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EuPA Open Proteomics, ISSN 2212-9685, 09/2015, Volume 8, Issue C, pp. 40 - 47
Enabling the implementation of top down proteomic techniques within clinical workflows requires a dramatic increase in sensitivity. It has been previously... 
Top down | Protein oxidation | Electrospray ionization | Proteoforms
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2016, Volume 6
We have designed a versatile and sensitive liquid chromatographic (LC) system, featuring a monolithic trap column and a very narrow (10 mu m ID) fused silica... 
NANO-LC | OPEN-TUBULAR COLUMNS | TOP-DOWN PROTEOMICS | MULTIDISCIPLINARY SCIENCES | ANTIBODY | OPTIMIZATION | TIME | IONIZATION | EFFICIENCY | ONLINE
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 02/2015, Volume 1381, pp. 1 - 12
The purpose of clinical proteomics is to characterise protein profiles of a plethora of diseases with the aim of finding specific biomarkers. These are... 
Peptide separation | Mass spectrometry | Protein | Proteomics | CHEMISTRY, ANALYTICAL | QUANTITATIVE PROTEOMICS | HUMAN PLASMA | BIOCHEMICAL RESEARCH METHODS | IDENTIFICATION | IDENTIFY PROTEINS | TOP-DOWN | BIOMARKER DISCOVERY | ENZYMATIC DIGESTION | RNA DEGRADOSOME COMPOSITION | LABEL | BOTTOM-UP | Proteins | Liquid chromatography | Cells | Fractionation | Separation | Peptides | Strategy | Complexity
Journal Article
Journal Article
by Sun, RX and Luo, L and Chi, H and Liu, C and He, SM
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, ISSN 1000-3282, 02/2015, Volume 42, Issue 2, pp. 101 - 114
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1558, pp. 381 - 394
Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids... 
Intact protein | Top-down | Bioinformatics | Mass spectrometry | Proteomics | ProSight lite | ProSight Lite
Journal Article