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International Journal of COPD, ISSN 1176-9106, 02/2015, Volume 10, pp. 239 - 259
Journal Article
Journal Article
International Journal of COPD, ISSN 1176-9106, 10/2014, Volume 9, pp. 1133 - 1144
Background: Combining bronchodilators with different mechanisms of action may improve efficacy and reduce risk of side effects compared to increasing the dose... 
Olodaterol Respimat | Long-acting muscarinic antagonist | Bronchodilator | Long-acting beta2-agonist | Tiotropium HandiHaler | INDACATEROL | TRIALS | OBSTRUCTIVE PULMONARY-DISEASE | MANAGEMENT | long-acting beta2-agonist | RESPIRATORY SYSTEM | tiotropium HandiHaler (R) | long-acting muscarinic antagonist | bronchodilator | olodaterol Respimat (R) | Spirometry | Bronchodilator Agents - administration & dosage | United States | Humans | Middle Aged | Muscarinic Antagonists - adverse effects | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Equipment Design | Forced Expiratory Volume | Time Factors | Adrenergic beta-2 Receptor Agonists - adverse effects | Scopolamine Derivatives - administration & dosage | Female | Surveys and Questionnaires | Bronchodilator Agents - adverse effects | Drug Therapy, Combination | Scopolamine Derivatives - adverse effects | Tiotropium Bromide | Pulmonary Disease, Chronic Obstructive - diagnosis | Benzoxazines - administration & dosage | Double-Blind Method | Drug Administration Schedule | Administration, Inhalation | Benzoxazines - adverse effects | Treatment Outcome | Lung - physiopathology | Muscarinic Antagonists - administration & dosage | Lung - drug effects | Adrenergic beta-2 Receptor Agonists - administration & dosage | Aged | Nebulizers and Vaporizers | Pulmonary Disease, Chronic Obstructive - drug therapy | Tiotropium | Lung diseases, Obstructive | Research | Drug therapy, Combination | Drug therapy | Health aspects
Journal Article
RESPIRATORY MEDICINE, ISSN 0954-6111, 01/2009, Volume 103, Issue 1, pp. 22 - 29
Background: Tiotropium, a once daily inhaled anticholinergic delivered via HandiHaler (R), provides bronchodilation for >24 h and improves patient-centred... 
CARDIAC & CARDIOVASCULAR SYSTEMS | Inhalation therapy | SAFETY | PERFORMANCE | LUNG-FUNCTION | EXERCISE TOLERANCE | Respimat (R) | COMBINATION | SALMETEROL | ONCE-DAILY TIOTROPIUM | Anticholinergics | Tiotropium | OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | Bronchodilators | Chronic obstructive pulmonary disease | FLUTICASONE | HEALTH OUTCOMES
Journal Article
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ISSN 1178-2005, 2016, Volume 11, pp. 2859 - 2867
Purpose: To compare the bronchodilator efficacy of 18 mu g once-daily tiotropium inhalation administered via Discair (R) versus HandiHaler (R) in adults with... 
MANAGEMENT | non-inferiority | Discair (R) | INHALER DEVICES | ADHERENCE | tiotropium | bronchodilator efficacy | IMPACT | spirometry | HandiHaler (R) | RESPIRATORY SYSTEM | ASTHMA | PATIENT | POWDER | COPD PATIENTS | RESPIMAT | HEALTH OUTCOMES
Journal Article
Journal Article
International Journal of COPD, ISSN 1176-9106, 10/2013, Volume 8, pp. 483 - 492
Purpose: The long-acting inhaled anticholinergic agent, tiotropium, is recommended as first-line maintenance therapy for moderate to very severe Chronic... 
HandiHaler | Health-related quality of life | Tiotropium | Chronic obstructive pulmonary disease | TRIAL | OBSTRUCTIVE PULMONARY-DISEASE | PRIMARY-CARE | HandiHaler (R) | EFFICACY | RESPIRATORY SYSTEM | health-related quality of life | QUALITY-OF-LIFE | tiotropium | chronic obstructive pulmonary disease | HEALTH-STATUS | COPD | Bronchodilator Agents - therapeutic use | Europe, Eastern | Multivariate Analysis | Predictive Value of Tests | Prospective Studies | Age Factors | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Recovery of Function | Time Factors | Scopolamine Derivatives - administration & dosage | Product Surveillance, Postmarketing | Female | Surveys and Questionnaires | Scopolamine Derivatives - therapeutic use | Cholinergic Antagonists - therapeutic use | Tiotropium Bromide | Severity of Illness Index | Pulmonary Disease, Chronic Obstructive - diagnosis | Drug Administration Schedule | Risk Factors | Administration, Inhalation | Treatment Outcome | Lung - physiopathology | Cholinergic Antagonists - administration & dosage | Medication Adherence | Lung - drug effects | Aged | Health Status | Nebulizers and Vaporizers | Pulmonary Disease, Chronic Obstructive - drug therapy | Medicine | Lung diseases, Obstructive | Analysis | Practice | Respiratory agents | Drug therapy | Health aspects | Quality management | Original Research
Journal Article
RESPIRATORY MEDICINE, ISSN 0954-6111, 02/2010, Volume 104, Issue 2, pp. 228 - 236
Background and objectives: To compare the efficacy and safety of tiotropium inhaled via Respimat(R) Soft Mist Inhaler, a multidose propellant-free inhaler and... 
BRONCHODILATOR | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | PERFORMANCE | EXERCISE TOLERANCE | SOFT MIST(TM) INHALER | TRIAL | Tiotropium | OBSTRUCTIVE PULMONARY-DISEASE | IPRATROPIUM | RESPIRATORY SYSTEM | Bronchodilators | EXACERBATIONS | Inhalation devices | Pharmacokinetics | COPD | HEALTH OUTCOMES
Journal Article
COPD: Journal of Chronic Obstructive Pulmonary Disease, ISSN 1541-2555, 09/2018, Volume 15, Issue 5, pp. 418 - 423
The effectiveness of the tiotropium Respimat ® formulation in routine clinical practice is still an open issue due to concern about the generalizability of the... 
Tiotropium | HandiHaler | cohort study | chronic obstructive pulmonary disease (COPD) | comparative effectiveness | Respimat | real-world data | RESPIRATORY SYSTEM | INCLUSION | INHALER
Journal Article