X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (622) 622
vpr gene products, human immunodeficiency virus (336) 336
virology (313) 313
viruses (289) 289
index medicus (262) 262
gene products, vpr - metabolism (252) 252
hiv-1 - genetics (246) 246
virus diseases (242) 242
hiv-1 - physiology (229) 229
hiv (201) 201
cell line (196) 196
hiv-1 - metabolism (188) 188
animals (186) 186
gene products, vpr - genetics (186) 186
immunodeficiency-virus type-1 (186) 186
biochemical phenomena, metabolism, and nutrition (176) 176
hela cells (174) 174
vpr gene products, human immunodeficiency virus - metabolism (171) 171
vpr (168) 168
biochemistry & molecular biology (157) 157
hiv-1 (156) 156
molecular sequence data (155) 155
apoptosis (149) 149
cell-cycle arrest (138) 138
amino acid sequence (134) 134
human-immunodeficiency-virus (124) 124
virus replication (119) 119
proteins (118) 118
cell cycle (114) 114
infection (113) 113
cell biology (110) 110
vpr gene products, human immunodeficiency virus - genetics (106) 106
replication (103) 103
vpr protein (95) 95
research article (94) 94
protein binding (92) 92
hiv infections - virology (90) 90
gene products, vpr - physiology (89) 89
cells, cultured (87) 87
transfection (87) 87
mutation (86) 86
immunology (84) 84
mutational analysis (84) 84
research (84) 84
infectious diseases (83) 83
in-vivo (81) 81
nuclear-localization (81) 81
t-cells (81) 81
cell nucleus - metabolism (78) 78
hiv-1 - pathogenicity (78) 78
hiv-1 vpr (77) 77
gene (72) 72
gene expression (71) 71
protein (70) 70
human immunodeficiency virus (67) 67
health aspects (66) 66
microbiology (66) 66
viral proteins (63) 63
expression (62) 62
base sequence (60) 60
gene products, vpr - chemistry (60) 60
g2 phase (58) 58
mice (57) 57
virion incorporation (57) 57
macrophages - virology (55) 55
multidisciplinary sciences (55) 55
cell-cycle (54) 54
article (53) 53
human immunodeficiency virus--hiv (53) 53
type-1 vpr (51) 51
biology (50) 50
dna-binding proteins - metabolism (50) 50
hiv infections - metabolism (50) 50
cells (49) 49
gene expression regulation, viral (49) 49
infections (49) 49
recombinant fusion proteins - metabolism (49) 49
viral regulatory and accessory proteins - metabolism (48) 48
activation (47) 47
macrophages (47) 47
analysis (46) 46
host-pathogen interactions (46) 46
jurkat cells (45) 45
hek293 cells (44) 44
physiological aspects (43) 43
in-vitro (42) 42
aids (41) 41
binding sites (41) 41
dna (41) 41
gene-expression (41) 41
medicine (41) 41
signal transduction (41) 41
hiv infection (40) 40
nuclear import (40) 40
virus-cell interactions (40) 40
blotting, western (39) 39
cd4-positive t-lymphocytes - virology (39) 39
phosphorylation (39) 39
t-lymphocytes - virology (39) 39
viral-protein-r (39) 39
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Virology, ISSN 0042-6822, 10/2018, Volume 523, pp. 121 - 128
The HIV-1 accessory protein Vpr displays various activities that can favor viral replication such as G cell cycle arrest. Vpr also modulates host gene... 
HIV-1 | CD62L | Vpr | DDR | Nef | ATR | TRANSCRIPTION FACTORS | PROTEIN VPR | ACTIVATION | DNA-DAMAGE RESPONSE | NKG2D RECEPTOR | HUMAN-IMMUNODEFICIENCY-VIRUS | CLASS-I HDACS | VIROLOGY | LIGANDS | TYPE-1 | T-CELLS | Ataxia Telangiectasia Mutated Proteins - metabolism | Humans | L-Selectin - genetics | vif Gene Products, Human Immunodeficiency Virus - genetics | RNA, Messenger - metabolism | L-Selectin - metabolism | vif Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - metabolism | CD4-Positive T-Lymphocytes - virology | vpr Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - metabolism | Signal Transduction | Jurkat Cells | RNA, Messenger - genetics | Viral Regulatory and Accessory Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | HIV-1 - genetics | Viral Regulatory and Accessory Proteins - metabolism | Host-Pathogen Interactions | Human Immunodeficiency Virus Proteins - metabolism | G2 Phase Cell Cycle Checkpoints - genetics | Histones - genetics | nef Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - genetics | Histones - metabolism | Primary Cell Culture | Ataxia Telangiectasia Mutated Proteins - genetics | vpr Gene Products, Human Immunodeficiency Virus - genetics | RNA | T cells | HIV (Viruses) | Gene expression | Analysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9975 - 9980
During the early stages of HIV-1 replication the conical capsid composed of p24 CA protein dissociates from the rest of the cytoplasmic viral complex by a... 
Half lives | HIV | Memory interference | Virions | Reverse transcription | Viruses | Infections | Kinetics | Capsid | HIV 1 | Early events | Retrovirus | CAPSID PROTEIN | CELLS | retrovirus | PREINTEGRATION COMPLEX | MULTIDISCIPLINARY SCIENCES | HOST RESTRICTION | HUMAN-IMMUNODEFICIENCY-VIRUS | INHIBITION | early events | RESISTANCE | INFECTION | ASSOCIATION | TYPE-1 CORE | Anti-HIV Agents - pharmacology | Cyclosporine - pharmacology | Virus Replication - genetics | Humans | Virion - genetics | Green Fluorescent Proteins - genetics | Recombinant Fusion Proteins - metabolism | Reverse Transcription | HIV Core Protein p24 - genetics | Time Factors | HEK293 Cells | Macrolides - pharmacology | vpr Gene Products, Human Immunodeficiency Virus - metabolism | Cell Line | Green Fluorescent Proteins - metabolism | HIV-1 - metabolism | Virus Replication - drug effects | HIV-1 - genetics | Virion - metabolism | Human Immunodeficiency Virus Proteins - metabolism | Nevirapine - pharmacology | Animals | HIV Core Protein p24 - metabolism | Recombinant Fusion Proteins - genetics | Human Immunodeficiency Virus Proteins - genetics | Luminescent Proteins - genetics | HeLa Cells | Microscopy, Fluorescence | vpr Gene Products, Human Immunodeficiency Virus - genetics | Luminescent Proteins - metabolism | Genetic aspects | Research | Genetic transcription | HIV (Viruses) | Health aspects | Biological Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2014, Volume 289, Issue 51, pp. 35102 - 35110
Journal Article
PLoS pathogens, ISSN 1553-7366, 07/2007, Volume 3, Issue 7, pp. e94 - 0927
Despite the formidable mutational capacity and sequence diversity of HIV-1, evidence suggests that viral evolution in response to specific selective pressures... 
T-LYMPHOCYTE ESCAPE | CELL RESPONSES | VARIANTS | IMMUNE PRESSURE | PEPTIDE MOTIFS | MICROBIOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | SELECTION | TYPE-1 INFECTION | PARASITOLOGY | DISEASE PROGRESSION | PRIMARY INFECTION | Minor Histocompatibility Antigens | Humans | Molecular Sequence Data | Epitopes, T-Lymphocyte - genetics | Phylogeny | CD4-Positive T-Lymphocytes - immunology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Epitopes, T-Lymphocyte - immunology | vpr Gene Products, Human Immunodeficiency Virus - metabolism | Amino Acid Sequence | Viral Regulatory and Accessory Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Genes, MHC Class I - physiology | Selection, Genetic | CD4 Lymphocyte Count | Histocompatibility Antigens Class I - genetics | HIV-1 - genetics | Viral Regulatory and Accessory Proteins - metabolism | Polymorphism, Genetic | Human Immunodeficiency Virus Proteins - metabolism | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | Gene Expression Regulation, Viral | Human Immunodeficiency Virus Proteins - genetics | Mutation | vpr Gene Products, Human Immunodeficiency Virus - genetics | Evolution, Molecular | Evolution | Genetic aspects | Research | HIV (Viruses) | Viral genetics | Viruses | Immunology | Virology | Studies | Medical research | Genes
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e106418
Macrophages act as reservoirs of human immunodeficiency virus type 1 (HIV-1) and play an important role in its transmission to other cells. HIV-1 Vpr is a... 
NUCLEAR IMPORT | UBIQUITIN LIGASE | I INTERFERONS | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | CELL-CYCLE ARREST | TERMINALLY TRUNCATED FORM | T-CELLS | VIRAL-PROTEIN-R | PRE-MESSENGER-RNA | HIV-1-INFECTED MACROPHAGES | Dependovirus - genetics | Phosphorylation | Interferons - pharmacology | Oligonucleotide Array Sequence Analysis - methods | Humans | Cells, Cultured | Gene Expression Profiling - methods | Interferon Regulatory Factor-7 - genetics | Immunity, Innate | STAT1 Transcription Factor - genetics | Interferon Regulatory Factor-7 - metabolism | Gene Expression Regulation - drug effects | Dependovirus - physiology | Macrophages - metabolism | STAT1 Transcription Factor - metabolism | Macrophages - virology | HEK293 Cells | Macrophages - drug effects | HeLa Cells | vpr Gene Products, Human Immunodeficiency Virus - metabolism | vpr Gene Products, Human Immunodeficiency Virus - genetics | Infection | Adenoviruses | Genes | Cellular signal transduction | Interferon | HIV (Viruses) | Macrophages | Biological response modifiers | Health aspects | Flow cytometry | Transcription | Pathogenesis | Viruses | Infections | Proteins | Vpr protein | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Cell cycle | Post-translation | Stat1 protein | Deoxyribonucleic acid--DNA | Recombinant | Immune system | Tyrosine | Antigens | Cytomegalovirus | Immune response | Myxovirus resistance proteins | Dendritic cells | Gene expression | Disease prevention | Interferon regulatory factor 7 | Monocytes | Infectious diseases | Disease transmission | DNA microarrays | Transduction | TRAIL protein | Apoptosis | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | DNA | Human immunodeficiency virus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68108
The precursor group-specific antigen (wpr55(Gag)) is central to HIV-1 assembly. Its expression alone is sufficient to assemble into virus-like particles. It... 
5-UNTRANSLATED REGION | HOST PROTEIN-SYNTHESIS | EFFICIENT CLEAVAGE | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | POLY(A)-BINDING PROTEIN | MEDIATED TRANSLATION | EUKARYOTIC TRANSLATION | RIBOSOME ENTRY SITE | GENOMIC RNA | CAP-INDEPENDENT TRANSLATION | Cell Line | Genome, Viral | HIV-1 - metabolism | gag Gene Products, Human Immunodeficiency Virus - biosynthesis | tat Gene Products, Human Immunodeficiency Virus - genetics | Humans | RNA, Messenger - genetics | Regulatory Sequences, Ribonucleic Acid | Peptide Chain Initiation, Translational | HIV-1 - genetics | RNA, Messenger - metabolism | Genetic Vectors - genetics | RNA, Viral - genetics | Gene Expression Regulation, Viral | RNA, Viral - metabolism | vpr Gene Products, Human Immunodeficiency Virus - metabolism | Gene Order | vpr Gene Products, Human Immunodeficiency Virus - genetics | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Messenger RNA | HIV (Viruses) | Proteases | Genetic translation | Health aspects | Transcription | Laboratories | Foot & mouth disease | Replication initiation | Viruses | Infections | Biology | mRNA | Virus-like particles | Vpr protein | Synthesis | Gag protein | Human immunodeficiency virus--HIV | Assembly | Internal ribosome entry site | Translation | Translation initiation | Gene expression | Virology | Medicine | Studies | Tat protein | Encapsidation | Ribonucleic acids | Protein synthesis | Initiation factor eIF-4G | Binding sites | Viral infections | HIV | Human immunodeficiency virus
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 10/2016, Volume 23, Issue 10, pp. 933 - 939
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 51, pp. 21117 - 21127
The viral protein R (Vpr) is an accessory virulence factor of HIV-1 that facilitates infection in immune cells. Cellular functions of Vpr are tied to its... 
G ARREST | ACTIVATION | COMPLEX | CELL NUCLEAR ANTIGEN | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACCESSORY PROTEINS | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | REPLICATION FORK | CYCLE | Transcription Factors - chemistry | Humans | Protein Multimerization | Ubiquitin-Protein Ligases - antagonists & inhibitors | Recombinant Fusion Proteins - metabolism | DNA-Binding Proteins - metabolism | Ubiquitination | RNA Interference | Gene Deletion | HEK293 Cells | Carrier Proteins - chemistry | Protein Interaction Domains and Motifs | vpr Gene Products, Human Immunodeficiency Virus - metabolism | Binding Sites | Dimerization | Oligopeptides - chemistry | Peptide Fragments - genetics | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | vpr Gene Products, Human Immunodeficiency Virus - chemistry | Oligopeptides - genetics | Carrier Proteins - antagonists & inhibitors | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Oligopeptides - metabolism | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Transcription Factors - metabolism | Carrier Proteins - genetics | Point Mutation | Peptide Fragments - chemistry | Carrier Proteins - metabolism | WD40 Repeats | Cell Line, Tumor | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | vpr Gene Products, Human Immunodeficiency Virus - genetics | ubiquitin ligase | Molecular Bases of Disease | human immunodeficiency virus (HIV) | polyubiquitin chain | Vpr | virulence factor | protein degradation | ubiquitin
Journal Article