chemical synthesis | Diamines - chemistry | Polymers - chemistry | Kinetics | Nitric Oxide Donors - chemical synthesis | Polymethacrylic Acids - chemistry | Spectrum Analysis
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 03/2018, Volume 69, pp. 313 - 322
Small-caliber vascular grafts used in coronary artery bypass procedures typically fail due to the development of intimal hyperplasia or thrombosis. Our...
Sacrificial bonds | Thromboresistant coating | Hydrogel | Suture damage resistance | Vascular graft | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | Ethylene glycol | Coronary artery bypass | Hydrogen | Bonds | Polymerization | Transplantation of organs, tissues, etc | Air pollution | Biomedical engineering | sacrificial bonds | hydrogel | vascular graft | suture damage resistance | thromboresistant coating
Sacrificial bonds | Thromboresistant coating | Hydrogel | Suture damage resistance | Vascular graft | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | Ethylene glycol | Coronary artery bypass | Hydrogen | Bonds | Polymerization | Transplantation of organs, tissues, etc | Air pollution | Biomedical engineering | sacrificial bonds | hydrogel | vascular graft | suture damage resistance | thromboresistant coating
Journal Article
Journal of Bioactive and Compatible Polymers, ISSN 0883-9115, 7/2016, Volume 31, Issue 4, pp. 393 - 410
In this study, we developed a new approach in the preparation of chitosan-based polymeric nitric oxides. Chitosan film (unreacted chitosan) reacted with...
antimicrobial | nitric oxide | Chitosan | bacteria | biofilm | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | PARTICLES | SUBSTANCES | ANTIBACTERIAL AGENTS | FUNCTIONAL-GROUP | DENDRIMERS | RELEASE RATES | THROMBORESISTANT | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHEMISTRY | COATINGS | Biofilms | Antibiotics | Nitric oxide | Bacteria | Biocompatibility | Synergistic effect | Polymers
antimicrobial | nitric oxide | Chitosan | bacteria | biofilm | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | PARTICLES | SUBSTANCES | ANTIBACTERIAL AGENTS | FUNCTIONAL-GROUP | DENDRIMERS | RELEASE RATES | THROMBORESISTANT | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHEMISTRY | COATINGS | Biofilms | Antibiotics | Nitric oxide | Bacteria | Biocompatibility | Synergistic effect | Polymers
Journal Article
Analyst, ISSN 0003-2654, 2006, Volume 131, Issue 5, pp. 609 - 615
The continuous, real-time monitoring of clinically important analytes ( e. g., PO2, PCO2, pH, K+, Na+, glucose, and lactate) is of great importance to human...
CHEMISTRY, ANALYTICAL | CHEMICAL SENSORS | THROMBORESISTANT | BIOSENSORS | OXYGEN SENSORS | COATINGS | SOL-GELS | MICROARRAYS | BACTERIAL ADHESION | SENSING POLYMERIC FILMS | CATALYTIC GENERATION | Blood Chemical Analysis - methods | Delayed-Action Preparations - pharmacology | Humans | Biosensing Techniques | Monitoring, Physiologic - methods | Monitoring, Physiologic - instrumentation | Coated Materials, Biocompatible | Nitric Oxide | Bacterial Adhesion - drug effects | Blood Chemical Analysis - instrumentation | Platelet Adhesiveness - drug effects
CHEMISTRY, ANALYTICAL | CHEMICAL SENSORS | THROMBORESISTANT | BIOSENSORS | OXYGEN SENSORS | COATINGS | SOL-GELS | MICROARRAYS | BACTERIAL ADHESION | SENSING POLYMERIC FILMS | CATALYTIC GENERATION | Blood Chemical Analysis - methods | Delayed-Action Preparations - pharmacology | Humans | Biosensing Techniques | Monitoring, Physiologic - methods | Monitoring, Physiologic - instrumentation | Coated Materials, Biocompatible | Nitric Oxide | Bacterial Adhesion - drug effects | Blood Chemical Analysis - instrumentation | Platelet Adhesiveness - drug effects
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 06/2007, Volume 81A, Issue 4, pp. 956 - 963
Nitric oxide (NO) is released by endothelial cells that line the inner walls of healthy blood vessels at fluxes ranging from 0.5 Ă 10â10 to 4.0 Ă 10â10 mol...
nitric oxide | lactate dehydrogenase assay | plasticized poly(vinyl chloride) | bloodâcompatibility | platelet adhesion | Platelet adhesion | Blood-compatibility | Plasticized poly(vinyl chloride) | Lactate dehydrogenase assay | Nitric oxide | CONTROLLED BIOLOGICAL RELEASE | MATERIALS SCIENCE, BIOMATERIALS | CHEMICAL SENSORS | ENGINEERING, BIOMEDICAL | VIVO EVALUATION | DONORS | NUCLEOPHILES | THROMBORESISTANT | blood-compatibility | COATINGS | EXPRESSION | MODULATION | L-Lactate Dehydrogenase - metabolism | Rabbits | Microscopy, Electron, Scanning | Animals | Blood Platelets - ultrastructure | Surface Properties | Polymers - pharmacology | Blood Platelets - drug effects | Nitric Oxide - metabolism | Platelet Adhesiveness - drug effects
nitric oxide | lactate dehydrogenase assay | plasticized poly(vinyl chloride) | bloodâcompatibility | platelet adhesion | Platelet adhesion | Blood-compatibility | Plasticized poly(vinyl chloride) | Lactate dehydrogenase assay | Nitric oxide | CONTROLLED BIOLOGICAL RELEASE | MATERIALS SCIENCE, BIOMATERIALS | CHEMICAL SENSORS | ENGINEERING, BIOMEDICAL | VIVO EVALUATION | DONORS | NUCLEOPHILES | THROMBORESISTANT | blood-compatibility | COATINGS | EXPRESSION | MODULATION | L-Lactate Dehydrogenase - metabolism | Rabbits | Microscopy, Electron, Scanning | Animals | Blood Platelets - ultrastructure | Surface Properties | Polymers - pharmacology | Blood Platelets - drug effects | Nitric Oxide - metabolism | Platelet Adhesiveness - drug effects
Journal Article
Biomacromolecules, ISSN 1525-7797, 09/2006, Volume 7, Issue 9, pp. 2565 - 2574
A novel approach to potentially resolve serious thrombosis issues associated with kidney dialysis (hemodialysis) therapies is described. New water-soluble...
CELLS | POLYMERIC COATINGS | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | PLATELET-ADHESION | RELEASE | VASCULAR ENDOTHELIUM | THROMBORESISTANT | HIGH-RISK | IN-VIVO | CHEMISTRY | SOL-GELS | Nitric Oxide Donors - chemistry | Magnetic Resonance Spectroscopy | Models, Chemical | Nitric Oxide - chemistry | Humans | Renal Dialysis - methods | Renal Dialysis - instrumentation | Nitrites - chemistry | Spectroscopy, Fourier Transform Infrared | Equipment Design | Time Factors | Carboxylic Acids - chemistry | Polyethyleneimine - chemistry | Water - chemistry | Kinetics | Thrombosis - prevention & control | Thrombosis - therapy
CELLS | POLYMERIC COATINGS | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | PLATELET-ADHESION | RELEASE | VASCULAR ENDOTHELIUM | THROMBORESISTANT | HIGH-RISK | IN-VIVO | CHEMISTRY | SOL-GELS | Nitric Oxide Donors - chemistry | Magnetic Resonance Spectroscopy | Models, Chemical | Nitric Oxide - chemistry | Humans | Renal Dialysis - methods | Renal Dialysis - instrumentation | Nitrites - chemistry | Spectroscopy, Fourier Transform Infrared | Equipment Design | Time Factors | Carboxylic Acids - chemistry | Polyethyleneimine - chemistry | Water - chemistry | Kinetics | Thrombosis - prevention & control | Thrombosis - therapy
Journal Article
Journal of Materials Science: Materials in Medicine, ISSN 0957-4530, 1/2009, Volume 20, Issue 1, pp. 321 - 327
A monolayer and trilayer membrane configuration of ethylcellulose were doped with a new synthesized diazeniumdiolate GAGS/NO (glutaraldehyde modification of...
Polymer Sciences | Ceramics, Glass, Composites, Natural Methods | Characterization and Evaluation of Materials | Material Science | Metallic Materials | Surfaces and Interfaces, Thin Films | Biomaterials | POLYMERIC COATINGS | MATERIALS SCIENCE, BIOMATERIALS | THROMBORESISTANT | VASOSPASM | MECHANISM | EFFICACY | NITRIC-OXIDE RELEASE | ENGINEERING, BIOMEDICAL | KINETICS | PREVENTION | CHEMISTRY | SUBSTANCES | Nitric Oxide Donors - chemistry | Triazenes - chemistry | Biocompatible Materials - chemistry | Membranes, Artificial | Azo Compounds - chemical synthesis | Materials Testing | Spectroscopy, Fourier Transform Infrared | Glucosamine - chemistry | Spectrophotometry, Ultraviolet | Triazenes - chemical synthesis | Drug Carriers - chemistry | Azo Compounds - chemistry | Nitric Oxide Donors - administration & dosage | Cellulose - chemistry | Hydrophobic and Hydrophilic Interactions | Molecular Structure | Nitric Oxide Donors - chemical synthesis | Glutaral - chemistry | Delayed-Action Preparations | Azo Compounds - administration & dosage | Cellulose - analogs & derivatives | Crosslinked polymers | Analysis | Nitric oxide | Pharmacy | Materials science | Biomedical materials
Polymer Sciences | Ceramics, Glass, Composites, Natural Methods | Characterization and Evaluation of Materials | Material Science | Metallic Materials | Surfaces and Interfaces, Thin Films | Biomaterials | POLYMERIC COATINGS | MATERIALS SCIENCE, BIOMATERIALS | THROMBORESISTANT | VASOSPASM | MECHANISM | EFFICACY | NITRIC-OXIDE RELEASE | ENGINEERING, BIOMEDICAL | KINETICS | PREVENTION | CHEMISTRY | SUBSTANCES | Nitric Oxide Donors - chemistry | Triazenes - chemistry | Biocompatible Materials - chemistry | Membranes, Artificial | Azo Compounds - chemical synthesis | Materials Testing | Spectroscopy, Fourier Transform Infrared | Glucosamine - chemistry | Spectrophotometry, Ultraviolet | Triazenes - chemical synthesis | Drug Carriers - chemistry | Azo Compounds - chemistry | Nitric Oxide Donors - administration & dosage | Cellulose - chemistry | Hydrophobic and Hydrophilic Interactions | Molecular Structure | Nitric Oxide Donors - chemical synthesis | Glutaral - chemistry | Delayed-Action Preparations | Azo Compounds - administration & dosage | Cellulose - analogs & derivatives | Crosslinked polymers | Analysis | Nitric oxide | Pharmacy | Materials science | Biomedical materials
Journal Article
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Full Text
Use of the affinity chromatography principle in creating new thromboresistant materials
Journal of Chromatography B, ISSN 1570-0232, 2004, Volume 800, Issue 1, pp. 263 - 269
The principle of affinity chromatography was used for preparation of thromboresistant bilayer coatings. The outer biospecific layer containing Îľ-aminocaproic...
Bilayer coatings | Affinity chromatography principle | Plasminogen | Lysine | Thromboresistant materials | lysine | plasminogen | CHEMISTRY, ANALYTICAL | affinity chromatography principle | bilayer coatings | BIOCHEMICAL RESEARCH METHODS | thromboresistant materials | Cross-Linking Reagents | Fibrinolytic Agents - chemistry | Polyethylenes | Coated Materials, Biocompatible - chemistry | Maleates - chemistry | Povidone - analogs & derivatives | Povidone - chemistry | Albumins | Chromatography, Affinity | Chitin - analogs & derivatives | Plasminogen - chemistry | Blood Coagulation | Indicators and Reagents | Aminocaproic Acid - chemistry | Chitosan | Kinetics
Bilayer coatings | Affinity chromatography principle | Plasminogen | Lysine | Thromboresistant materials | lysine | plasminogen | CHEMISTRY, ANALYTICAL | affinity chromatography principle | bilayer coatings | BIOCHEMICAL RESEARCH METHODS | thromboresistant materials | Cross-Linking Reagents | Fibrinolytic Agents - chemistry | Polyethylenes | Coated Materials, Biocompatible - chemistry | Maleates - chemistry | Povidone - analogs & derivatives | Povidone - chemistry | Albumins | Chromatography, Affinity | Chitin - analogs & derivatives | Plasminogen - chemistry | Blood Coagulation | Indicators and Reagents | Aminocaproic Acid - chemistry | Chitosan | Kinetics
Journal Article
Journal of Applied Biomaterials and Functional Materials, ISSN 2280-8000, 2014, Volume 12, Issue 3, pp. 172 - 182
Localized nitric oxide (NO) release from polymeric materials holds much promise for the prevention of coagulation often associated with implantable and...
Mechanical properties | In situ diazeniumdiolation | Release kinetics | Polydimethylsiloxane | Nitric oxide | Polyurethane | POLYMERIC COATINGS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | PLATELET-ADHESION | MODEL | VASCULAR ENDOTHELIUM | ELASTOMERS | THROMBORESISTANT | INHIBITION | BIOPHYSICS | IN-VIVO EVALUATION | SECONDARY-AMINES | Biocompatible Materials - analysis | Nitric Oxide Donors - chemistry | Models, Chemical | Nitric Oxide - chemistry | Polyurethanes - chemistry | Biocompatible Materials - chemistry | Drug Implants - analysis | Materials Testing | Absorption, Physicochemical | Nitric Oxide - analysis | Drug Implants - chemistry | Computer Simulation | Dimethylpolysiloxanes - chemistry | Kinetics | Diffusion
Mechanical properties | In situ diazeniumdiolation | Release kinetics | Polydimethylsiloxane | Nitric oxide | Polyurethane | POLYMERIC COATINGS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | PLATELET-ADHESION | MODEL | VASCULAR ENDOTHELIUM | ELASTOMERS | THROMBORESISTANT | INHIBITION | BIOPHYSICS | IN-VIVO EVALUATION | SECONDARY-AMINES | Biocompatible Materials - analysis | Nitric Oxide Donors - chemistry | Models, Chemical | Nitric Oxide - chemistry | Polyurethanes - chemistry | Biocompatible Materials - chemistry | Drug Implants - analysis | Materials Testing | Absorption, Physicochemical | Nitric Oxide - analysis | Drug Implants - chemistry | Computer Simulation | Dimethylpolysiloxanes - chemistry | Kinetics | Diffusion
Journal Article
Macromolecular Bioscience, ISSN 1616-5187, 09/2019, Volume 19, Issue 9, pp. e1900154 - n/a
A facile approach to enhancing the blood compatibility of solid surfaces based on ZrIVâheparin complexation is reported. Solid surfaces are pretreated with...
heparin | coordination bond | tannic acid | zirconium(IV) | antiplatelet application | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TERM | ADSORPTION | INSPIRED ADHESIVE HEPARIN | THROMBORESISTANT | Zirconium | Crosslinked polymers | Heparin | Tannic acid | Multilayers | Solid surfaces | Metals | Immobilization | Oxides | Crosslinking | Polymers | Substrates
heparin | coordination bond | tannic acid | zirconium(IV) | antiplatelet application | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TERM | ADSORPTION | INSPIRED ADHESIVE HEPARIN | THROMBORESISTANT | Zirconium | Crosslinked polymers | Heparin | Tannic acid | Multilayers | Solid surfaces | Metals | Immobilization | Oxides | Crosslinking | Polymers | Substrates
Journal Article
Chemistry of Materials, ISSN 0897-4756, 11/2003, Volume 15, Issue 22, pp. 4193 - 4199
Nitric oxide (NO)-releasing solâgel materials are synthesized by combining amine-functionalized alkoxysilanes (aminosilanes) with alkyltrimethoxysilanes...
CHEMICAL SENSORS | THROMBORESISTANT | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | BIOLOGICAL RESPONSES | PLATELET-ADHESION | RELEASE | IN-VIVO EVALUATION | POLYMERIC FILMS | BIOFILM FORMATION | SURFACES
CHEMICAL SENSORS | THROMBORESISTANT | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | BIOLOGICAL RESPONSES | PLATELET-ADHESION | RELEASE | IN-VIVO EVALUATION | POLYMERIC FILMS | BIOFILM FORMATION | SURFACES
Journal Article
Journal of Applied Polymer Science, ISSN 0021-8995, 11/2011, Volume 122, Issue 3, pp. 1712 - 1721
Nitric oxide (NO) is a well known potent antiplatelet agent, and its continuous release will effectively prevent the adhesion of platelets on artificial blood...
lipophilic Cu(II)âcomplex | hemocompatibility | NO generation | polycarbonateurethanes | lipophilic Cu(II)-complex | POLYMER SCIENCE | METAL-ION | NETWORKS | PLATELET-ADHESION | IMPROVED HEMOCOMPATIBILITY | RELEASE | POLYMERIC FILMS | POLYURETHANES | THROMBORESISTANT | S-NITROSOTHIOLS | SURFACE | Surgical implants | Ascorbic acid | Flux | Nanomaterials | In vitro testing | Nanostructure | POLYCARBONATES | MICROSTRUCTURES | Blending | TENSILE STRENGTH | MECHANICAL PROPERTIES | OXIDES | FLUXES | CATALYSTS | BLOOD
lipophilic Cu(II)âcomplex | hemocompatibility | NO generation | polycarbonateurethanes | lipophilic Cu(II)-complex | POLYMER SCIENCE | METAL-ION | NETWORKS | PLATELET-ADHESION | IMPROVED HEMOCOMPATIBILITY | RELEASE | POLYMERIC FILMS | POLYURETHANES | THROMBORESISTANT | S-NITROSOTHIOLS | SURFACE | Surgical implants | Ascorbic acid | Flux | Nanomaterials | In vitro testing | Nanostructure | POLYCARBONATES | MICROSTRUCTURES | Blending | TENSILE STRENGTH | MECHANICAL PROPERTIES | OXIDES | FLUXES | CATALYSTS | BLOOD
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2004, Volume 37, Issue 7, pp. 926 - 936
The synthetic methods used recently in this laboratory to prepare a variety of novel nitric oxide (NO)-releasing hydrophobic polymers are reviewed. Nitric...
Diazeniumdiolates | Nitrosothiols | Free radicals | Nitric oxide | Biocompatibility | Thromboresistant | Polymers | Controlled release | nitric oxide | free radicals | CONTROLLED BIOLOGICAL RELEASE | CHEMICAL SENSORS | DIETHYLAMINE | diazeniumdiolates | biocompatibility | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXING FACTOR | NITROGEN(II) OXIDE | IDENTIFICATION | AQUEOUS-SOLUTION | nitrosothiols | controlled release | ENDOTHELIUM | ENDOCRINOLOGY & METABOLISM | polymers | IN-VIVO EVALUATION | thromboresistant | Animals | Nitric Oxide Donors - chemistry | Blood Vessels - metabolism | Humans | Blood Vessels - drug effects | Polymers - pharmacology | Hydrophobic and Hydrophilic Interactions | Polymers - chemistry | Nitric Oxide Donors - pharmacology | Nitric Oxide - metabolism
Diazeniumdiolates | Nitrosothiols | Free radicals | Nitric oxide | Biocompatibility | Thromboresistant | Polymers | Controlled release | nitric oxide | free radicals | CONTROLLED BIOLOGICAL RELEASE | CHEMICAL SENSORS | DIETHYLAMINE | diazeniumdiolates | biocompatibility | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXING FACTOR | NITROGEN(II) OXIDE | IDENTIFICATION | AQUEOUS-SOLUTION | nitrosothiols | controlled release | ENDOTHELIUM | ENDOCRINOLOGY & METABOLISM | polymers | IN-VIVO EVALUATION | thromboresistant | Animals | Nitric Oxide Donors - chemistry | Blood Vessels - metabolism | Humans | Blood Vessels - drug effects | Polymers - pharmacology | Hydrophobic and Hydrophilic Interactions | Polymers - chemistry | Nitric Oxide Donors - pharmacology | Nitric Oxide - metabolism
Journal Article
Thrombosis Research, ISSN 0049-3848, 1986, Volume 44, Issue 6, pp. 739 - 748
About 8000 Daltons porcine mucosa heparin fragments were covalently bonded by end-point attachment to polyethylene. The interaction between the immobilized...
heparin | Thromboresistant surface | antithrombin III | thrombin | biomaterial | immobilized heparin | Drug Synergism | Biocompatible Materials - metabolism | Time Factors | Humans | Surface Properties | Thrombin - antagonists & inhibitors | Antithrombin III - metabolism | Protein Binding | Polyethylenes - pharmacology | Structure-Activity Relationship | Thrombin - metabolism | Heparin - pharmacology
heparin | Thromboresistant surface | antithrombin III | thrombin | biomaterial | immobilized heparin | Drug Synergism | Biocompatible Materials - metabolism | Time Factors | Humans | Surface Properties | Thrombin - antagonists & inhibitors | Antithrombin III - metabolism | Protein Binding | Polyethylenes - pharmacology | Structure-Activity Relationship | Thrombin - metabolism | Heparin - pharmacology
Journal Article
ACS Applied Materials & Interfaces, ISSN 1944-8244, 03/2014, Volume 6, Issue 6, pp. 3779 - 3783
A controllable and inexpensive electrochemical nitric oxide (NO) release system is demonstrated to improve hemocompatibility and reduce bacterial biofilm...
thromboresistant catheters | modulated NO release | nitric oxide | electrochemical reduction of nitrite | antimicrobial catheters | anti-biofilm | COPPER-COMPLEXES | ACTIVATION | MATERIALS SCIENCE, MULTIDISCIPLINARY | PLATELET | REACTIVITY | NANOSCIENCE & NANOTECHNOLOGY | MODEL | SILICONE-RUBBER | GENERATION | BINDING | Rabbits | Nitric Oxide - chemistry | Nitric Oxide - pharmacology | Pyridines - chemistry | Humans | Bacteria - drug effects | Nitrites - chemistry | Catheter-Related Infections - prevention & control | Animals | Copper - chemistry | Catheter-Related Infections - microbiology | Vascular Access Devices - microbiology | Organometallic Compounds - chemistry | Letter
thromboresistant catheters | modulated NO release | nitric oxide | electrochemical reduction of nitrite | antimicrobial catheters | anti-biofilm | COPPER-COMPLEXES | ACTIVATION | MATERIALS SCIENCE, MULTIDISCIPLINARY | PLATELET | REACTIVITY | NANOSCIENCE & NANOTECHNOLOGY | MODEL | SILICONE-RUBBER | GENERATION | BINDING | Rabbits | Nitric Oxide - chemistry | Nitric Oxide - pharmacology | Pyridines - chemistry | Humans | Bacteria - drug effects | Nitrites - chemistry | Catheter-Related Infections - prevention & control | Animals | Copper - chemistry | Catheter-Related Infections - microbiology | Vascular Access Devices - microbiology | Organometallic Compounds - chemistry | Letter
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 33, pp. 8450 - 8458
Abstract The regulatory role of nitric oxide (NO) in cell signaling has been well recognized. Clinically, NO deficiency is known to be associated with severe...
Advanced Basic Science | Dentistry | β-galactosidase | Chitosan | Nitric oxide | Cardiovascular biomaterials | Controlled release | PROGENITOR CELLS | POLYMERS | VASCULAR GRAFTS | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | GROWTH-FACTOR DELIVERY | POTENTIAL APPLICATION | beta-galactosidase | ENGINEERING, BIOMEDICAL | CLICK CHEMISTRY | CELL-PROLIFERATION | THROMBORESISTANT | INSIGHTS | Nitric Oxide - chemistry | Click Chemistry | Nitric Oxide - pharmacology | Biocompatible Materials - chemistry | Humans | Cells, Cultured | Nitric Oxide - therapeutic use | Diabetes Mellitus, Type 1 - drug therapy | Platelet Adhesiveness - drug effects | Animals | Chitosan - chemistry | Polysaccharides - chemistry | Cell Proliferation - drug effects | Mice | Enzymes | Medical colleges | Polysaccharides | Biological products | Medical examination | Physiological aspects | Development and progression | Catalysis | Diabetes | Galactose | Blood
Advanced Basic Science | Dentistry | β-galactosidase | Chitosan | Nitric oxide | Cardiovascular biomaterials | Controlled release | PROGENITOR CELLS | POLYMERS | VASCULAR GRAFTS | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | GROWTH-FACTOR DELIVERY | POTENTIAL APPLICATION | beta-galactosidase | ENGINEERING, BIOMEDICAL | CLICK CHEMISTRY | CELL-PROLIFERATION | THROMBORESISTANT | INSIGHTS | Nitric Oxide - chemistry | Click Chemistry | Nitric Oxide - pharmacology | Biocompatible Materials - chemistry | Humans | Cells, Cultured | Nitric Oxide - therapeutic use | Diabetes Mellitus, Type 1 - drug therapy | Platelet Adhesiveness - drug effects | Animals | Chitosan - chemistry | Polysaccharides - chemistry | Cell Proliferation - drug effects | Mice | Enzymes | Medical colleges | Polysaccharides | Biological products | Medical examination | Physiological aspects | Development and progression | Catalysis | Diabetes | Galactose | Blood
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 01/2019, Volume 84, pp. 77 - 87
A dual functional polyurethane (PU) film that mimics aspects of blood vessel inner surfaces by combining surface texturing and nitric oxide (NO) release was...
Surface texturing | Nitric oxide release | Anticoagulation | Biomimetic | Antibacteria | POLYMERS | MATERIALS SCIENCE, BIOMATERIALS | WETTABILITY | MECHANISM | ENGINEERING, BIOMEDICAL | PLATELET-ADHESION | CONTACT ACTIVATION | PROTEIN-ADSORPTION | THROMBORESISTANT | INHIBITION | FACTOR XII | BIOMEDICAL APPLICATIONS | Medical equipment | Blood coagulation | Adhesion tests | Coagulation | Activation | Infections | Blood | Biomaterials | Fabrication | Biomedical materials | Microorganisms | Biomimetics | Medical electronics | Biocompatibility | Bacteria | Pseudomonas aeruginosa | Thromboembolism | Polyurethane resins | Medical devices | Blood vessels | Risk reduction | Thrombosis | Adhesion | Coagulation factors | Nitric oxide | Polyurethane | Texturing | Synergistic effect | Platelets | Coagulation factor XII
Surface texturing | Nitric oxide release | Anticoagulation | Biomimetic | Antibacteria | POLYMERS | MATERIALS SCIENCE, BIOMATERIALS | WETTABILITY | MECHANISM | ENGINEERING, BIOMEDICAL | PLATELET-ADHESION | CONTACT ACTIVATION | PROTEIN-ADSORPTION | THROMBORESISTANT | INHIBITION | FACTOR XII | BIOMEDICAL APPLICATIONS | Medical equipment | Blood coagulation | Adhesion tests | Coagulation | Activation | Infections | Blood | Biomaterials | Fabrication | Biomedical materials | Microorganisms | Biomimetics | Medical electronics | Biocompatibility | Bacteria | Pseudomonas aeruginosa | Thromboembolism | Polyurethane resins | Medical devices | Blood vessels | Risk reduction | Thrombosis | Adhesion | Coagulation factors | Nitric oxide | Polyurethane | Texturing | Synergistic effect | Platelets | Coagulation factor XII
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 11/2013, Volume 101, Issue 11, pp. 3201 - 3210
One mechanism of the failure of bloodâcontacting devices is clotting. Nitric oxide (NO) releasing materials are seen as a viable s