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Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2019, Volume 67, Issue 1, pp. 41 - 46
Bio-guided fractionation of the 70% ethanol extract of Belamcanda chinensis (L.) DC. revealed four new compounds, including 6"-O-acetylembinin (5),... 
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 30, pp. 24978 - 24989
Vascular smooth muscle cell (VSMC) trans-differentiation, or their switch from a contractile/quiescent to a secretory/inflammatory/migratory state, is known to... 
CROSS-TALK | MIGRATION | ALPHA-ACTIN | REPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | JAGGED1 | IL-1-BETA | GROWTH-FACTOR | DEPENDENT PATHWAY | RECEPTORS | BETA | Gene Expression Regulation, Enzymologic - drug effects | Inflammation - pathology | Interleukin-1beta - pharmacology | Rats, Wistar | Receptors, Notch - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Male | Receptors, Notch - genetics | Inflammation - metabolism | Interleukin-1beta - metabolism | Cell Transdifferentiation | Carotid Artery Injuries - genetics | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Adenylyl Cyclases - biosynthesis | Myocytes, Smooth Muscle - enzymology | Rats | Repressor Proteins - genetics | Up-Regulation - genetics | Signal Transduction - genetics | Up-Regulation - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Repressor Proteins - biosynthesis | Signal Transduction - drug effects | Gene Expression Regulation, Enzymologic - genetics | Inflammation - genetics | Adenylyl Cyclases - genetics | Muscle, Smooth, Vascular - enzymology | Life Sciences | Cellular Biology | Cardiovascular Disease | Molecular Bases of Disease | Vascular Smooth Muscle Cells | AC8 | Notch Signaling Pathway | Atherosclerosis | Adenylate Cyclase | VSMC Trans-differentiation | Pathological Vascular Remodeling | Camp
Journal Article
Atherosclerosis, ISSN 0021-9150, 2014, Volume 237, Issue 2, pp. e11 - e12
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 1/2013, Volume 373, Issue 1, pp. 95 - 105
Journal Article
Planta Medica, ISSN 0032-0943, 11/2015, Volume 81, Issue 16, p. SL3B_02
Excessive proliferation of vascular smooth muscle cells (VSMC) plays a major role in cardiovascular disease and greatly contributes to restenosis, the... 
Care and treatment | Research | Cardiovascular diseases | Natural products
Conference Proceeding
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0202354
Journal Article
Medical Science Monitor, ISSN 1234-1010, 07/2018, Volume 24, pp. 4894 - 4904
Background: There is accumulating evidence demonstrating that microRNAs (miRNA) play essential roles in proliferation, migration, and invasion of vascular... 
Muscle, smooth, vascular | Transforming growth factor beta | MicroRNAs | MEDICINE, RESEARCH & EXPERIMENTAL | SMAD4 | METASTASIS | TRANSCRIPTION | EPITHELIAL-MESENCHYMAL TRANSITION | Muscle, Smooth, Vascular | COLORECTAL-CANCER | PROSTATE-CANCER CELLS | DIFFERENTIATION | PROMOTES | EXPRESSION | Transforming Growth Factor beta
Journal Article
Journal Article
Medical Science Monitor, ISSN 1234-1010, 07/2018, Volume 24, pp. 4851 - 4860
Background: It has been proven that phenotype shifting, from the contractile phenotype to the synthetic phenotype, of vascular smooth muscle cells (VSMCs),... 
Cell proliferation | Angiotensin II | Emigration and immigration | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | Cell Proliferation | PHOSPHORYLATION | ATHEROSCLEROSIS | MECHANISMS | ANTIAGING PROTEIN KLOTHO | INFLAMMATION | CARDIOVASCULAR-DISEASE | DIFFERENTIATION | EXPRESSION | PROGRESSION | Emigration and Immigration
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2011, Volume 107, Issue 8, pp. 53A - 53A
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 29, pp. 26238 - 26249
Cyclic nucleotide phosphodiesterase 3 (PDE3) is an important regulator of cyclic adenosine monophosphate (cAMP) signaling within the cardiovascular system. In... 
MIGRATION | INSULIN REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MESANGIAL CELLS | NITRIC-OXIDE | ATHEROSCLEROSIS | GROWTH-FACTOR | NUCLEOTIDE PHOSPHODIESTERASES | DIFFERENTIAL REGULATION | EXPRESSION | CAMP | Cell Cycle - genetics | Gene Expression Regulation, Enzymologic - drug effects | RNA, Small Interfering - genetics | Cyclic Nucleotide Phosphodiesterases, Type 3 - genetics | Muscle, Smooth, Vascular - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 3 - deficiency | Phosphorylation - genetics | MAP Kinase Signaling System - genetics | Biocatalysis - drug effects | Gene Deletion | Cell Cycle Proteins - genetics | DNA - biosynthesis | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Platelet-Derived Growth Factor - pharmacology | Gene Knockout Techniques | Muscle, Smooth, Vascular - cytology | Proto-Oncogene Proteins c-raf - metabolism | Animals | MAP Kinase Signaling System - drug effects | Gene Expression Regulation, Enzymologic - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Dual Specificity Phosphatase 1 - metabolism | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Muscle, Smooth, Vascular - enzymology | Mitogen-Activated Protein Kinases - metabolism | MAP Kinases (MAPKs) | Protein Kinase A (PKA) | CREB | Cell Cycle | Signal Transduction | Retinoblastoma (Rb) | Cell Growth | ERK Signaling | VSMC | Cyclic AMP (cAMP) | Cell Biology
Journal Article
Atherosclerosis, ISSN 0021-9150, 2015, Volume 241, Issue 1, pp. e77 - e78
Journal Article
Vascular Pharmacology, ISSN 1537-1891, 2016, Volume 81, pp. 75 - 82
Journal Article
Canadian Journal of Cardiology, ISSN 0828-282X, 2012, Volume 28, Issue 5, pp. S148 - S149
Journal Article