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1. Full Text NIEHS: Making a mark on translational research science
by Collman, Gwen W and Berridge, Brian R and Hall, Janet E and Woychik, Rick and Zeldin, Darryl C and Birnbaum, Linda S
Environmental Health Perspectives, ISSN 0091-6765, 08/2018, Volume 126, Issue 8, pp. 081001 - 081001
ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | National Institute of Environmental Health Sciences (U.S.) | Environmental Health - statistics & numerical data | Translational Medical Research - statistics & numerical data | United States | Humans | Medicine, Experimental | Services | Medical research | Environmental health | Index Medicus
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2. Full Text Hypoxia protects the liver from Small For Size Syndrome: A lesson learned from the associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure in rats
by Dili, Alexandra and Bertrand, Claude and Lebrun, Valérie and Pirlot, Boris and Leclercq, Isabelle A
American Journal of Transplantation, ISSN 1600-6135, 2019
Portal hyperperfusion and "dearterialization" of the liver remnant are the main pathogenic mechanisms for Small For Size syndrome (SFSS). Associating liver... 
animal models | translational research/science | liver disease | disease pathogenesis | liver transplantation/hepatology | basic (laboratory) research/science
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3. Full Text The Knife’s Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques
by Zheng, H.B and Watkins, B and Tkachev, V and Yu, S and Tran, D and Furlan, S and Zeleski, K and Singh, K and Hamby, K and Hotchkiss, C and Lane, J and Gumber, S and Adams, A.B and Cendales, L and Kirk, A.D and Kaur, A and Blazar, B.R and Larsen, C.P and Kean, L.S
American Journal of Transplantation, ISSN 1600-6135, 03/2017, Volume 17, Issue 3, pp. 657 - 670
While stable mixed-hematopoietic chimerism induces robust immune tolerance to solid organ allografts in mice, the translation of this strategy to large animal... 
bone marrow/hematopoietic stem cell transplantation | translational research/science | animal models: nonhuman primate | tolerance: chimerism
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4. Full Text Reengineering Clinical Research Science
: A Focus on Translational Research
by Ferrell, Courtney B
Behavior Modification, ISSN 0145-4455, 01/2009, Volume 33, Issue 1, pp. 7 - 23
The burden of disease in the United States is high. Mental illness is currently the leading cause of disease burden among 15- to 44-year-olds. This phenomenon... 
NIH | Clinical research | Translational research | clinical research | translational research | HEALTH | PSYCHOLOGY, CLINICAL | DISCOVERY | NIH ROADMAP | Neurological Impairments | Public Health | Mental Disorders | Neurological Organization | Chronic Illness | Genetics | Research Needs | Research Methodology | Behavioral Science Research | Scientific Research | Diseases | Mental Disorders - therapy | United States | Humans | Cost of Illness | Biological Science Disciplines - methods | Research Support as Topic | National Institutes of Health (U.S.) | Clinical Medicine | National Institute of Mental Health (U.S.) | Communication Barriers | Biomedical Research - education | Diffusion of Innovation | Biomedical Research - methods | Mental disorders | Health risk assessment | Neurosciences | Initiatives | Medical research | Human Genome Project | Medical treatment | Index Medicus
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5. Full Text The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell–mediated rejection, antibody‐mediated rejection, and prospects for integrative endpoints for next‐generation clinical trials
by Haas, M and Loupy, A and Lefaucheur, C and Roufosse, C and Glotz, D and Seron, D and Nankivell, B. J and Halloran, P. F and Colvin, R. B and Akalin, Enver and Alachkar, N and Bagnasco, S and Bouatou, Y and Becker, J. U and Cornell, L. D and Huyen, J. P. Duong and Gibson, I. W and Kraus, Edward S and Mannon, R. B and Naesens, M and Nickeleit, V and Nickerson, P and Segev, D. L and Singh, H. K and Stegall, M and Randhawa, P and Racusen, L and Solez, K and Mengel, M
American Journal of Transplantation, ISSN 1600-6135, 02/2018, Volume 18, Issue 2, pp. 293 - 307
The kidney sessions of the 2017 Banff Conference focused on 2 areas: clinical implications of inflammation in areas of interstitial fibrosis and tubular... 
molecular biology | pathology/histopathology | translational research/science | classification systems: Banff classification | kidney transplantation/nephrology | rejection | SURGERY | MOLECULAR ASSESSMENT | CLASSIFICATION | TRANSPLANT RECIPIENTS | RENAL-ALLOGRAFTS | TRANSPLANTATION | C4D | ACUTE HUMORAL REJECTION | IMMUNOSUPPRESSION | INFLAMMATION | BIOPSIES | DONOR-SPECIFIC ANTIBODIES | Inflammation - pathology | Prognosis | Humans | Graft Rejection - etiology | Graft Rejection - diagnosis | Inflammation - etiology | Isoantibodies - immunology | Research Report | T-Lymphocytes - immunology | Inflammation - diagnosis | High-Throughput Nucleotide Sequencing - methods | Graft Rejection - pathology | Postoperative Complications | Kidney Transplantation - adverse effects | Viral antibodies | Clinical trials | Antibodies | T cells | Molecular biology | Atrophy | Lymphocytes | Fibrosis | Lymphocytes T | Diagnosis | Graft rejection | Index Medicus | nephrology | pathology | kidney transplantation | science | histopathology | translational research | Meeting Reports | Meeting Report
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6. Full Text Clinical implications for the use of a biomarker for subclinical rejection – Conflating arguments cause a disconnection between the premise and the conclusion
by Friedewald, John and Abecassis, Michael
American Journal of Transplantation, ISSN 1600-6135, 07/2019, Volume 19, Issue 7, pp. 2141 - 2142
rejection: subclinical | translational research/science | biomarker | kidney transplantation/nephrology | nephrology | SURGERY | subclinical | kidney transplantation | science | translational research | rejection | TRANSPLANTATION
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7. Full Text The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology
by Loupy, A and Haas, M and Solez, K and Racusen, L and Glotz, D and Seron, D and Nankivell, B. J and Colvin, R. B and Afrouzian, M and Akalin, E and Alachkar, N and Bagnasco, S and Becker, J. U and Cornell, L and Drachenberg, C and Dragun, D and Kort, H and Gibson, I. W and Kraus, E. S and Lefaucheur, C and Legendre, C and Liapis, H and Muthukumar, T and Nickeleit, V and Orandi, B and Park, W and Rabant, M and Randhawa, P and Reed, E. F and Roufosse, C and Seshan, S. V and Sis, B and Singh, H. K and Schinstock, C and Tambur, A and Zeevi, A and Mengel, M
American Journal of Transplantation, ISSN 1600-6135, 01/2017, Volume 17, Issue 1, pp. 28 - 41
The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in Vancouver, Canada, reviewed the clinical impact of updates of... 
rejection: antibody‐mediated | translational research/science | pathology/histopathology | TCMR | organ transplantation in general | clinical research/practice | kidney transplantation/nephrology | ABMR | rejection: subclinical | rejection: T cell mediated | rejection | rejection: T cell mediated (TCMR) | rejection: antibody-mediated (ABMR) | SURGERY | practice | pathology | TRANSPLANTATION BIFQUIT REPRODUCIBILITY | kidney transplantation | histopathology | GRAFT FAILURE | TRANSPLANTATION | nephrology | MICROARRAY DIAGNOSIS | translational research | QUALITY-ASSURANCE | RENAL-ALLOGRAFT REJECTION | clinical research | ANTIBODY-MEDIATED REJECTION | COMPLEMENT-BINDING | science | BIOPSIES | NON-HLA ANTIBODIES | DONOR-SPECIFIC ANTIBODIES | Complement C4b - immunology | Humans | Peptide Fragments - immunology | Isoantibodies - immunology | Graft Rejection - etiology | Research Report | Graft Rejection - classification | Arteritis - immunology | Graft Rejection - pathology | Kidney Transplantation - adverse effects | Viral antibodies | Transplantation of organs, tissues, etc | Antibodies | T cells | Transplants & implants | Pathology | Classification | Atrophy | Syngeneic grafts | Fibrosis | Clinical trials | Pancreas transplantation | Histocompatibility antigen HLA | Lymphocytes T | Gene expression | Graft rejection | Index Medicus | Meeting Reports | Meeting Report | rejection: antibody‐mediated (ABMR)
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8. Full Text Sitagliptin treatment increases GLP‐1 without improving diabetes outcomes after total pancreatectomy with islet autotransplantation
by McEachron, Kendall R and Beilman, Gregory J and Bellin, Melena D
American Journal of Transplantation, ISSN 1600-6135, 03/2019, Volume 19, Issue 3, pp. 958 - 959
clinical trial | islet transplantation | autotransplantation | translational research/science | clinical research/practice | SURGERY | TRANSPLANTATION | Autografts | Sitagliptin | Diabetes therapy | Diabetes mellitus
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9. Full Text Towards a precision medicine approach to positive crossmatch transplantation: Impact on response to therapy
by Loupy, Alexandre and Bouatou, Yassine and Aubert, Olivier
American Journal of Transplantation, ISSN 1600-6135, 06/2019, Volume 19, Issue 6, pp. 1611 - 1613
The use of an integrated approach, combining the characteristics of donor specific antibodies and flow crossmatch, improves the risk stratification in... 
rejection: antibody‐mediated | editorial/personal viewpoint | pathology/histopathology | translational research/science | kidney transplantation/nephrology | alloantibody | ABMR | Transplants & implants | Histocompatibility testing | Kidney transplantation
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10. Full Text Histological picture of ABMR without HLA‐DSA: Temporal dynamics of effector mechanisms are relevant in disease reclassification
by Senev, Aleksandar and Callemeyn, Jasper and Lerut, Evelyne and Emonds, Marie‐Paule and Naesens, Maarten
American Journal of Transplantation, ISSN 1600-6135, 03/2019, Volume 19, Issue 3, pp. 954 - 955
rejection: antibody‐mediated | translational research/science | clinical research/practice | kidney transplantation/nephrology | alloantibody | ABMR | histocompatibility | immunobiology | rejection: antibody-mediated (ABMR) | SURGERY | TRANSPLANTATION | Reclassification | Histocompatibility antigen HLA
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11. Full Text Strategies to Incorporate Translational Research Science into Clinical Trials in Breast Cancer
by Fumagalli, Debora and Desmedt, Christine and Piccart, Martine and Sotiriou, Christos
Current Breast Cancer Reports, ISSN 1943-4588, 12/2010, Volume 2, Issue 4, pp. 208 - 213
The advent of molecular oncology, accompanied by a whole new range of high-throughput experimental methods and their related technologies, has revealed that... 
Clinical trials | New target identification | Internal Medicine | Oncology | Breast cancer | Drug development | Predictive signatures | Translational research | Medicine & Public Health | Biomarkers of efficacy | Prognostic signatures | Surgical Oncology | Patient selection | Breast international group
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12. Full Text Reply to “Predictive Modeling of Tacrolimus Dose Requirements: All That Is Gold Does Not Glitter”
by Damon, C and Pallet, N
American Journal of Transplantation, ISSN 1600-6135, 04/2017, Volume 17, Issue 4, pp. 1146 - 1146
translational research/science | genetics | immunosuppression/immune modulation | clinical research/practice | kidney transplantation/nephrology | genomics | immunosuppressant | calcineurin inhibitor: tacrolimus
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13. Full Text Chimerism, Graft Survival, and Withdrawal of Immunosuppressive Drugs in HLA Matched and Mismatched Patients After Living Donor Kidney and Hematopoietic Cell Transplantation
by Scandling, J. D and Busque, S and Shizuru, J. A and Lowsky, R and Hoppe, R and Dejbakhsh‐Jones, S and Jensen, K and Shori, A and Strober, J. A and Lavori, P and Turnbull, B. B and Engleman, E. G and Strober, S
American Journal of Transplantation, ISSN 1600-6135, 03/2015, Volume 15, Issue 3, pp. 695 - 704
Complete immunosuppressive drug withdrawal without subsequent rejection was accomplished in fully HLA‐matched kidney transplant patients with persistent mixed... 
tolerance: clinical | bone marrow/hematopoietic stem cell transplantation | translational research/science | tolerance: chimerism | clinical research/practice | kidney transplantation/nephrology | SURGERY | practice | TOLERANCE | kidney transplantation | BONE-MARROW | RENAL-TRANSPLANTATION | PERIPHERAL-BLOOD | MAINTENANCE IMMUNOSUPPRESSION | bone marrow | TRANSPLANTATION | nephrology | clinical research | science | DISEASE | hematopoietic stem cell transplantation | REGULATORY T-CELLS | translational research | Humans | Middle Aged | Hematopoietic Stem Cell Transplantation | Graft Survival | Male | Kidney Transplantation | Living Donors | Young Adult | Adult | Female | Chimerism | Immunosuppressive Agents - administration & dosage | Cohort Studies | Drugs | Transplantation | Hematopoietic stem cells | Donation of organs, tissues, etc | Haplotypes | Transplants & implants | Drug dosages | Index Medicus
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14. Full Text Small bowel and abdominal wall transplantation: A novel technique for synchronous revascularization
by Erdmann, Detlev and Atia, Andrew and Phillips, Brett T and Mithani, Suhail K and Avashia, Yash J and Hollister, Beth A and Cendales, Linda C and Ravindra, Kadiyala V and Sudan, Debra L
American Journal of Transplantation, ISSN 1600-6135, 07/2019, Volume 19, Issue 7, pp. 2122 - 2126
Abdominal wall transplantation ( AWT ) was introduced in 1999 in the context of reconstruction of complex abdominal wall defects in conjunction with visceral... 
translational research/science | vascularized composite and reconstructive transplantation | intestine/multivisceral transplantation | anatomy | clinical research/practice | tissue/organ engineering | SURGERY | practice | intestine | organ engineering | clinical research | science | tissue | translational research | multivisceral transplantation | TRANSPLANTATION | Abdominal wall | Transplantation | Intestine | Abdomen
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15. Full Text Towards donor lung recovery—gene expression changes during ex vivo lung perfusion of human lungs
by Yeung, Jonathan C and Zamel, Ricardo and Klement, William and Bai, Xiao‐Hui and Machuca, Tiago N and Waddell, Thomas K and Liu, Mingyao and Cypel, Marcelo and Keshavjee, Shaf
American Journal of Transplantation, ISSN 1600-6135, 06/2018, Volume 18, Issue 6, pp. 1518 - 1526
We and others have demonstrated that acellular normothermic ex vivo lung perfusion of high‐risk donor lungs can result in posttransplant outcomes equivalent to... 
molecular biology | expression | organ acceptance | translational research/science | lung transplantation/pulmonology | mRNA | basic (laboratory) research/science | organ perfusion and preservation | molecular biology: mRNA/mRNA expression | Genetic research | Transplantation of organs, tissues, etc | Gene expression | Analysis | Genes
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16. Full Text The first case of ischemia‐free organ transplantation in humans: A proof of concept
by He, Xiaoshun and Guo, Zhiyong and Zhao, Qiang and Ju, Weiqiang and Wang, Dongping and Wu, Linwei and Yang, Lu and Ji, Fei and Tang, Yunhua and Zhang, Zhiheng and Huang, Shanzhou and Wang, Linhe and Zhu, Zebin and Liu, Kunpeng and Zhu, Yanling and Gao, Yifang and Xiong, Wei and Han, Ming and Liao, Bing and Chen, Maogen and Ma, Yi and Zhu, Xiaofeng and Huang, Wenqi and Cai, Changjie and Guan, Xiangdong and Li, Xian Chang and Huang, Jiefu
American Journal of Transplantation, ISSN 1600-6135, 03/2018, Volume 18, Issue 3, pp. 737 - 744
Ischemia and reperfusion injury ( IRI ) is an inevitable event in conventional organ transplant procedure and is associated with significant mortality and... 
liver allograft function/dysfunction | surgical technique | translational research/science | organ procurement | clinical research/practice | liver transplantation/hepatology | organ perfusion and preservation | SURGERY | practice | ACTIVATION | CIRCULATORY DEATH | REPERFUSION INJURY | hepatology | PROCUREMENT | dysfunction | TRANSPLANTATION | PRESERVATION | clinical research | science | translational research | PERFUSION | MACHINE | ALLOGRAFTS | liver allograft function | PORCINE LIVERS | liver transplantation | CLINICAL-OUTCOMES | Transplantation of organs, tissues, etc | Ischemia | Health aspects | Liver cirrhosis | Liver | Liver diseases | Transplants & implants | Preservation | Hepatocellular carcinoma | Inflammation | Epithelium | Morbidity | Endothelium | Graft rejection | Steatosis | Cirrhosis | Reperfusion | Allografts | Perfusion | Liver transplantation
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17. Full Text Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC‐Specific Chimeric Antigen Receptor
by Noyan, F and Zimmermann, K and Hardtke‐Wolenski, M and Knoefel, A and Schulde, E and Geffers, R and Hust, M and Huehn, J and Galla, M and Morgan, M and Jokuszies, A and Manns, M. P and Jaeckel, E
American Journal of Transplantation, ISSN 1600-6135, 04/2017, Volume 17, Issue 4, pp. 917 - 930
CD 4 + CD 25 high FOXP 3 + regulatory T cells (Tregs) are involved in graft‐specific tolerance after solid organ transplantation. However, adoptive transfer of... 
translational research/science | immunosuppression/immune modulation | T cell biology | tissue (nonvascularized) transplantation | gene therapy | immunobiology | tolerance: experimental | tolerance | basic (laboratory) research/science | SURGERY | basic (laboratory) research | LIVER-TRANSPLANTATION | INSTABILITY | immunosuppression | TRANSPLANTATION | THERAPY | TRANSPLANTATION TOLERANCE | science | IN-VIVO | FREQUENCY | DISEASE | ENRICHMENT | translational research | GENERATION | immune modulation | Graft Survival - immunology | HLA-A2 Antigen - immunology | Graft Rejection - prevention & control | Humans | Receptors, Interleukin-2 - immunology | T-Lymphocytes, Regulatory - immunology | Allografts | Animals | Mice, Inbred NOD | Receptors, Antigen, T-Cell - immunology | Mice | Graft Rejection - immunology | Transplantation Tolerance - immunology | Antigens | Epigenetic inheritance | Immunotherapy | Transplantation of organs, tissues, etc | T cells | Cells | Graft rejection | Lymphocytes | T cell receptors | Index Medicus
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