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Virology, ISSN 0042-6822, 09/2018, Volume 522, pp. 106 - 121
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) , a latent gene of KSHV, was first identified as a FLICE-inhibitory protein (FLIP) protecting cells from... 
NF-κBs | p-RelA S468 | Spindle morphology | IKKε | RelA | VFLIP | NF-kappa Bs | DEATH DOMAIN | KSHV VFLIP | TUMOR PROGRESSION | DOMAIN-CONTAINING PROTEIN | ENCODED VFLIP | SARCOMA-ASSOCIATED HERPESVIRUS | FLICE-INHIBITORY PROTEIN | VIROLOGY | IKK epsilon | KAPOSIS-SARCOMA | ENDOTHELIAL-CELLS | p-RelA 5468 | NF-KAPPA-B
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 11/2017, Volume 36, Issue 1, pp. 167 - 9
Background: Apigenin is a flavonoid widely distributed in plant kingdom that exerts cytotoxic effects against a variety of solid and haematological cancers. In... 
Apigenin | KSHV | PEL | STAT3 | vFLIP | Autophagy | Apoptosis | p53 | PI3K/AKT/MTOR | PHOSPHORYLATION | ANTIOXIDANT FUNCTION | DOWN-REGULATION | FLAVONOID APIGENIN | CANCER | ONCOLOGY | RESISTANCE | KSHV LYTIC CYCLE | EXPRESSION | Care and treatment | Flavonoids | Flavones | Bioflavonoids | Physiological aspects | Lymphomas | Genetic aspects | Research | Tumor proteins | Studies | Phosphorylation | Dendritic cells | Cell cycle | Cancer therapies
Journal Article
by Ding, XY and Xu, JY and Wang, C and Feng, Q and Wang, QX and Yang, Y and Lu, HM and Wang, F and Zhu, KX and Li, W and Yan, Q and Gao, SJ and Lu, C
CELL DEATH AND DIFFERENTIATION, ISSN 1350-9047, 10/2019, Volume 26, Issue 10, pp. 1970 - 1986
Kaposi's sarcoma (KS), a highly invasive and angiogenic tumor of endothelial spindle-shaped cells, is the most common AIDS-associated cancer caused by... 
HIV-1 NEF | APOPTOSIS | VIRUS | KAPOSIS-SARCOMA | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SARCOMA-ASSOCIATED HERPESVIRUS | TRANSCRIPTION | LYTIC REPLICATION | CANCER | VFLIP | CELL BIOLOGY
Journal Article
ONCOGENE, ISSN 0950-9232, 05/2019, Volume 38, Issue 22, pp. 4340 - 4351
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV), a gamma-2 herpesvirus, is the causative agent of KS, primary effusion lymphoma (PEL), and a plasma cell... 
DNA-SEQUENCES | ACTIVATION | ENDOTHELIAL ICAM-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIMARY EFFUSION LYMPHOMA | CANCER | CELL BIOLOGY | GENE | ONCOLOGY | GENETICS & HEREDITY | HUMAN L1 ELEMENT | KAPPA-B PATHWAY | EXPRESSION | VFLIP | Infection | Development and progression | Non-Hodgkin's lymphomas | Sarcoma | Health aspects | Genomics
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 05/2019, Volume 93, Issue 10
MC159 is a viral FLIP (FLICE inhibitory protein) encoded by the molluscum contagiosum virus (MCV) enabling MCV to evade antiviral immunity and to establish... 
SH3 domain | APOPTOSIS | KAPPA-B ACTIVATION | MC159 | autophagy | MECHANISMS | protein-protein interactions | MOLECULES | REGULATOR | INHIBITION | VIROLOGY | GENE | AFFINITY | SH3BP4 | MVC | V-FLIP PROTEIN | vFLIP | BINDING
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2015, Volume 11, Issue 11, p. e1005255
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2011, Volume 415, Issue 2, pp. 305 - 312
► Viral FLIP has been shown to activate NF-κB signaling to confer cell survival. ► We investigated novel activity of vFLIP in chemosensitivity to anticancer... 
NF-κB | Anticancer drug | Chemotherapy | Bleomycin | vFLIP | KSHV
Journal Article
Journal of Virology, ISSN 0022-538X, 07/2006, Volume 80, Issue 14, pp. 7179 - 7185
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
LONG-TERM CULTURE | KSHV VFLIP | PROTEIN | VIROLOGY | PATHWAY | SHEAR-STRESS | GROWTH-FACTOR RECEPTOR-3 | TUMOR-CELLS | DEATH | LYTIC REPLICATION | EXPRESSION | Virus-Cell Interactions
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 04/2016, Volume 35, Issue 14, pp. 1797 - 1810
Journal Article
Molecular Cell, ISSN 1097-2765, 2008, Volume 30, Issue 5, pp. 620 - 631
Key to the pathogenicity of several viruses is activation of the canonical nuclear factor-κB (NF-κB) transcriptional pathway. Subversion of this tightly... 
MOLIMMUNO | SIGNALING | KSHV VFLIP | APOPTOSIS | DNA-SEQUENCES | DOMAIN | KAPOSI-SARCOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANHIDROTIC ECTODERMAL DYSPLASIA | GENE-EXPRESSION | NF-KAPPA-B | NEMO | IMMUNODEFICIENCY | CELL BIOLOGY
Journal Article
Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 10, pp. 1223 - 1232
Kaposi's sarcoma-associated herpesvirus (KSHV) K13/vFLIP (viral Flice-inhibitory protein) induces transcription of numerous genes through NF-kappa B... 
AIDS | endothelial cells | KSHV | Kaposi's sarcoma | NF-kB | vFLIP/K13 | KSHV VFLIP | IKK-GAMMA | ENZYME A20 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | DEPENDENT GENE-EXPRESSION | A20 INTERACTS | CELL BIOLOGY | KINASE COMPLEX | UBIQUITIN CHAINS | NF-kappa B | ONCOLOGY | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | ZINC-FINGER PROTEIN | Sarcoma, Kaposi - metabolism | Humans | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Viral Proteins - metabolism | DNA-Binding Proteins - metabolism | Transfection | Herpesvirus 8, Human - metabolism | Nuclear Proteins - biosynthesis | Tumor Necrosis Factor alpha-Induced Protein 3 | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | NF-kappa B - antagonists & inhibitors | Transduction, Genetic | Endothelial Cells - metabolism | Viral Proteins - genetics | Herpesvirus 8, Human - genetics | Nuclear Proteins - metabolism | Viral Proteins - antagonists & inhibitors | Sarcoma, Kaposi - virology | DNA-Binding Proteins - genetics | Intracellular Signaling Peptides and Proteins - biosynthesis | Sarcoma, Kaposi - pathology | Proteins - genetics | Animals | Proteins - metabolism | NF-kappa B - genetics | Endothelial Cells - cytology | Chemokine CXCL10 - secretion | Mice | Chemokine CXCL10 - metabolism | DNA-Binding Proteins - biosynthesis | Sarcoma, Kaposi - genetics | Cell proliferation | Cytokines | Transcription | Inflammation | regulatory proteins | IKK1 protein | Endothelial cells | FLICE-inhibitory protein | NF- Kappa B protein | Transcription activation | IP-10 protein | Chemokines | Tumors
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 01/2015, Volume 13, Issue 1, pp. 7 - 12
Journal Article