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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2009, Volume 119, Issue 4, pp. 772 - 787
Idiopathic pulmonary fibrosis (IPF) is characterized by distorted lung architecture and loss of respiratory function. Enhanced (myo)fibroblast activation, ECM... 
EPITHELIAL-MESENCHYMAL TRANSITION | PATHOGENESIS | MEDICINE, RESEARCH & EXPERIMENTAL | LUNG FIBROSIS | CELLS | APOPTOSIS | TISSUE GROWTH-FACTOR | CCN FAMILY | MECHANISMS | EXPRESSION | INTERSTITIAL PNEUMONIAS | Oncogene Proteins - genetics | Up-Regulation | Idiopathic Pulmonary Fibrosis - genetics | Epithelial Cells - metabolism | Humans | Middle Aged | Male | Pulmonary Fibrosis - genetics | Wnt Proteins - metabolism | Oncogene Proteins - physiology | CCN Intercellular Signaling Proteins | Idiopathic Pulmonary Fibrosis - etiology | Pulmonary Alveoli - metabolism | Adult | Female | Intracellular Signaling Peptides and Proteins - genetics | Pulmonary Fibrosis - etiology | Bleomycin - toxicity | Disease Models, Animal | Pulmonary Alveoli - pathology | Mice, Inbred C57BL | Oncogene Proteins - pharmacology | Epithelial Cells - pathology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Recombinant Proteins - pharmacology | beta Catenin - metabolism | Animals | Models, Biological | Proto-Oncogene Proteins - physiology | Pulmonary Fibrosis - physiopathology | Cell Proliferation - drug effects | Idiopathic Pulmonary Fibrosis - physiopathology | Mice | Intracellular Signaling Peptides and Proteins - physiology | Cellular proteins | Pulmonary fibrosis | Genes | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e41394 - e41394
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2013, Volume 1832, Issue 7, pp. 884 - 890
Mechanical forces are essential to the development and progression of fibrosis, and are likely to be as important as soluble factors. These forces regulate the... 
Stretch | Tissue stiffness | Tension | Shear | Myofibroblast | Hydrostatic pressure | CAPILLARY MORPHOGENESIS | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERSTITIAL FLOW | NONLINEAR ELASTICITY | GROWTH-FACTOR-BETA | FIBROBLAST TRACTION | HEPATIC STELLATE CELLS | BIOPHYSICS | SHEAR-STRESS | LATENT TGF-BETA-1 | EXTRACELLULAR-MATRIX | Myofibroblasts | Humans | Disease Progression | Fibrosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 35, pp. 13051 - 13056
Idiopathic interstitial pneumonias (IIPs) have a progressive and often fatal course, and their enigmatic etiology has complicated approaches to effective... 
Telomeres | Pulmonary alveoli | Lungs | Interstitial lung diseases | Idiopathic pulmonary fibrosis | Liver | Fibrosis | Dyskeratosis congenita | Genetic mutation | Liver cirrhosis | Liver fibrosis | Interstitial lung disease | Telomerase | Aplastic anemia | RNA | MULTIDISCIPLINARY SCIENCES | DOMINANT DYSKERATOSIS-CONGENITA | REVERSE-TRANSCRIPTASE | LENGTH | IN-SITU HYBRIDIZATION | TERMINAL TRANSFERASE | liver fibrosis | dyskeratosis congenita | telomerase | GENE | interstitial lung disease | FAMILIES | aplastic anemia | MUTATIONS | APLASTIC-ANEMIA | Biomarkers - metabolism | Leukocytes, Mononuclear - metabolism | Epithelium - pathology | Pulmonary Alveoli - pathology | Pulmonary Fibrosis - complications | Fibrosis - complications | Humans | Risk Factors | In Situ Hybridization, Fluorescence | Tomography, X-Ray Computed | Pulmonary Fibrosis - genetics | Pulmonary Fibrosis - pathology | Case-Control Studies | RNA - genetics | Fibrosis - diagnostic imaging | Telomerase - genetics | Pulmonary Fibrosis - diagnostic imaging | Germ-Line Mutation | Family | Heterozygote | Telomere - metabolism | Fibrosis - pathology | Genetic aspects | Pulmonary fibrosis | Properties | Health aspects | Risk factors | Tissue | Leucocytes | Pneumonia | Mutation | Chromosomes | Deoxyribonucleic acid--DNA | Epithelial cells | Lung | Lung diseases | Heredity | Leukocytes | Cirrhosis | Etiology | telomerase reverse transcriptase | Alveoli | Age | Index Medicus | Biological Sciences
Journal Article