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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2019, Volume 116, Issue 48, pp. 24252 - 24258
Chronic lymphocytic leukemia (CLL) is the most common human leukemia, and dysregulation of tRNA-derived short noncoding RNA (t5RNA) (tRF-1) expression is an... 
tsRNAs | NONCODING RNA | tRNA fragments | MULTIDISCIPLINARY SCIENCES | tRFs | PROGRESSION | MICRORNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2016, Volume 113, Issue 18, pp. 5071 - 5076
Journal Article
Mechanisms of Ageing and Development, ISSN 0047-6374, 04/2017, Volume 163, pp. 15 - 22
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2017, Volume 114, Issue 30, pp. 8071 - 8076
Small, noncoding RNAs are short untranslated RNA molecules, some of which have been associated with cancer development. Recently we showed that a class of... 
tRF | tDR | tRNA fragments | ncRNA | tsRNA | MULTIDISCIPLINARY SCIENCES | C-MYC | PTEN | PROLIFERATION | CERAMIDE | BREAST | SIGNALING PATHWAY | TRANSFER-RNA FRAGMENTS | STRESS | Neoplasms - metabolism | A549 Cells | Humans | HEK293 Cells | Case-Control Studies | Oncogenes | RNA, Small Untranslated - metabolism | Index Medicus | Biological Sciences
Journal Article
by He, X and Li, F and Bor, B and Koyano, K and Cen, L and Xiao, X and Shi, W and Wong, D.T.W
Journal of Dental Research, ISSN 0022-0345, 10/2018, Volume 97, Issue 11, pp. 1236 - 1243
Coevolution of the human host and its associated microbiota has led to sophisticated interactions to maintain a delicate homeostasis. Emerging evidence... 
tsRNAs | oral microbiome | sRNAs | antimicrobials | cross-domain interactions | microbial-host interaction | BACTERIA | IMMUNE HOMEOSTASIS | RECOGNITION | PROLIFERATION | TRANSLATION | CANCER | NONCODING RNAS | PERIODONTITIS | DENTISTRY, ORAL SURGERY & MEDICINE | PROGRESSION | MICRORNA | Research Reports
Journal Article
Cell Reports, ISSN 2211-1247, 12/2018, Volume 25, Issue 12, pp. 3356 - 3370.e4
The discovery of microRNA (miRNA) sorting into extracellular vesicles (EVs) revealed a novel mode of intercellular communication and uncovered a link between... 
T lymphocyte | tRNA fragment | extracellular vesicle | exosome | tsRNA | READ ALIGNMENT | BIOGENESIS | EXOSOMES | SYNTHETASE | DEATH | SECRETION | EXPRESSION | NEXT-GENERATION | CDNA LIBRARIES | MICRORNA | CELL BIOLOGY
Journal Article
Diabetologia, ISSN 0012-186X, 8/2018, Volume 61, Issue 8, pp. 1862 - 1876
Journal Article
Advances in Cancer Research, ISSN 0065-230X, 2017, Volume 135, pp. 173 - 187
Noncoding RNAs are untranslated RNA molecules that can be divided into two main types: infrastructural, including transfer RNAs (tRNAs) and ribosomal RNAs... 
tsRNAs | MicroRNAs | tRNA-derived fragments | LONG NONCODING RNAS | DNA METHYLATION | BIOGENESIS | ONCOLOGY | POLYMERASE III | GENE-EXPRESSION | CHRONIC LYMPHOCYTIC-LEUKEMIA | CELL-PROLIFERATION | FRAGMENTS TRFS | TRANSCRIPTION TERMINATION | GENOME | RNA, Transfer - genetics | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Neoplasms - genetics | Humans
Journal Article
by Kim, HK
MOLECULES AND CELLS, ISSN 1016-8478, 10/2019, Volume 42, Issue 10, pp. 687 - 692
Transfer RNA-derived small RNAs (tsRNAs) play a role in various cellular processes. Accumulating evidence has revealed that tsRNAs are deeply implicated in... 
tRNA | MESSENGER-RNA | ASSOCIATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | translation | tRF | STRESS | CLEAVAGE | BINDING | tsRNA | REVEALS | CELL BIOLOGY | Minireview
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 2016, Volume 230, Issue 3, pp. F13 - F18
Many findings support the hypothesis that metabolic changes associated with environmental factors can be transmitted from father to offspring. The molecular... 
RNA modification | TsRNA | Acquired metabolic disorder | Intergenerational inheritance | Animals | Epigenesis, Genetic - genetics | Humans | Metabolic Diseases - genetics | Male | DNA Methylation - genetics | Spermatozoa - metabolism | RNA - genetics
Journal Article
Cell Reports, ISSN 2211-1247, 12/2019, Volume 29, Issue 12, pp. 3816 - 3824.e4
tRNA-derived small RNAs (tsRNAs) have been implicated in many cellular processes, yet the detailed mechanisms are not well defined. We previously found that... 
ribosomal proteins | translation | tRF | tRNA fragments | tsRNA | tRNA-derived small RNAs | INHIBITION | MESSENGER-RNA | DATABASE | BIOGENESIS | DRAFT | IN-VIVO | TRANSCRIPTION | GENE-EXPRESSION | IDENTIFICATION | REVEALS | CELL BIOLOGY
Journal Article
Advances in Biological Regulation, ISSN 2212-4926, 01/2019, Volume 71, pp. 219 - 223
By using chronic lymphocytic leukemia as target for discovery in cancer pathogenesis we discovered that the great majority of CLLs (75–85%) carry a deletion of... 
BCL2 | CLL | ROR1 | miR-15/16 | tRNA derived fragments | tsRNA | Regulators | Chronic lymphatic leukemia | Pathogenesis | Leukemia | MiRNA | Lymphatic leukemia | Patients | Proteins | Clonal deletion | Lymphocytes B | Ribonucleic acids | Monoclonal antibodies | Deletion | Remission | Cancer | miR-15
Journal Article
Science China Life Sciences, ISSN 1674-7305, 02/2018, Volume 61, Issue 2, pp. 155 - 161
Rather than random degradation products, the 18 to 40 nucleotides (nt) transfer RNA-derived small RNAs (tsRNAs) are RNA species generated specifically from... 
tsRNAs | tRNA derived-small RNAs | biogenesis | plant | OXIDATIVE STRESS | CHLOROPLAST | PROLIFERATION | IDENTIFICATION | TRANSLATION | LAND PLANTS | TRANSCRIPTS | FRAGMENTS | BIOLOGY | ARABIDOPSIS | EXPRESSION | Biodegradation | Cell proliferation | Post-transcription | Degradation products | Heredity | Nucleotides | Gene expression | Ribonucleic acid--RNA | Transfer RNA
Journal Article
Journal of Extracellular Vesicles, ISSN 2001-3078, 01/2015, Volume 4, Issue 1, pp. 28665 - 16
Penetration of skin, migration through tissues and establishment of long-lived intravascular partners require Schistosoma parasites to successfully manipulate... 
tsRNAs | Schistosoma mansoni | extracellular vesicles | miRNAs | platyhelminth | small non-coding RNAs | proteome | Pathogens | Parasitology | Funding | Colleges & universities | Infections | Biosynthesis | Parasites | Blood | Tropical diseases | Proteins | MicroRNAs | Proteomics | Biomarkers | Communication
Journal Article
Cancer Management and Research, ISSN 1179-1322, 2019, Volume 11, pp. 3945 - 3956
Purpose: As a malignancy that develops from breast tissue, breast cancer has been widely regarded as the most common type of cancer threatening the health of... 
Malignancy | Tsrna | MDA-mb-231 cells | Predictive marker | BIOMARKERS | DIAGNOSIS | malignancy | ONCOLOGY | MDA-MB-231 cells | predictive marker | MICRORNAS | tsRNA
Journal Article
by Tan, DM and Tan, Y and Duan, EK
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, ISSN 1000-3282, 11/2019, Volume 46, Issue 11, pp. 1063 - 1072
tRNA-derived small RNAs (tsRNAs) is a type of newly discovered non-coding small RNA, which is derived from mature tRNA or tRNA precursor and exists in various... 
ANTICODON STEM | RNA modification | protein translation | METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RNA-DERIVED FRAGMENTS | CELL-PROLIFERATION | biomarker | TRANSLATION | transposon | RNA-sequencing | BIOPHYSICS | EXTRACELLULAR VESICLES | MESSENGER-RNA | STRESS | SMALL NONCODING RNAS | tsRNA | REVEALS
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 12/2016, Volume 7, Issue 2016, p. 1938
Along with the well-studied microRNA (miRNA) and small interfering RNA (siRNA) is a new class of transfer RNA-derived small RNA (tsRNA), which has recently... 
TsRNA | Phytophthora | RNA silencing | Gene regulation | Oomycete | EUKARYOTE GIARDIA-LAMBLIA | OXIDATIVE STRESS | GENOMIC SEQUENCE | DNA-DAMAGE | SIRNAS | CLEAVAGE | VIRULENCE | TRANSLATION | CELL-DEATH | PLANT SCIENCES | oomycete | gene regulation | PIWI PROTEINS | tsRNA | RNA | Physiological aspects | Genetic aspects | Research | Water molds | Gene expression | Identification and classification
Journal Article