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2014, 2014, Handbook of experimental pharmacology, ISBN 3642415873, Volume 221, viii, 295
This volume of Springer's Handbook of Experimental Pharmacology explores the wide range of factors relating to sodium channels, from their biophysical... 
Sodium channels | Voltage-Gated Sodium Channels | Ion channels | Research | Methodology | Neurosciences | Biomedicine | Protein Structure | Pharmacology/Toxicology | Cardiology | Membrane Biology | Calcium channels | Biophysics
Book
Science, ISSN 0036-8075, 03/2019, Volume 363, Issue 6433, pp. 1278 - 1279
Voltage-gated sodium channels (VGSCs) are primarily responsible for initiation of action potentials in many excitable cells such as nerves and muscles. Mammals... 
MULTIDISCIPLINARY SCIENCES | Sodium | Scorpion Venoms | Sodium Channels | Electric potential | Phenotypes | Channel opening | Deactivation | Channel gating | Muscles | Homology | Pharmacology | Selectivity | Inactivation | Channels | Domains | Proteins | Allosteric properties | Pain | Spiders | Isoforms | Nerves | Sodium channels (voltage-gated) | Toxins | Mutation | Gating | Index Medicus
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 5/2010, Volume 328, Issue 5980, pp. 906 - 909
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8428 - 8433
Voltage-gated sodium channels are important targets for the development of pharmaceutical drugs, because mutations in different human sodium channel isoforms... 
Sodium channels | Bromine | Maps | Sodium | Channel blockers | Crystals | Atoms | Binding sites | Crystal structure | Local anesthetics | Pharmacology | QUALITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | NA+ CHANNELS | MOLECULAR DETERMINANTS | INHIBITION | LOCAL-ANESTHETICS | LIDOCAINE | pharmacology | DRUGS | crystal structure | STATE-DEPENDENT BLOCK | BINDING | Humans | NAV1.1 Voltage-Gated Sodium Channel - genetics | Bacterial Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - chemistry | Ion Channel Gating - physiology | HEK293 Cells | Sodium Channels - metabolism | Membrane Potentials - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Triazines - metabolism | Triazines - pharmacology | Alphaproteobacteria - metabolism | Bacterial Proteins - genetics | Models, Molecular | Sodium Channel Blockers - metabolism | Sodium Channel Blockers - pharmacology | Binding Sites - genetics | Membrane Potentials - physiology | Alphaproteobacteria - chemistry | Sequence Homology, Amino Acid | Alphaproteobacteria - genetics | Ion Channel Gating - genetics | Sodium Channels - chemistry | Bacterial Proteins - metabolism | Sodium Channels - genetics | Mutation | Ion Channel Gating - drug effects | Physiological aspects | Prokaryotes | Cardiovascular disease | Eukaryotes | Index Medicus | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 9, pp. 3558 - 3563
Voltage-gated sodium channels underlie the rapid regenerative upstroke of action potentials and are modulated by cytoplasmic calcium ions through a poorly... 
Proteins | Sodium channels | Calcium | Brugada syndrome | Sodium | Electrophysiology | Titration | Physiological regulation | Crystal structure | Intelligence quotient | Cardiac arrhythmia | Crystallography | Patch-clamp electrophysiology | Structural biology | cardiac arrhythmia | CONFORMATIONAL ADAPTATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | INACTIVATION GATE | LONG-QT SYNDROME | EF-HAND DOMAIN | SOLUTION NMR STRUCTURE | patch-clamp electrophysiology | crystallography | BRUGADA-SYNDROME | APO-CALMODULIN | CARDIAC EXCITABILITY | structural biology | CALMODULIN-BINDING | Brugada Syndrome - genetics | Humans | Molecular Sequence Data | Crystallography, X-Ray | Sodium Channels - physiology | Sodium - metabolism | Calcium - chemistry | Ion Channel Gating - physiology | Calcium - physiology | Calmodulin - chemistry | NAV1.5 Voltage-Gated Sodium Channel | Protein Structure, Tertiary | Amino Acid Sequence | Models, Molecular | Recombinant Fusion Proteins - chemistry | Amino Acid Motifs | Macromolecular Substances | Protein Interaction Mapping | Sequence Homology, Amino Acid | Calmodulin - physiology | Patch-Clamp Techniques | Sequence Alignment | Membrane Potentials | Sodium Channels - chemistry | Long QT Syndrome - genetics | Protein Conformation | Ions | Physiology | Mutation | Heart | Calcium channels (voltage-gated) | Action potential | Data processing | Calcium-binding protein | Calorimetry | Sodium channels (voltage-gated) | Calmodulin | Index Medicus | Biological Sciences
Journal Article
Journal Article
06/2018, Handbook of Experimental Pharmacology, ISBN 3319902830, Volume 246, 448
This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their pharmacology and related diseases. Among the topics discussed are... 
Medicine | Human genetics | Human Genetics | Biomedicine | Protein Structure | Human Physiology | Pharmacology/Toxicology
eBook
Science, ISSN 0036-8075, 10/2018, Volume 362, Issue 6412, p. 306
Journal Article