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Behavioural Brain Research, ISSN 0166-4328, 05/2012, Volume 231, Issue 1, pp. 130 - 137
Journal Article
Psychopharmacology, ISSN 0033-3158, 4/2011, Volume 214, Issue 4, pp. 819 - 828
A complex relationship exists among stressful situations, body's reaction to stress, and the onset of clinical depression. Chronic unpredictable stressors can... 
Antidepressant | Neurosciences | Biomedicine | Unpredictable chronic stress | TNF-α | Depression | Sesamol | Pharmacology/Toxicology | Psychiatry | Stress | LIPID-PEROXIDATION | TNF-alpha | PSYCHIATRY | NITRIC-OXIDE SYNTHASE | ANTIDEPRESSANT TREATMENTS | MAJOR DEPRESSION | CHRONIC VARIABLE STRESS | NEUROSCIENCES | INDUCED OXIDATIVE STRESS | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | RAT HIPPOCAMPUS | INDUCED ANHEDONIA | PITUITARY-ADRENAL AXIS | Brain - enzymology | Motor Activity - drug effects | Male | Stress, Psychological - psychology | Brain - metabolism | Depression - drug therapy | Depression - metabolism | Stress, Psychological - metabolism | Lipid Peroxidation - drug effects | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Benzodioxoles - therapeutic use | Disease Models, Animal | Phenols - pharmacology | Food Preferences - drug effects | Stress, Psychological - drug therapy | Mice, Inbred Strains | Antidepressive Agents - therapeutic use | Brain - drug effects | Animals | Phenols - therapeutic use | Psychopharmacology | Depression - psychology | Mice | Chronic Disease | Benzodioxoles - pharmacology | Antioxidants | Enzymes | Usage | Tumor necrosis factor | Analysis | Depression, Mental | Lipid peroxidation | Superoxide | Research | Antidepressants, Tricyclic | Biochemistry | Mental depression | Antidepressants
Journal Article
Psychopharmacology, ISSN 0033-3158, 11/2017, Volume 234, Issue 22, pp. 3385 - 3394
Saikosaponin D (SSD), a major bioactive component isolated from Radix Bupleuri, has been reported to exert neuroprotective properties.The present study was... 
Unpredictable chronic mild stress | Neurosciences | Biomedicine | Saikosaponin D | Depression | Hypothalamic-pituitary-adrenal axis | Hippocampal neurogenesis | Pharmacology/Toxicology | Psychiatry | Neurotrophic molecules | PSYCHIATRY | NEUROTROPHIC FACTOR | ANTIDEPRESSANT TREATMENT | ELEMENT-BINDING PROTEIN | FORCED SWIM TEST | MAJOR DEPRESSION | MODEL | NEUROSCIENCES | FLUOXETINE TREATMENT | PHARMACOLOGY & PHARMACY | GLUCOCORTICOID-RECEPTOR PHOSPHORYLATION | EXPRESSION | BRAIN | Depression - physiopathology | Oleanolic Acid - analogs & derivatives | Oleanolic Acid - pharmacology | Male | Hippocampus - drug effects | Stress, Psychological - psychology | Arousal - drug effects | Motivation - drug effects | Antidepressive Agents - pharmacology | Neurogenesis - drug effects | Corticosterone - blood | Phytotherapy | Receptors, Glucocorticoid - drug effects | Hypothalamo-Hypophyseal System - physiopathology | Hypothalamo-Hypophyseal System - drug effects | Pituitary-Adrenal System - physiopathology | Pituitary-Adrenal System - drug effects | Rats | Rats, Sprague-Dawley | Arousal - physiology | Animals | Motivation - physiology | Neurogenesis - physiology | Depression - psychology | Hippocampus - physiopathology | Receptors, Glucocorticoid - physiology | Saponins - pharmacology | Stress, Psychological - physiopathology | Prevention | Saponins | Hippocampus (Brain) | Health aspects | Neurogenesis | Depression, Mental | Immunohistochemistry | Neuroprotection | Brain | Sucrose | Glucocorticoids | Corticosterone | P elements | Body weight | Hypothalamus | Consolidation | Antidepressants | Rodents | Doublecortin protein | Sugars | Open-field behavior | Translocation | Cyclic AMP response element-binding protein | Nuclear transport | Studies | Brain-derived neurotrophic factor | Pituitary | Weight reduction | Hippocampus
Journal Article