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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 26, pp. 10777 - 10782
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2015, Volume 48, Issue 1, pp. 74 - 78
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1121 - 8
Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria... 
SYSTEM | ENTRY | MECHANISM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DOXORUBICIN | TUMOR | VALIDATION | MICROSCOPY | BINDING | DELIVERY | Receptors, Virus - metabolism | Humans | Arenaviruses, New World - genetics | Arenaviruses, New World - metabolism | Plasmodium vivax - genetics | Substrate Specificity | Hemochromatosis Protein - chemistry | Receptors, Virus - genetics | Protozoan Proteins - genetics | Antigens, CD - genetics | Transferrin - genetics | Apoferritins - metabolism | Antigens, CD - metabolism | Protozoan Proteins - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Viral Envelope Proteins - metabolism | Protozoan Proteins - chemistry | Antigens, CD - chemistry | Protein Interaction Domains and Motifs | Receptors, Transferrin - genetics | Binding Sites | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Plasmodium vivax - metabolism | Viral Envelope Proteins - genetics | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Recombinant Proteins - chemistry | Apoferritins - chemistry | Apoferritins - genetics | Hemochromatosis Protein - metabolism | Recombinant Proteins - genetics | Receptors, Transferrin - metabolism | Cryoelectron Microscopy | Receptors, Virus - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Hemochromatosis Protein - genetics | Viral Envelope Proteins - chemistry | Transferrin - chemistry | Protein Binding | HeLa Cells | Transferrin - metabolism | Receptors, Transferrin - chemistry | Binding | Vector-borne diseases | Transferrin | Endocytosis | Malaria | Ferritin | Iron | Epitopes | Electron microscopy | Cellular structure | Mimicry
Journal Article
Journal Article
Science (New York, N.Y.), ISSN 0036-8075, 01/2018, Volume 359, Issue 6371, p. 48
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 11/2019, Volume 23, Issue 11, pp. 7349 - 7359
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7567, pp. 124 - 128
Mitochondria are involved in a variety of cellular functions, including ATP production, amino acid and lipid biogenesis and breakdown, signalling and... 
APOPTOSIS | MUTANTS | ACID | MITOFUSIN 2 | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | DYSFUNCTION | STRESS | DROSOPHILA | PARKINSONS-DISEASE | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Antigens, CD - metabolism | Stearic Acids - metabolism | Drosophila melanogaster - metabolism | Ubiquitination - drug effects | Acetyltransferases - deficiency | Mitochondria - genetics | Larva - drug effects | Larva - genetics | Membrane Proteins - metabolism | Stearic Acids - administration & dosage | Larva - metabolism | Drosophila melanogaster - cytology | Ubiquitin-Protein Ligases - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Receptors, Transferrin - metabolism | Drosophila melanogaster - drug effects | Animals | Mitochondrial Dynamics - drug effects | Diet | Signal Transduction - drug effects | Drosophila Proteins - deficiency | Ubiquitin-Protein Ligases - deficiency | Drosophila Proteins - genetics | HeLa Cells | Ubiquitin-Protein Ligases - genetics | Stearic Acids - pharmacology | Tumor Suppressor Proteins | Mitochondria | Cell receptors | Genetic aspects | Stearic acid | Genetic regulation | Health aspects | Proteins | Insects | Acids | Morphology | Parkinsons disease | Pink | Parkinsons | Drosophila | mitochondria | metabolism | mitofusin | Parkin
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 381, Issue 2, pp. 331 - 340
Highlights • EGFR interacts with TfR1 in a kinase-dependent manner. • EGFR kinase activity maintains cell surface TfR1 expression. • EGFR kinase activity... 
Hematology, Oncology and Palliative Medicine | Iron homeostasis | Tyrosine phosphorylation | TfR1 | EGFR | METABOLISM | ONCOLOGY | CELL-CYCLE | ENDOCYTOSIS | EXPRESSION | MOLECULAR-MECHANISMS | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | ErbB Receptors - genetics | Homeostasis | Lung Neoplasms - pathology | Antigens, CD - genetics | Antigens, CD - metabolism | Transfection | Time Factors | Female | Adenocarcinoma - genetics | Receptors, Transferrin - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | A549 Cells | Cytoplasm - enzymology | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Lung Neoplasms - enzymology | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - enzymology | Adenocarcinoma - drug therapy | Iron - metabolism | Receptors, Transferrin - metabolism | Xenograft Model Antitumor Assays | Cell Cycle Checkpoints | Animals | Mice, Nude | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Apoptosis | Lung cancer, Non-small cell | Transferrin | Immunoglobulins | Lung cancer | Kinases | Metabolism | Studies | Proteins | Cell growth | Epidermal growth factor | Rodents | Cell cycle | Mutation | Deoxyribonucleic acid--DNA
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1518 - 13
Transferrin receptor 1 (TFR1) is a transmembrane glycoprotein that allows for transferrin-bound iron uptake in mammalian cells. It is overexpressed in various... 
APOPTOSIS | HYPERMETHYLATION | IRON HOMEOSTASIS | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | GROWTH | C-MYC | GENE-EXPRESSION | CELL-CYCLE | PROLIFERATION | MICRORNA | Cell proliferation | Post-transcription | Liver cancer | Cell growth | Transferrin | 3' Untranslated regions | Gene regulation | MiRNA | Hepatocellular carcinoma | Iron | Regulatory sequences | Mammalian cells
Journal Article