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Molecular Nutrition & Food Research, ISSN 1613-4125, 09/2018, Volume 62, Issue 18, pp. e1700916 - n/a
The potential of isothiocyanates to antagonize the carcinogenicity of structurally diverse chemicals has been established in animals. A feasible mechanism of... 
cancer chemoprevention | isothiocyanates | cytochromes P450 | detoxification | glucosinolates | RAT-LIVER | FOOD SCIENCE & TECHNOLOGY | DIETARY PHENETHYL ISOTHIOCYANATE | DRUG-METABOLIZING-ENZYMES | BENZYL ISOTHIOCYANATE | II ENZYME-SYSTEMS | DNA ADDUCT FORMATION | CHEMOPREVENTIVE AGENT | GLUTATHIONE-S-TRANSFERASE | BROCCOLI SPROUT BEVERAGES | DNA Damage - drug effects | Inactivation, Metabolic | Humans | Glutathione Transferase - metabolism | Glucosinolates - metabolism | Xenobiotics - toxicity | Carcinogens - metabolism | Carcinogens - toxicity | Isothiocyanates - metabolism | Animals | Glucuronosyltransferase - metabolism | Cell Line, Tumor | Thiocyanates - pharmacology | Xenobiotics - metabolism | Epoxide Hydrolases - metabolism | Hepatocytes - drug effects | Isothiocyanates - pharmacology | Disease Models, Animal | Sulfides - pharmacology | Cytochrome P-450 | Cytochrome | Phenethyl isothiocyanate | Genotoxicity | Glucosinolates | Epoxide hydrolase | Carcinogens | Metabolites | Inactivators | Biocompatibility | Deoxyribonucleic acid--DNA | Inducers | Glutathione | Cytochromes P450 | Sulforafan | Enzymes | Excretion | Cytochrome P450 | Quinone | Detoxification | Isothiocyanate | Aliphatic compounds | Chemicals | Organic chemistry | Tobacco | Chemotherapy | Hepatocytes | In vivo methods and tests | Carcinogenicity | Smoking | Cancer | Reductase | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 09/2011, Volume 25, Issue 17, pp. 1796 - 1806
Living organisms, from bacteria to humans, display a coordinated transcriptional response to xenobiotic exposure, inducing enzymes and transporters that... 
Insecticide resistance | Transcriptional control | Xenobiotics | Nrf2 | Gene regulation | OXIDATIVE STRESS | ARYL-HYDROCARBON | xenobiotics | RECEPTOR | DEVELOPMENTAL BIOLOGY | insecticide resistance | INDUCTION | MELANOGASTER CYTOCHROME-P450 GENES | CELL BIOLOGY | transcriptional control | gene regulation | GENETICS & HEREDITY | GENOME-WIDE ANALYSIS | OVER-EXPRESSION | JUVENILE-HORMONE | BARBITAL-INDUCED EXPRESSION | Inactivation, Metabolic | Cytochrome P-450 Enzyme System - metabolism | Malathion - pharmacology | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Xenobiotics - pharmacology | Drosophila melanogaster - metabolism | Cytochrome P450 Family 6 | Xenobiotics - metabolism | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Insecticides - pharmacology | Malathion - pharmacokinetics | Promoter Regions, Genetic | Drosophila melanogaster - drug effects | Gene Expression Regulation - drug effects | Drug Resistance - genetics | Animals | Insecticides - metabolism | NF-E2-Related Factor 2 - metabolism | Cytochrome P-450 Enzyme System - genetics | Protein Binding | Drosophila Proteins - genetics | Insecticides - pharmacokinetics | Metabolic conjugation | Analysis | Drosophila | Physiological aspects | Genetic aspects | Genetic transcription | Research | Chemical properties | Research Paper
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Journal Article
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 07/2018, Volume 209, pp. 9 - 17
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2019, Volume 29, Issue 5, pp. 1182 - 1191.e4
In , mitochondrial dysfunction caused by mutation or toxins activates programs of detoxification and immune response. A genetic screen for mutations that... 
xenobiotic surveillance | detoxification and immune responses | lifespan | mitochondrion | INACTIVATION | PATHWAYS | CYTOCHROME-P450 | LONGEVITY | PATHOGEN | METABOLISM | ENDOCRINOLOGY & METABOLISM | RESISTANCE | GENOME | RNAI SCREEN | SUBUNIT | CELL BIOLOGY | Hormones | Molecular biology | Genes | Genetic screening
Journal Article
The Plant cell, ISSN 1040-4651, 10/2018, Volume 30, Issue 10, pp. 2495 - 2511
When exposed to unfavorable environmental conditions, plants can absorb light energy in excess of their photosynthetic capacities, with the surplus energy... 
ARABIDOPSIS-THALIANA | LIPID-PEROXIDATION | CAROTENOID OXIDATION-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TGA TRANSCRIPTION FACTORS | PLANT SCIENCES | CELL BIOLOGY | HIGH-LIGHT | SALICYLIC-ACID | GENE-EXPRESSION | PHOTOSYSTEM-II | SINGLET OXYGEN | HERBICIDE SAFENERS | Life Sciences
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Journal Article