X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (151) 151
biochemistry & molecular biology (138) 138
humans (128) 128
tri-snrnp (112) 112
u4/u6.u5 tri-snrnp (92) 92
rna splicing (80) 80
cell biology (74) 74
pre-messenger-rna (72) 72
saccharomyces-cerevisiae (71) 71
spliceosomes - metabolism (64) 64
spliceosome (63) 63
proteins (61) 61
animals (55) 55
rna (52) 52
protein (50) 50
article (48) 48
crystal-structure (47) 47
rna precursors - metabolism (47) 47
splicing (46) 46
yeast (43) 43
mutation (42) 42
models, molecular (41) 41
pre-mrna splicing (41) 41
cryo-em structure (38) 38
spliceosomes - chemistry (37) 37
protein binding (36) 36
ribonucleoproteins, small nuclear - metabolism (35) 35
rna precursors - genetics (33) 33
spliceosomes (33) 33
ribonucleoprotein, u4-u6 small nuclear - metabolism (32) 32
hela cells (30) 30
multidisciplinary sciences (30) 30
complex (28) 28
messenger-rna (28) 28
research (28) 28
rna-binding proteins - metabolism (28) 28
spliceosomes - genetics (28) 28
u4/u6-center-dot-u5 tri-snrnp (27) 27
analysis (26) 26
identification (26) 26
molecular biology (26) 26
molecular sequence data (26) 26
small nuclear ribonucleoprotein (26) 26
rna splicing - genetics (25) 25
alternative splicing (24) 24
amino acid sequence (24) 24
genetics & heredity (24) 24
messenger rna (24) 24
retinitis pigmentosa - genetics (24) 24
ribonucleoprotein, u4-u6 small nuclear - genetics (24) 24
rna, small nuclear - metabolism (24) 24
catalysis (23) 23
saccharomyces cerevisiae proteins - metabolism (23) 23
u5 snrnp (23) 23
base sequence (22) 22
cryoelectron microscopy (22) 22
introns (22) 22
nuclear proteins - metabolism (22) 22
protein conformation (22) 22
saccharomyces cerevisiae - genetics (22) 22
in-vitro (21) 21
ribonucleoprotein, u5 small nuclear - metabolism (21) 21
saccharomyces cerevisiae - metabolism (21) 21
spliceosomes - ultrastructure (21) 21
electron microscopy (20) 20
gene expression (20) 20
retinitis pigmentosa (20) 20
ribonucleoproteins, small nuclear - genetics (20) 20
rna helicases - metabolism (20) 20
small nuclear-rna (20) 20
angstrom resolution (19) 19
catalytic activation (19) 19
dominant retinitis-pigmentosa (19) 19
nucleic acid conformation (19) 19
physiological aspects (19) 19
rna splicing factors (19) 19
rna, messenger - metabolism (19) 19
in-vivo (18) 18
ribonucleoproteins (18) 18
ribonucleoproteins, small nuclear - chemistry (18) 18
rna, small nuclear - chemistry (18) 18
rna-binding proteins - genetics (18) 18
structural basis (18) 18
u6 snrna (18) 18
environment and public health (17) 17
molecular architecture (17) 17
ribonucleic acid--rna (17) 17
3-dimensional structure (16) 16
binding (16) 16
nuclear proteins - genetics (16) 16
rna splicing - physiology (16) 16
transcription (16) 16
binding sites (15) 15
biochemical research methods (15) 15
cell line (15) 15
domain (15) 15
eye proteins - genetics (15) 15
mrna (15) 15
mutations (15) 15
phosphorylation (15) 15
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


by Yan, CY and Wan, RX and Bai, R and Huang, GXY and Shi, YG
SCIENCE, ISSN 0036-8075, 08/2016, Volume 353, Issue 6302, pp. 904 - 911
Pre-messenger RNA (pre-mRNA) splicing is carried out by the spliceosome, which undergoes an intricate assembly and activation process. Here, we report an... 
METAL-ION CATALYSIS | 3-DIMENSIONAL STRUCTURE | GROUP-II INTRON | U4/U6.U5 TRI-SNRNP | MESSENGER-RNA | SMALL NUCLEAR-RNA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | G-PATCH PROTEIN | CRYO-EM STRUCTURE
Journal Article
by Wan, RX and Yan, CY and Bai, R and Huang, GXY and Shi, YG
SCIENCE, ISSN 0036-8075, 08/2016, Volume 353, Issue 6302, pp. 895 - 904
Each cycle of pre-messenger RNA splicing, carried out by the spliceosome, comprises two sequential transesterification reactions, which result in the removal... 
METAL-ION CATALYSIS | 3-DIMENSIONAL STRUCTURE | 2ND STEP | U4/U6.U5 TRI-SNRNP | SMALL NUCLEAR-RNA | ACTIVE-SITE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ELECTRON-MICROSCOPY | 19 COMPLEX | CRYO-EM STRUCTURE
Journal Article
Cell, ISSN 0092-8674, 2009, Volume 136, Issue 4, pp. 701 - 718
Journal Article
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, ISSN 1943-0264, 11/2019, Volume 11, Issue 11
The spliceosome is a highly complex, dynamic ribonucleoprotein molecular machine that undergoes numerous structural and compositional rearrangements that lead... 
HUMAN SPLICEOSOME | U4/U6.U5 TRI-SNRNP | PROTEIN | BRANCH SITE | MECHANISTIC INSIGHTS | MOLECULAR ARCHITECTURE | U2 SNRNP | STEP | PROTEOMIC ANALYSIS | ACTIVATED SPLICEOSOME | CELL BIOLOGY
Journal Article