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Immunological Reviews, ISSN 0105-2896, 03/2016, Volume 270, Issue 1, pp. 152 - 164
Summary Recombinant immunotoxins (RITs) are chimeric proteins designed to treat cancer. They are made up of an Fv or Fab that targets an antigen on a cancer... 
neutralizing antibodies | mesothelioma | immunotherapy | anti‐drug antibodies | mesothelin | Mesothelin | Mesothelioma | Anti-drug antibodies | Neutralizing antibodies | Immunotherapy | anti-drug antibodies | ADVANCED SOLID TUMORS | IMMUNOLOGY | EXOTOXIN-A MUTANTS | SURFACE-EXPOSED RESIDUES | B-CELL | PHASE-I TRIAL | REDUCED IMMUNOGENICITY | SITE-SPECIFIC MANNER | T-CELL EPITOPE | PSEUDOMONAS EXOTOXIN | HEMATOLOGIC MALIGNANCIES | Epitope Mapping | Sequence Deletion | Virulence Factors - genetics | Humans | Immunosuppressive Agents - therapeutic use | Immunotoxins - adverse effects | Epitopes, B-Lymphocyte - immunology | Virulence Factors - immunology | Recombinant Fusion Proteins | Antibodies, Neutralizing - immunology | Neoplasms - therapy | Immunotoxins - administration & dosage | Immunoglobulin Fragments - therapeutic use | Bacterial Toxins - genetics | Immunotoxins - chemistry | Epitopes, T-Lymphocyte - immunology | Drug Therapy, Combination | Immunosuppressive Agents - administration & dosage | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - immunology | Drug Administration Routes | Immunotoxins - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Exotoxins - chemistry | Polyethylene Glycols | Bacterial Toxins - immunology | Exotoxins - immunology | Clinical Trials as Topic | Virulence Factors - chemistry | Bacterial Toxins - chemistry | ADP Ribose Transferases - genetics | Immunotoxins - genetics | Animals | Genetic Engineering | Immunoglobulin Fragments - immunology | Immunotoxins - therapeutic use | Neoplasms - immunology | Exotoxins - genetics | Antibody Formation | Antigens - immunology | Mice | Antibodies, Monoclonal, Humanized - immunology | Biological products | Antibody-toxin conjugates | Health aspects | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 06/2017, Volume 8, Issue 1, p. 15618
Journal Article
Science, ISSN 0036-8075, 12/2015, Volume 350, Issue 6266, pp. 1387 - 1390
Journal Article
Journal Article
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2012, Volume 12, Issue 7, pp. 703 - 708
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2007, Volume 13, Issue 1, pp. 54 - 61
Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune response, whereas other DNA-damaging agents such as etoposide and... 
MEDICINE, RESEARCH & EXPERIMENTAL | CLEARANCE | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR | CHAPERONE | CELL BIOLOGY | DYING CELLS | APOPTOTIC CELLS | SURFACE CALRETICULIN | ENDOPLASMIC-RETICULUM | ENCODING CALRETICULIN | ANTIGEN | Apoptosis - drug effects | Colonic Neoplasms - drug therapy | Dendritic Cells - immunology | Electrophoresis, Gel, Two-Dimensional | Immunoblotting | Antineoplastic Agents - therapeutic use | Protein Transport - drug effects | Calreticulin - genetics | Colonic Neoplasms - metabolism | Cell Cycle Proteins - antagonists & inhibitors | RNA Interference | Anthracyclines - pharmacology | Neoplasms, Experimental - immunology | Calreticulin - metabolism | Antigens, Differentiation - metabolism | Antineoplastic Agents - pharmacology | Cell Membrane - metabolism | Protein Phosphatase 1 | Cell Membrane - drug effects | Mitomycin - therapeutic use | Cell Cycle Proteins - metabolism | Phagocytosis - immunology | Etoposide - pharmacology | Etoposide - therapeutic use | Recombinant Proteins - pharmacology | Mitomycin - pharmacology | Animals | Apoptosis - immunology | Mice, Nude | Colonic Neoplasms - pathology | Cell Line, Tumor | Cell Membrane - immunology | Mice | Mice, Inbred BALB C | Anthracyclines - therapeutic use | Calreticulin - immunology | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Chemotherapy | Immunology | DNA damage | Rodents | Cancer | Apoptosis | Tumors | Antigens, Differentiation | Cell Membrane | Anthracyclines | Dendritic Cells | Recombinant Proteins | Life Sciences | Calreticulin | Neoplasms, Experimental | Mitomycin | Etoposide | Antineoplastic Agents | Protein Transport | Phagocytosis | Cell Cycle Proteins | Colonic Neoplasms
Journal Article