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Autophagy, ISSN 1554-8627, 07/2019, Volume 15, Issue 7, pp. 1214 - 1233
Mutations in the ER-associated VAPB/ALS8 protein cause amyotrophic lateral sclerosis and spinal muscular atrophy. Previous studies have argued that ER stress... 
autophagy | PI4KB | Vap33 | VAPA/VAPB | ALS8 | ER STRESS | DROSOPHILA MODEL | MEMBRANE-PROTEIN | ENDOPLASMIC-RETICULUM STRESS | AMYOTROPHIC-LATERAL-SCLEROSIS | C9ORF72 | CELL BIOLOGY | TRANSPORT | VAPA | VAPB | DISEASE | HEXANUCLEOTIDE REPEAT
Journal Article
FEBS Letters, ISSN 0014-5793, 02/2012, Volume 586, Issue 3, pp. 263 - 269
► We investigate the role of VapB in RANKL-induced osteoclast differentiation. ► Knock-down of VapB suppressed osteoclastogenesis. ► Over-expression of VapB... 
Osteoclast | NFATc1 | VapB | PLCγ2
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 2015, Volume 6, pp. 1 - 1
Fungal secondary metabolism has become an important research topic with great biomedical and biotechnological value. In the postgenomic era, understanding the... 
VapA-VipC-VapB | Methyltransferases | VelB-VeA-LaeA | LaeA | Velvet family | LlmF | Secondary metabolism | VosA | FUNGAL DEVELOPMENT | COMPLEX | velvet family | ASPERGILLUS-NIDULANS | FUNCTIONAL ROLES | GENE CLUSTERS | MICROBIOLOGY | VIRULENCE | methyltransferases | secondary metabolism | EXPRESSION | SEXUAL DEVELOPMENT
Journal Article
Virology, ISSN 0042-6822, 09/2019, Volume 535, pp. 210 - 217
Tomato yellow leaf curl virus (TYLCV) poses serious threat to tomato production worldwide, and the vector, Bemisia tabaci, plays a key role in the transmission... 
Proteins | Vegetable industry | Aleyrodidae | Molecular biology | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 07/2017, Volume 13, Issue 7, pp. 1250 - 1251
The endoplasmic reticulum (ER) and mitochondria form tight functional contacts that regulate several key cellular processes. The formation of these contacts... 
mitochondria-associated membranes | autophagy | calcium | VAPB | mitochondria | PTPIP51 | endoplasmic reticulum | CELL BIOLOGY | Index Medicus
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 04/2019, Volume 132, Issue 7, p. jcs220061
VAPB and VAPA are ubiquitously expressed endoplasmic reticulum membrane proteins that play key roles in lipid exchange at membrane contact sites. A mutant,... 
MOTOR-NEURONS | MUTANT | FFAT MOTIF | Neurodegenerative diseases | ER STRESS | PHOSPHATIDYLINOSITOL | MODEL | PLASMA-MEMBRANE | CELL BIOLOGY | Neuritogenesis | NSC34 cells | P56S MUTATION | Phosphatidylinositol-4-phosphate | MEMBRANE CONTACT SITES | PROTEIN VAPB | Endolysosomes
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2015, Volume 11, Issue 3, pp. e1005107 - e1005107
Journal Article
Journal Article
Arquivos de Neuro-Psiquiatria, ISSN 0004-282X, 10/2013, Volume 71, Issue 10, pp. 788 - 790
Journal Article
Current Biology, ISSN 0960-9822, 04/2018, Volume 28, Issue 8, pp. 1234 - 1245.e4
The endoplasmic reticulum (ER) is the site of biogenesis of the isolation membrane (IM, autophagosome precursor) and forms extensive contacts with IMs during... 
FIP200 | membrane contact | isolation membrane | VAPA/B | autophagosome | COMPLEX | TRANSPORT | CHOLESTEROL | VAPB | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | SITES | TRAFFICKING | ENDOPLASMIC-RETICULUM | AMYOTROPHIC-LATERAL-SCLEROSIS | LIPID-TRANSFER | CELL BIOLOGY | Proteins
Journal Article
Development (Cambridge), ISSN 0950-1991, 2017, Volume 144, Issue 12, pp. 2175 - 2186
The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotrophic lateral sclerosis. Secreted MSPds derived from the C.... 
Major sperm protein domain | Mitochondria | VAPA | VAPB | SMA | ALS | Amyotrophic lateral sclerosis | MSP | Striated muscle | SMN-1 | Spinal muscular atrophy | EARLY PATHOGENESIS | NERVOUS-SYSTEM | SOD1(G93A) MOUSE MODEL | DROSOPHILA-MELANOGASTER | DEVELOPMENTAL BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | MOTOR-NEURON DISEASE | CAENORHABDITIS-ELEGANS | SPINAL MUSCULAR-ATROPHY | MAJOR SPERM | PROTEIN VAPB | Caenorhabditis elegans Proteins - chemistry | Humans | Mitochondria, Muscle - metabolism | Genes, Helminth | Caenorhabditis elegans Proteins - metabolism | Male | Actin-Related Protein 2-3 Complex - metabolism | RNA Interference | Larva - growth & development | Protein Domains | Receptor-Like Protein Tyrosine Phosphatases - genetics | Actin-Related Protein 2 - metabolism | Membrane Proteins - metabolism | Germ Cells - metabolism | Sarcolemma - metabolism | SMN Complex Proteins - metabolism | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Signal Transduction | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Membrane Proteins - genetics | Larva - metabolism | Receptor-Like Protein Tyrosine Phosphatases - metabolism | Motor Neurons - metabolism | SMN Complex Proteins - antagonists & inhibitors | Animals | Membrane Proteins - chemistry | Amyotrophic Lateral Sclerosis - metabolism | Muscle, Striated - growth & development | Mutation | Muscle, Striated - metabolism | SMN Complex Proteins - genetics | Caenorhabditis elegans Proteins - genetics | Tyrosine | Body wall | Cell survival | Splicing | Secretion | RNA-mediated interference | Nervous system | mRNA | Skeletal muscle | Sclerosis | Actin | Localization | Protein-tyrosine-phosphatase | Index Medicus | 209
Journal Article
Current Biology, ISSN 0960-9822, 02/2017, Volume 27, Issue 3, pp. 371 - 385
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 07/2017, Volume 134, Issue 1, pp. 129 - 149
alpha-Synuclein is strongly linked to Parkinson's disease but the molecular targets for its toxicity are not fully clear. However, many neuronal functions... 
Calcium signaling | α-Synuclein | Mitochondria | Axonal transport | Autophagy | Endoplasmic reticulum | CELLS | OXIDATIVE STRESS | MITOFUSIN 2 | VAPB-PTPIP51 INTERACTION | CALCIUM HOMEOSTASIS | AXONAL-TRANSPORT | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | MOTOR-NEURON DEGENERATION | MUTATION | ANIMAL-MODELS | FAMILIAL PARKINSONS-DISEASE | alpha-Synuclein | Index Medicus | Original Paper
Journal Article